Database Query Results : , ,

CKD, Chronic Kidney Disease: Click to Expand ⟱

Chronic Kidney Disease

Scientific Papers found: Click to Expand⟱

HNK,

Honokiol attenuates oxidative stress and vascular calcification via the upregulation of heme oxygenase-1 in chronic kidney disease

in-vitro,

CKD,

*HO-1↑, *ROS↓,

2363-

SK,

Inhibition of PKM2 by shikonin impedes TGF-β1 expression by repressing histone lactylation to alleviate renal fibrosis

in-vivo,

CKD,

mice

PKM2↓, lactateProd↓, TGF-β↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:

Core Metabolism/Glycolysis ⓘ

lactateProd↓, 1, PKM2↓, 1,

Migration ⓘ

TGF-β↓, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

HO-1↑, 1, ROS↓, 1,
Total Targets: 2

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells