Weight Cancer Research Results

Weight, Weight: Click to Expand ⟱
Source:
Type:
Weight


OS, Osteosarcoma: Click to Expand ⟱
Osteosarcoma is a type of cancer that starts in the bones. It is the most common type of bone cancer, and it usually affects children and young adults, although it can occur at any age. Osteosarcoma typically develops in the long bones of the body, such as the arms and legs, but it can also occur in other bones, including the pelvis and jaw.


Scientific Papers found: Click to Expand⟱
1483- SFN,    Targeting p62 by sulforaphane promotes autolysosomal degradation of SLC7A11, inducing ferroptosis for osteosarcoma treatment
- in-vitro, OS, 143B - in-vitro, Nor, HEK293 - in-vivo, OS, NA
AntiCan↑, *toxicity∅, Ferroptosis↑, ROS↑, lipid-P↑, GSH↓, p62↑, SLC12A5↓, eff↓, GPx4↓, i-Iron↑, eff↓, MDA↑, TumVol↓, TumW↓, Ki-67↓, LC3B↑, *Weight∅,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

Ferroptosis↑, 1,   GPx4↓, 1,   GSH↓, 1,   i-Iron↑, 1,   lipid-P↑, 1,   MDA↑, 1,   ROS↑, 1,  

Cell Death

Ferroptosis↑, 1,  

Autophagy & Lysosomes

LC3B↑, 1,   p62↑, 1,  

Migration

Ki-67↓, 1,  

Barriers & Transport

SLC12A5↓, 1,  

Drug Metabolism & Resistance

eff↓, 2,  

Clinical Biomarkers

Ki-67↓, 1,  

Functional Outcomes

AntiCan↑, 1,   TumVol↓, 1,   TumW↓, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Functional Outcomes

toxicity∅, 1,   Weight∅, 1,  
Total Targets: 2

Scientific Paper Hit Count for: Weight, Weight
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:46  Cells:%  prod#:%  Target#:603  State#:%  Dir#:6
wNotes=0 sortOrder:rid,rpid

 

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