SSBP1 Cancer Research Results

SSBP1, single-stranded DNA binding protein 1: Click to Expand ⟱

Source:

Type:

<span class="wphighlight">SSBP1</span> (Single-Stranded DNA-Binding Protein 1) and Cancer — Mitochondrial Genome Stability, Metabolic Fitness, and Stress Tolerance<br>
<b>While many studies</b> suggest that altered <span class="wphighlight">SSBP1</span> expression is linked to tumor aggressiveness and patient outcomes, the direction of change (upregulation or downregulation) and the prognostic implications can vary between cancer types. For instance:<br>
<br>
• In breast and colorectal cancers, lower <span class="wphighlight">SSBP1</span> expression has been associated with enhanced invasiveness and poorer prognosis.<br>
<br>
• In lung cancer, higher <span class="wphighlight">SSBP1</span> expression in some studies correlates with more aggressive disease features and unfavorable outcomes.<br>

OS, Osteosarcoma: Click to Expand ⟱

Osteosarcoma is a type of cancer that starts in the bones. It is the most common type of bone cancer, and it usually affects children and young adults, although it can occur at any age. Osteosarcoma typically develops in the long bones of the body, such as the arms and legs, but it can also occur in other bones, including the pelvis and jaw.

Scientific Papers found: Click to Expand⟱

1208-

SANG,

Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3 to the single-stranded DNA-binding protein 1 (SSBP1) promoter region

in-vitro,

OS,

SSBP1↑, mtDam↑, Apoptosis↑, JAK↓, STAT3↓, PI3k/Akt/mTOR↓, ROS↑, MMP↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Immune & Inflammatory Signaling ⓘ

JAK↓, 1,
Total Targets: 8

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: SSBP1, single-stranded DNA binding protein 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:46  Cells:%  prod#:%  Target#:1047  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

SSBP1 Cancer Research Results

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

Mitochondria & Bioenergetics ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Proliferation, Differentiation & Cell State ⓘ

Immune & Inflammatory Signaling ⓘ

Pathway results for Effect on Normal Cells:

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