eff Cancer Research Results

eff, efficacy: Click to Expand ⟱
Source:
Type:
Power to enhance an anti cancer effect
BC, Breast Cancer: Click to Expand ⟱
Breast Cancer
Scientific Papers found: Click to Expand⟱
5282- 3BP,  Rad,    3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
Glycolysis↓, RadioS↑, eff↑, GAPDH↓, PPP↑, GSH↓, ECAR↓,
5261- 3BP,    The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH
- in-vitro, BC, NA
eff↑, eff↓,
4400- AgNPs,  Rad,    Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells
- in-vitro, BC, MCF-7 - in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, MDA-MB-231
ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,
4415- AgNPs,  SDT,  CUR,    Examining the Impact of Sonodynamic Therapy With Ultrasound Wave in the Presence of Curcumin-Coated Silver Nanoparticles on the Apoptosis of MCF7 Breast Cancer Cells
- in-vitro, BC, MCF-7
tumCV↓, BAX↑, Casp3↑, Bcl-2↓, eff↑, ROS↑, sonoS↑, eff↑, MMP↓, Cyt‑c↑,
4413- AgNPs,  Anzaroot,    Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells
- in-vitro, BC, MCF-7
chemoP↑, TumCG↓, eff↑, CellMemb↑, selectivity↑, ROS↑, P53↑,
4374- AgNPs,    Enhancing antitumor activity of silver nanoparticles by modification with cell-penetrating peptides
- in-vitro, BC, MCF-7
eff↑, TumCD↑,
356- AgNPs,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF-7 - in-vitro, Bladder, HTB-22
Apoptosis↑, P53↑, iNOS↑, NF-kB↑, Bcl-2↓, ROS↑, SOD↑, TumCCA↑, eff↑, Catalase↑, other↑,
1440- AMQ,    Lysosomotropism depends on glucose: a chloroquine resistance mechanism
- in-vitro, BC, 4T1
eff↑, Apoptosis↓, Necroptosis↑, eff↓, ChemoSen↑, eff↓,
1348- And,    Andrographolide Inhibits ER-Positive Breast Cancer Growth and Enhances Fulvestrant Efficacy via ROS-FOXM1-ER-α Axis
- in-vitro, BC, MCF-7 - in-vitro, BC, T47D - in-vivo, NA, NA
ERα/ESR1↓, TumCG↓, ROS↑, FOXM1↓, eff↑,
5376- ART/DHA,    Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29 - in-vitro, CRC, SW48 - in-vitro, BC, MDA-MB-453
Ferroptosis↑, Ferritin↓, Iron↑, eff↑, TumAuto↑, LC3II↑, ROS↑,
3175- Ash,  SFN,    Withaferin A and sulforaphane regulate breast cancer cell cycle progression through epigenetic mechanisms
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7
DNMTs↓, HDAC↓, eff↑,
1355- Ash,    Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7 - in-vitro, Nor, HMEC
eff↑, mt-ROS↑, mitResp↓, OXPHOS↓, compIII↑, BAX↑, Bak↑, other↓, ATP∅, *ROS∅,
1360- Ash,  immuno,    Withaferin A Increases the Effectiveness of Immune Checkpoint Blocker for the Treatment of Non-Small Cell Lung Cancer
- in-vitro, Lung, H1650 - in-vitro, Lung, A549 - in-vitro, CRC, HCT116 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
PD-L1↑, eff↓, ROS↑, ER Stress↑, Apoptosis↑, BAX↑, Bak↑, BAD↑, Bcl-2↓, XIAP↓, survivin↓, cl‑PARP↑, CHOP↑, p‑eIF2α↑, ICD↑, eff↑,
