CXCR2 Cancer Research Results
CXCR2, CXCR2: Click to Expand ⟱
| Source: |
| Type: chemokine receptor |
CXCR2 is a chemokine receptor that plays a crucial role in the progression and metastasis of various types of cancer.
CXCR2 is often over expression and is associated with poor prognosis and increased risk of metastasis.
Several CXCR2 inhibitors, such as SB225002 and AZD5069, have been developed and are being evaluated in preclinical and clinical studies for their potential to treat various types of cancer.
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OS, Osteosarcoma: Click to Expand ⟱
Osteosarcoma is a type of cancer that starts in the bones. It is the most common type of bone cancer, and it usually affects children and young adults, although it can occur at any age. Osteosarcoma typically develops in the long bones of the body, such as the arms and legs, but it can also occur in other bones, including the pelvis and jaw.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
OS, |
U2OS |
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in-vitro, |
Lung, |
A549 |
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TumCCA↑, ROS↑, γH2AX↑, ATM↑, p‑CHK1↑, cellSen↑, CXCR2↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
DNA Damage & Repair ⓘ
ATM↑, 1, p‑CHK1↑, 1, γH2AX↑, 1,
Cell Cycle & Senescence ⓘ
TumCCA↑, 1,
Immune & Inflammatory Signaling ⓘ
cellSen↑, 1, CXCR2↑, 1,
Total Targets: 7
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: CXCR2, CXCR2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:46 Cells:% prod#:% Target#:921 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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