MDA Cancer Research Results

MDA, Serum malondialdehyde: Click to Expand ⟱
Source:
Type:
MDA : malondialdehyde. The level of oxidative stress can be measured by assessing the MDA levels.
Since MDA is highly cytotoxic and carcinogenic agent it is frequently used as a biomarker of oxidative stress during major health problems such as cancer, etc.
Malondialdehyde (MDA) is the most widely used agent to estimate the extent of lipid peroxidation. Timely diagnosis of the condition followed by supplementation with antioxidants like beta-carotene, pro-vitamin A, vitamin A, vitamin C, vitamin E, lipoic acid, zinc, selenium, and spirulina can prevent potentially malignant disorders.
MDA is a lipid peroxidation marker


neuroblastoma, Neuroblastoma: Click to Expand ⟱
Neuroblastoma is a type of cancer that develops in immature nerve tissue, usually affecting kids under age 5.

Scientific Papers found: Click to Expand⟱
8039- IVM,    Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy
- NA, neuroblastoma, SH-SY5Y
*toxicity↑, TumCD↑, ROS↑, mtDam↑, Apoptosis↑, MitoP↑, TumAuto↑, p‑Akt↓, p‑mTOR↓, LC3II↑, Beclin-1/ATG6↑, ATG5↑, PINK1↑, PARK2↑, tumCV↓, MDA↑, SOD↑, Catalase↑, eff↓, MMP↓, BAX↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, Cyt‑c↑, Bcl-2↓, proCasp3↓, Bax:Bcl2↑, eff↑, *AntiP↑, *Inflam↓, *AntiDiabetic↑, *AntiViral↑, BBB∅, toxicity↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

Catalase↑, 1,   MDA↑, 1,   PARK2↑, 1,   ROS↑, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↓, 1,   mtDam↑, 1,   PINK1↑, 1,  

Cell Death(tgid=5)

p‑Akt↓, 1,   Apoptosis↑, 1,   BAX↑, 1,   Bax:Bcl2↑, 1,   Bcl-2↓, 1,   cl‑Casp3↑, 1,   proCasp3↓, 1,   cl‑Casp9↑, 1,   Cyt‑c↑, 1,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7)

tumCV↓, 1,  

Autophagy & Lysosomes(tgid=9)

ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3II↑, 1,   MitoP↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10)

cl‑PARP↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

p‑mTOR↓, 1,  

Barriers & Transport(tgid=15)

BBB∅, 1,  

Drug Metabolism & Resistance(tgid=21)

eff↓, 1,   eff↑, 1,  

Functional Outcomes(tgid=23)

toxicity↝, 1,  
Total Targets: 30

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiP↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 1,  

Functional Outcomes(tgid=23)

AntiDiabetic↑, 1,   toxicity↑, 1,  

Infection & Microbiome(tgid=24)

AntiViral↑, 1,  
Total Targets: 5

Scientific Paper Hit Count for: MDA, Serum malondialdehyde
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:40  Cells:%  prod#:%  Target#:570  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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