1433- Ash,  SFN,    A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
eff↑, Bcl-2↓, BAX↑, tumCV↓, DNMT1↓, DNMT3A↓, HDAC↓,
5173- Ash,  2DG,    Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468 - in-vitro, BC, T47D
autoF↓, lysosome↓, TumAuto↑, p‑LDH↓, ATP↓, AMPK↑, eff↑, TumCG↓, CTSD↓, CTSB↓, CTSL↑, cl‑PARP1↑, LDHA↓, TCA↓,
4818- ASTX,  MEL,    Effect of astaxanthin and melatonin on cell viability and DNA damage in human breast cancer cell lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, T47D - in-vitro, Nor, MCF10
TumCD↑, DNAdam↑, *antiOx↑, *AntiTum↑, Inflam↓, tumCV↓, Bcl-2↓, Apoptosis↓, selectivity↑, eff↑, Dose↓,
4985- ATV,  Dipy,    Repurposing of the Cardiovascular Drug Statin for the Treatment of Cancers: Efficacy of Statin-Dipyridamole Combination Treatment in Melanoma Cell Lines
- in-vivo, Melanoma, SK-MEL-28 - in-vitro, BC, MDA-MB-435
HMG-CoA↓, SREBP2↓, eff↑, HMGCR⇅, ChemoSen↑,
5543- BBM,    Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo
- in-vivo, Lung, B16-F10 - vitro+vivo, Lung, A549 - in-vitro, BC, MDA-MB-231
BioAv↓, Half-Life↓, eff↑, TumMeta↓, TumCP↓, TumCG↓, Apoptosis↑, TumCCA↑, MMP2↓, MMP9↓, VEGF↓, Bcl-2↓, eff↑, EPR↑,
1473- BCA,  SFN,    An Insight on Synergistic Anti-cancer Efficacy of Biochanin A and Sulforaphane Combination Against Breast Cancer
- in-vitro, BC, MCF-7
eff↑, ROS↑, other↑, ERK↓, Apoptosis↑,
5510- bemA,    Combined inhibition of ACLY and CDK4/6 reduces cancer cell growth and invasion
- in-vitro, BC, MDA-MB-231 - in-vitro, PC, NA
eff↑, Apoptosis↑, TumCI↓, ACLY↓, LDL↓, eff↑, TumCP↓,
5591- BetA,    Advances and challenges in betulinic acid therapeutics and delivery systems for breast cancer prevention and treatment
- Review, BC, NA
BioAv↓, BioAv↑, selectivity↑, eff↑, angioG↓, *antiOx↑, *Inflam↓, MMP↓, Bcl-2↓, BAX↑, Casp9↑, Casp3↑, GRP78/BiP?, ER Stress↑, PERK↑, CHOP↑, ChemoSen↑, SESN2↑, ROS↑, MOMP↓, MAPK↑, Cyt‑c↑, AIF↑, STAT3↓, FAK↓, TIMP2↑, TumCMig↓, TumCI↓, Sp1/3/4↓, TumCCA↑, DNAdam↑,
2755- BetA,    Cytotoxic Potential of Betulinic Acid Fatty Esters and Their Liposomal Formulations: Targeting Breast, Colon, and Lung Cancer Cell Lines
- in-vitro, Colon, HT29 - in-vitro, BC, MCF-7 - in-vitro, Lung, H460
eff↑, Casp3↑, Casp7↑, NF-kB↓,
2050- Buty,    The Role of Sodium Phenylbutyrate in Modifying the Methylome of Breast Cancer Cells
- in-vitro, BC, MCF-7
eff↑, HDAC↓, TumCG↓,
5867- CA,    Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines
- in-vitro, Pca, DU145 - in-vitro, Liver, Hep3B - in-vitro, AML, K562 - in-vitro, Pca, PC3 - in-vitro, BC, MDA-MB-231
TumCP↓, eff↑, other↝,
5874- CA,    Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells
- vitro+vivo, BC, T47D - in-vitro, BC, MCF10
AntiTum↓, ROS↑, cJun↑, p‑p38↑, Apoptosis↑, ROS↑, eff↑, TumCP↓, glucose↓, BAX↑, PARP↑, Bcl-2↓, eff↓, Ki-67↓, toxicity↝, STAT3↓, PI3K↓, Akt↓, mTOR↓,
