miR-126 Cancer Research Results

miR-126, miR-126: Click to Expand ⟱

Source:

Type: tumour-suppressor miRNA

miR-126 is involved in the regulation of angiogenesis, which is the process of forming new blood vessels.
miR-126 is downregulated in many types of cancer, including breast, lung, colon, and pancreatic cancer.
The downregulation of miR-126 has been associated with poor prognosis and increased metastasis in cancer patients.

BC, Breast Cancer: Click to Expand ⟱

Breast Cancer

Scientific Papers found: Click to Expand⟱

736-

Bor,

Evaluation of Boric Acid Treatment on microRNA-127-5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells

in-vitro,

BC,

MCF-7

45.69 mM

miR-126↑, COL1A1↓, Vim↓, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑, miR-127-5p↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

miR-127-5p↑, 1,

Migration ⓘ

CDH1↑, 1, COL1A1↓, 1, ITGA5↑, 1, ITGB1↑, 1, LAMA5↑, 1, Snail↑, 1, Vim↓, 1, Zeb1↑, 1,

Angiogenesis & Vasculature ⓘ

miR-126↑, 1,
Total Targets: 10

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: miR-126, miR-126

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells