MMP13 Cancer Research Results

MMP13, MMP13: Click to Expand ⟱
Source:
Type:
MMP-13, or matrix metalloproteinase-13, is an enzyme that plays a significant role in the degradation of extracellular matrix components. It is involved in various physiological processes, including tissue remodeling, wound healing, and bone development.
MMP-13 is often overexpressed in various types of cancers, including breast, colorectal, and lung cancers.
OS, Osteosarcoma: Click to Expand ⟱
Osteosarcoma is a type of cancer that starts in the bones. It is the most common type of bone cancer, and it usually affects children and young adults, although it can occur at any age. Osteosarcoma typically develops in the long bones of the body, such as the arms and legs, but it can also occur in other bones, including the pelvis and jaw.
Scientific Papers found: Click to Expand⟱
2971- PL,    Piperlongumine attenuates IL-1β-induced inflammatory response in chondrocytes
- NA, OS, NA
*NO↓, *PGE2↓, *iNOS↓, *COX2↓, *MMP3↑, *MMP13↓, *Inflam↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Cell Death ⓘ

iNOS↓, 1,  

Migration ⓘ

MMP13↓, 1,   MMP3↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   Inflam↓, 1,   PGE2↓, 1,  
Total Targets: 7

Scientific Paper Hit Count for: MMP13, MMP13
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:46  Cells:%  prod#:%  Target#:199  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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