5774- CA,  CAPE,    Caffeic Acid Versus Caffeic Acid Phenethyl Ester in the Treatment of Breast Cancer MCF-7 Cells: Migration Rate Inhibition
- NA, BC, MCF-7
TumCMig↓, Wound Healing↑, eff↑, tumCV↓,
5821- capec,  docx,    Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results
- Trial, BC, NA
eff↑, OS↑,
5903- CAR,  TV,    Combined Cytotoxic Effects of Carvacrol-Based Essential Oil Formulations
- in-vitro, BC, MDA-MB-231
BioAv↑, MPT↑, ROS↑, Casp↑, eff↑, PI3K↓, Akt↓, TumCCA↑, Apoptosis↑, Cyt‑c↑, cl‑PARP↑, MPT↑,
5899- CAR,  TV,    Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and Anticancer Activities against Breast Cancer Lines
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
eff↑, selectivity↑, BioAv↝, BBB↑, *toxicity↝, *antiOx↑, COX2↓, 5LO↓,
5916- Cats,  Chemo,    Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial
- Trial, BC, NA
*DNAdam↓, Neut↓, eff↑, Imm↑, Dose↝,
5966- CEL,    Determine whether administering celecoxib during radiotherapy can reduce the risk of recurrence of triple-negative breast cancer. Pilot study
- Trial, BC, NA
Risk↓, eff↑,
5949- Cela,    Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor
- in-vitro, BC, MCF-7
CXCR4↓, eff↑, TumCI↓, TumMeta↓,
6020- CGA,  BetaL,    Chlorogenic Acid Enhances Beta‐Lapachone‐Induced Cell Death by Suppressing Autophagy in NQO1‐Positive Cancer Cells
- in-vitro, BC, MDA-MB-231
eff↑, Apoptosis↑, PKA↑, eff↑,
5991- Chit,    Chitosan-Based Nanoencapsulated Essential Oils: Potential Leads against Breast Cancer Cells in Preclinical Studies
- Review, BC, NA
*other↝, *BioAv↓, eff↑, toxicity↓, eff↑, TumCD↑, Half-Life↑, selectivity↑, EPR↑, ROS↑, Apoptosis↑, eff↑,
5999- Chit,    How chitosan can help against breast cancer
- Review, BC, NA
eff↑, DDS↑, Half-Life↑, eff↑, eff↑,
6075- CHL,  docx,    The effect of the combination therapy with chlorophyllin, a glutathione transferase P1-1 inhibitor, and docetaxel on triple-negative breast cancer invasion and metastasis in vivo/in vitro
- vitro+vivo, BC, 4T1
TumCMig↓, eff↑, TumMeta↓, TumCCA↑, Trx↓, ROS↓, TumCD↑, GSTP1/GSTπ↓,
4770- CoQ10,  VitK2,    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
- in-vitro, BC, MDA-MB-231
other↑, *antiOx↑, Risk↓, other↑, TumMeta↓, ECM/TCF↓, Akt2↓, Ferroptosis↑, eff↑,
1603- Cu,  BP,  SDT,    Glutathione Depletion-Induced ROS/NO Generation for Cascade Breast Cancer Therapy and Enhanced Anti-Tumor Immune Response
- in-vitro, BC, 4T1 - in-vivo, NA, NA
GSH↓, Fenton↑, ROS↑, NO↑, sonoS↑, eff↑, NO↑, *toxicity∅, eff?,
1602- Cu,    A simultaneously GSH-depleted bimetallic Cu(ii) complex for enhanced chemodynamic cancer therapy†
- in-vitro, BC, MCF-7 - in-vitro, BC, 4T1 - in-vitro, Lung, A549 - in-vitro, Liver, HepG2
eff↑, GSH↓, H2O2↑, ROS↑, *BioAv↑, selectivity↑, TumCCA↑, Apoptosis↑, Fenton↑, *toxicity?,
