tumCV Cancer Research Results

tumCV, Cell Viability: Click to Expand ⟱
Source:
Type:
Cell Viability
Thyroid, Thyroid: Click to Expand ⟱
Thyroid


Scientific Papers found: Click to Expand⟱
5826- CAP,    Capsaicin induces mitochondrial dysfunction and apoptosis in anaplastic thyroid carcinoma cells via TRPV1-mediated mitochondrial calcium overload
- in-vitro, Thyroid, NA
TRPV1↑, tumCV↓, Ca+2↑, mtDam↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, Apoptosis↑,
2384- MET,    Integration of metabolomics and transcriptomics reveals metformin suppresses thyroid cancer progression via inhibiting glycolysis and restraining DNA replication
- in-vitro, Thyroid, BCPAP - in-vivo, NA, NA - in-vitro, Thyroid, TPC-1
Glycolysis↓, OXPHOS↑, tumCV↓, TumCI↓, TumCMig↓, EMT↓, Apoptosis↑, TumCCA↑, LDHA↓, PKM2↓, IDH1↑, TumCG↓,
2944- PL,    Piperlongumine, a Potent Anticancer Phytotherapeutic, Induces Cell Cycle Arrest and Apoptosis In Vitro and In Vivo through the ROS/Akt Pathway in Human Thyroid Cancer Cells
- in-vitro, Thyroid, IHH4 - in-vitro, Thyroid, 8505C - in-vivo, NA, NA
ROS↑, selectivity↑, tumCV↓, TumCCA↑, Apoptosis↑, ERK↑, Akt↓, mTOR↓, neuroP↑, Bcl-2↓, Casp3↑, PARP↑, JNK↑, *toxicity↓, eff↓, TumW↓,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

OXPHOS↑, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,   MPT↑, 1,   mtDam↑, 1,  

Core Metabolism/Glycolysis ⓘ

Glycolysis↓, 1,   IDH1↑, 1,   LDHA↓, 1,   PKM2↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↑, 3,   Bcl-2↓, 1,   Casp↑, 1,   Casp3↑, 1,   Cyt‑c↑, 1,   JNK↑, 1,   TRPV1↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 3,  

DNA Damage & Repair ⓘ

PARP↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 2,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   ERK↑, 1,   mTOR↓, 1,   TumCG↓, 1,  

Migration ⓘ

Ca+2↑, 1,   TumCI↓, 1,   TumCMig↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↓, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

neuroP↑, 1,   TumW↓, 1,  
Total Targets: 31

Pathway results for Effect on Normal Cells:


Functional Outcomes ⓘ

toxicity↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: tumCV, Cell Viability
1 Capsaicin
1 Metformin
1 Piperlongumine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:43  Cells:%  prod#:%  Target#:897  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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