MALAT1 Cancer Research Results

MALAT1, Metastasis Associated Lung Adenocarcinoma Transcript 1: Click to Expand ⟱
Source:
Type:
MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) is a long non-coding RNA (lncRNA) that has been implicated in various types of cancer, including lung cancer, breast cancer, and colorectal cancer.
MALAT1 is often overexpressed in cancer tissues compared to normal tissues. Its expression levels have been correlated with tumor progression, metastasis, and poor prognosis in several cancers. It has been shown to promote the metastatic potential of cancer cells by regulating epithelial-mesenchymal transition (EMT) and enhancing cell migration and invasion.
OS, Osteosarcoma: Click to Expand ⟱
Osteosarcoma is a type of cancer that starts in the bones. It is the most common type of bone cancer, and it usually affects children and young adults, although it can occur at any age. Osteosarcoma typically develops in the long bones of the body, such as the arms and legs, but it can also occur in other bones, including the pelvis and jaw.
Scientific Papers found: Click to Expand⟱
2648- AL,    Allicin Inhibits Osteosarcoma Growth by Promoting Oxidative Stress and Autophagy via the Inactivation of the lncRNA MALAT1-miR-376a-Wnt/β-Catenin Signaling Pathway
- in-vitro, OS, SaOS2 - in-vivo, OS, NA
ROS↑, TumCG↓, TumAuto↑, Wnt↓, β-catenin/ZEB1↓, MALAT1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,   Wnt↓, 1,  

Migration ⓘ

MALAT1↓, 1,   β-catenin/ZEB1↓, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MALAT1, Metastasis Associated Lung Adenocarcinoma Transcript 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:46  Cells:%  prod#:%  Target#:493  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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