1977- CUR,    Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors
- in-vitro, BC, MCF-7 - in-vitro, Cerv, HeLa - in-vitro, Lung, A549
TrxR↓, Dose↝, eff↑,
1864- DCA,  MET,    Dichloroacetate Enhances Apoptotic Cell Death via Oxidative Damage and Attenuates Lactate Production in Metformin-Treated Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, BC, T47D - in-vitro, Nor, MCF10
PDKs↓, eff↑, ROS↑, PDK1↓, lactateProd↓, p‑PDH↑, Dose∅, OCR↑, DNA-PK↑, γH2AX↑, cl‑PARP↑, selectivity↑, *toxicity∅,
1867- DCA,  Chemo,    Sensitization of breast cancer cells to paclitaxel by dichloroacetate through inhibiting autophagy
- in-vivo, BC, NA - in-vitro, BC, NA
TumCG↓, eff↑, OS↑, PDKs↓, PDH↑,
4455- DFE,    Ajwa Date (Phoenix dactylifera L.) Extract Inhibits Human Breast Adenocarcinoma (MCF7) Cells In Vitro by Inducing Apoptosis and Cell Cycle Arrest
- in-vitro, BC, MCF-7 - in-vitro, Nor, 3T3
TumCCA↑, P53↑, BAX↑, Casp3↑, MMP↓, Fas↑, FasL↑, Bcl-2↓, Apoptosis↑, TumCP↓, TUNEL↑, eff↑, selectivity↑,
2152- dietFMD,    Prolonged Nightly Fasting and Breast Cancer Prognosis
- Analysis, BC, NA
eff↑, Dose↓, Risk↓,
1848- dietFMD,  Chemo,    Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial
- Trial, BC, NA
ChemoSideEff↓, ChemoSen↑, eff↑,
1860- dietFMD,  Chemo,    Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape
- in-vitro, BC, SUM159 - in-vitro, BC, 4T1
PI3K↑, Akt↑, mTOR↑, CDK4↑, CDK6↑, hyperG↓, TumCG↓, TumVol↓, Casp3↑, BG↓, eff↑, eff∅, PKA↓, KLF5↓, p‑GSK‐3β↑, Nanog↓, OCT4↓, KLF2↓, eff↑, ROS↑, BIM↑, ASK1↑, PI3K↑, Akt↑, mTOR↑, CDK1↓, CDK4↑, CDK6↑, eff↑,
5386- docx,  AsP,    Co-delivery of docetaxel and palmitoyl ascorbate by liposome for enhanced synergistic antitumor efficacy
- vitro+vivo, Liver, HepG2 - in-vitro, BC, MCF-7 - in-vitro, Pca, PC3
Dose↝, ROS↑, eff↑, eff↑,
1608- EA,    Ellagic Acid from Hull Blackberries: Extraction, Purification, and Potential Anticancer Activity
- in-vitro, Cerv, HeLa - in-vitro, Liver, HepG2 - in-vitro, BC, MCF-7 - in-vitro, Lung, A549 - in-vitro, Nor, HUVECs
eff↑, Dose∅, *BioAv↑, selectivity↑, TumCP↓, Casp↑, PTEN↑, TSC1↑, mTOR⇅, Akt↓, PDK1↓, E6↓, E7↓, DNAdam↑, ROS↑, *BioAv↓, *BioEnh↑, *Half-Life∅,
1618- EA,    A comprehensive review on Ellagic acid in breast cancer treatment: From cellular effects to molecular mechanisms of action
- Review, BC, NA
TumCCA↑, TumCMig↓, TumCI↓, TumMeta↓, Apoptosis↑, TGF-β↓, SMAD3↓, CDK6↓, PI3K↓, Akt↓, angioG↓, VEGFR2↓, MAPK↓, NEDD9↓, NF-kB↓, eff↑, eff↑, RadioS↑, ChemoSen↑, DNAdam↑, eff↑, *toxicity∅, *toxicity∅,
1515- EGCG,  Phen,    Reciprocal Relationship Between Cytosolic NADH and ENOX2 Inhibition Triggers Sphingolipid-Induced Apoptosis in HeLa Cells
- in-vitro, Cerv, HeLa - in-vitro, Nor, MCF10 - in-vitro, BC, BT20
selectivity↑, ENOX2↓, NADH↑, SK↓, eff↑, aSmase↑,

