TumCP Cancer Research Results

TumCP, Tumor Cell proliferation: Click to Expand ⟱
Source:
Type:
Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors.


neuroblastoma, Neuroblastoma: Click to Expand ⟱
Neuroblastoma is a type of cancer that develops in immature nerve tissue, usually affecting kids under age 5.

Scientific Papers found: Click to Expand⟱
297- ALA,    Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
- Review, BC, SkBr3 - Review, neuroblastoma, SK-N-SH - Review, AD, NA
PDH↑, TumCG↓, ROS↑, AMPK↑, EGR4↓, Half-Life↓, BioAv↝, *GSH↑, *IronCh↑, *ROS↓, *antiOx↑, *neuroP↑, *Ach↑, *lipid-P↓, *IL1β↓, *IL6↓, TumCP↓, FDG↓, Apoptosis↑, AMPK↑, mTOR↓, EGFR↓, TumCI↓, TumCMig↓, *memory↑, *BioAv↑, *BioAv↝, *other↓, *other↝, *Half-Life↓, *BioAv↑, *ChAT↑, *GlucoseCon↑,
2685- BBR,    Berberine induces neuronal differentiation through inhibition of cancer stemness and epithelial-mesenchymal transition in neuroblastoma cells
- in-vitro, neuroblastoma, NA
CSCs↓, CD133↓, β-catenin/ZEB1↓, n-MYC↓, SOX2↓, NOTCH2↓, Nestin↓, TumCCA↑, TumCP↓, CDK1↓, Cyc↓, Apoptosis↑, Bax:Bcl2↑, NCAM↓, MMP2↓, MMP9↓, *Smad1↑, *HSP70/HSPA5↑, *LAMs↑,
5726- BF,    Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain
- Review, neuroblastoma, SK-N-BE
Apoptosis↑, TumCP↓, TumCMig↓, MMP↓, ROS↑, ETC↓, Bcl-2↓, BAX↑, cl‑Casp3↑, cl‑PARP↑, eff↓, TumCG↓, Ki-67↓, PCNA↓,
7345- Hne,    A root extract of Helleborus niger possess cytotoxic properties in neuroblastoma cells
- in-vitro, neuroblastoma, NXS2
TumCP↓, Casp8↑, Casp9↑, Ca+2↑,
6811- RF,    Continuous Exposure to 1.7 GHz LTE Electromagnetic Fields Increases Intracellular Reactive Oxygen Species to Decrease Human Cell Proliferation and Induce Senescence
- in-vitro, Liver, HUH7 - in-vitro, Liver, Hep3B - in-vitro, Cerv, HeLa - in-vitro, neuroblastoma, SH-SY5Y - in-vitro, Nor, IMR90
TumCP↓, eff↑, ROS↑, eff↓,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

ROS↑, 3,  

Mitochondria & Bioenergetics(tgid=3)

ETC↓, 1,   MMP↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

AMPK↑, 2,   FDG↓, 1,   PDH↑, 1,  

Cell Death(tgid=5)

Apoptosis↑, 3,   BAX↑, 1,   Bax:Bcl2↑, 1,   Bcl-2↓, 1,   cl‑Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 1,  

DNA Damage & Repair(tgid=10)

cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11)

CDK1↓, 1,   Cyc↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

CD133↓, 1,   CSCs↓, 1,   mTOR↓, 1,   n-MYC↓, 1,   Nestin↓, 1,   NOTCH2↓, 1,   SOX2↓, 1,   TumCG↓, 2,  

Migration(tgid=13)

Ca+2↑, 1,   Ki-67↓, 1,   MMP2↓, 1,   MMP9↓, 1,   NCAM↓, 1,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 5,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

EGFR↓, 1,   EGR4↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↝, 1,   eff↓, 2,   eff↑, 1,   Half-Life↓, 1,  

Clinical Biomarkers(tgid=22)

EGFR↓, 1,   Ki-67↓, 1,  
Total Targets: 43

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   GSH↑, 1,   lipid-P↓, 1,   ROS↓, 1,  

Metal & Cofactor Biology(tgid=2)

IronCh↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

GlucoseCon↑, 1,  

Transcription & Epigenetics(tgid=7)

Ach↑, 1,   other↓, 1,   other↝, 1,  

Protein Folding & ER Stress(tgid=8)

HSP70/HSPA5↑, 1,  

Migration(tgid=13)

LAMs↑, 1,   Smad1↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

IL1β↓, 1,   IL6↓, 1,  

Synaptic & Neurotransmission(tgid=18)

ChAT↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 2,   BioAv↝, 1,   Half-Life↓, 1,  

Clinical Biomarkers(tgid=22)

IL6↓, 1,  

Functional Outcomes(tgid=23)

memory↑, 1,   neuroP↑, 1,  
Total Targets: 21

Scientific Paper Hit Count for: TumCP, Tumor Cell proliferation
1 Alpha-Lipoic-Acid
1 Berberine
1 Bufalin/Huachansu
1 Helleborus niger extracts – Christmas Rose
1 EMF
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:40  Cells:%  prod#:%  Target#:327  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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