Showing Research Papers: 1 to 50 of 95
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 95

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 1,   ENOX2↓, 1,   Fenton↑, 2,   Ferroptosis↑, 2,   GSH↓, 3,   GSTP1/GSTπ↓, 1,   H2O2↑, 1,   hyperG↓, 1,   ICD↑, 1,   Iron↑, 1,   NADH↑, 1,   OXPHOS↓, 1,   ROS↓, 1,   ROS↑, 19,   mt-ROS↑, 1,   SOD↑, 1,   Trx↓, 1,   TrxR↓, 1,  

Metal & Cofactor Biology ⓘ

Ferritin↓, 1,   KLF5↓, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↑, 1,   ATP↓, 1,   ATP∅, 1,   compIII↑, 1,   mitResp↓, 1,   MMP↓, 3,   MPT↑, 2,   OCR↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

ACLY↓, 1,   AMPK↑, 1,   ECAR↓, 1,   GAPDH↓, 1,   glucose↓, 1,   Glycolysis↓, 1,   HMG-CoA↓, 1,   lactateProd↓, 1,   p‑LDH↓, 1,   LDHA↓, 1,   LDL↓, 1,   PDH↑, 1,   p‑PDH↑, 1,   PDK1↓, 2,   PDKs↓, 2,   PPP↑, 1,   SREBP2↓, 1,   TCA↓, 1,  

Cell Death ⓘ

Akt↓, 4,   Akt↑, 2,   Apoptosis↓, 2,   Apoptosis↑, 12,   ASK1↑, 1,   aSmase↑, 1,   BAD↑, 1,   Bak↑, 2,   BAX↑, 7,   Bcl-2↓, 9,   BIM↑, 1,   Casp↑, 2,   Casp3↑, 5,   Casp7↑, 1,   Casp9↑, 1,   Cyt‑c↑, 3,   Fas↑, 1,   FasL↑, 1,   Ferroptosis↑, 2,   iNOS↑, 1,   MAPK↓, 1,   MAPK↑, 1,   MOMP↓, 1,   Necroptosis↑, 1,   p‑p38↑, 1,   SK↓, 1,   survivin↓, 1,   TumCD↑, 4,   TUNEL↑, 1,  

Kinase & Signal Transduction ⓘ

Sp1/3/4↓, 1,  

Transcription & Epigenetics ⓘ

cJun↑, 1,   other↓, 1,   other↑, 4,   other↝, 2,   sonoS↑, 2,   tumCV↓, 4,  

Protein Folding & ER Stress ⓘ

CHOP↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 2,   GRP78/BiP?, 1,   PERK↑, 1,  

Autophagy & Lysosomes ⓘ

autoF↓, 1,   LC3II↑, 1,   lysosome↓, 1,   SESN2↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair ⓘ

DNA-PK↑, 1,   DNAdam↑, 5,   DNMT1↓, 1,   DNMT3A↓, 1,   DNMTs↓, 1,   P53↑, 3,   PARP↑, 1,   cl‑PARP↑, 3,   cl‑PARP1↑, 1,   γH2AX↑, 2,  

Cell Cycle & Senescence ⓘ

CDK1↓, 1,   CDK4↑, 2,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State ⓘ

CTSB↓, 1,   CTSD↓, 1,   CTSL↑, 1,   ERK↓, 1,   FOXM1↓, 1,   p‑GSK‐3β↑, 1,   HDAC↓, 3,   HMGCR⇅, 1,   mTOR↓, 1,   mTOR↑, 2,   mTOR⇅, 1,   Nanog↓, 1,   OCT4↓, 1,   PI3K↓, 3,   PI3K↑, 2,   PTEN↑, 1,   STAT3↓, 2,   TumCG↓, 8,  

Migration ⓘ

5LO↓, 1,   Akt2↓, 1,   FAK↓, 1,   Ki-67↓, 1,   KLF2↓, 1,   MMP2↓, 1,   MMP9↓, 1,   NEDD9↓, 1,   PKA↓, 1,   PKA↑, 1,   SMAD3↓, 1,   TGF-β↓, 1,   TIMP2↑, 1,   TSC1↑, 1,   TumCI↓, 4,   TumCMig↓, 4,   TumCP↓, 6,   TumMeta↓, 5,  

Angiogenesis & Vasculature ⓘ

angioG↓, 2,   ECM/TCF↓, 1,   EPR↑, 2,   NO↑, 2,   VEGF↓, 1,   VEGFR2↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,   CellMemb↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   CXCR4↓, 1,   Imm↑, 1,   Inflam↓, 1,   Neut↓, 1,   NF-kB↓, 2,   NF-kB↑, 1,   PD-L1↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,   CDK6↑, 2,   ERα/ESR1↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 1,   ChemoSen↑, 5,   DDS↑, 1,   Dose↓, 3,   Dose↝, 4,   Dose∅, 2,   eff?, 1,   eff↓, 6,   eff↑, 64,   eff∅, 1,   Half-Life↓, 1,   Half-Life↑, 2,   RadioS↑, 3,   selectivity↑, 12,  

Clinical Biomarkers ⓘ

BG↓, 1,   E6↓, 1,   E7↓, 1,   ERα/ESR1↓, 1,   Ferritin↓, 1,   FOXM1↓, 1,   Ki-67↓, 1,   p‑LDH↓, 1,   PD-L1↑, 1,  

Functional Outcomes ⓘ

AntiTum↓, 1,   chemoP↑, 1,   ChemoSideEff↓, 1,   OS↑, 2,   Risk↓, 3,   toxicity↓, 1,   toxicity↝, 1,   TumVol↓, 1,   Wound Healing↑, 1,  
Total Targets: 195

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 4,   ROS∅, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioEnh↑, 1,   Half-Life∅, 1,  

Functional Outcomes ⓘ

AntiTum↑, 1,   toxicity?, 1,   toxicity↝, 1,   toxicity∅, 4,  
Total Targets: 13

Scientific Paper Hit Count for: eff, efficacy
6 Silver-NanoParticles
6 Magnetic Fields
5 Ashwagandha(Withaferin A)
5 Sulforaphane (mainly Broccoli)
5 Chemotherapy
4 immunotherapy
4 doxorubicin
4 Bicarbonate(Sodium)
4 salinomycin
3 Melatonin
3 Docetaxel
3 chitosan
3 Metformin
3 diet FMD Fasting Mimicking Diet
2 3-bromopyruvate
2 Radiotherapy/Radiation
2 SonoDynamic Therapy UltraSound
2 Curcumin
2 Betulinic acid
2 Carnosic acid
2 Carvacrol
2 Thymol-Thymus vulgaris
2 Copper and Cu NanoParticles
2 Dichloroacetate
2 Ascorbyl Palmitate
2 Ellagic acid
2 Gold NanoParticles
2 Magnetic Field Rotating
2 Vitamin C (Ascorbic Acid)
2 Resveratrol
2 Rosmarinic acid
2 Silymarin (Milk Thistle) silibinin
1 Anzaroot, Astragalus fasciculifolius Bioss
1 Amodiaquine
1 Andrographis
1 Artemisinin
1 2-DeoxyGlucose
1 Astaxanthin
1 Atorvastatin
1 Dipyridamole
1 Berbamine
1 Biochanin A
1 bempedoic acid
1 Butyrate
1 Caffeic acid
1 Caffeic Acid Phenethyl Ester (CAPE)
1 capecitabine
1 Cat’s Claw
1 Celecoxib
1 Celastrol
1 Chlorogenic acid
1 Beta‐Lapachone
1 Chlorophyllin
1 Coenzyme Q10
1 Vitamin K2
1 Black phosphorus
1 Date Fruit Extract
1 EGCG (Epigallocatechin Gallate)
1 PXD, phenoxodiol
1 Exercise
1 Gambogic Acid
1 Genistein (soy isoflavone)
1 Gemcitabine (Gemzar)
1 HydroxyCitric Acid
1 tamoxifen
1 Luteolin
1 Folic Acid, Vit B9
1 Propolis -bee glue
1 Phenethyl isothiocyanate
1 Paclitaxel
1 Piperlongumine
1 Quercetin
1 Baicalein
1 Sulfasalazine
1 Selenium
1 Selenium NanoParticles
1 Iron
1 Shikonin
1 Spermidine
1 Selenite (Sodium)
1 Thymoquinone
1 Urolithin
1 Vitamin D3
1 Whole Body Vibration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:961  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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