hepatoP Cancer Research Results

hepatoP, L,hepatoprotective: Click to Expand ⟱
Source:
Type:
Hepatoprotective is the ability of a chemical substance to prevent damage to the liver.

Grapefruit:
-hepatoprotective potential has emerged from the study of naringenin and naringin.
Blueberries/cranberries:
-proanthocyanidins
Grape:
Nopal (Cactus pear) and tuna (Cactus pear fruit) “Opuntia ficus-indica”:
Chamomile (Matricaria chamomilla or Chamomilla recutita):
Silymarin (Silybum marianum):
Blue green algae spirulina :
Propolis (bee glue):

POLYSACCHARIDES
β-glucans
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
6699- DFC,    Mitochondrial H2O2 Is a Central Mediator of Diclofenac-Induced Hepatocellular Injury
- vitro+vivo, Nor, NA
*ROS↑, *hepatoP↓, *eff↑, *ATP↓, OXPHOS↓, *ETC↓, *compI↓, *compIII↓,
6781- EGCG,    Scientific opinion on the safety of green tea catechins
- Review, Nor, NA
*hepatoP↓, *Dose↝, *ALAT↑, *AST↑,
7803- IBC,    Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc--GSH-GPX4 signaling pathway in ferroptosis response
- in-vivo, Nor, NA - in-vitro, NA, HepG2
*hepatoP↓, *ALAT↑, *AST↑, *ROS↑, *MDA↑, *Catalase↓, *GSH↓, *GPx↓, *i-Iron↑,
7804- IBC,    Isobavachalcone: A comprehensive review of its plant sources, pharmacokinetics, toxicity, pharmacological activities and related molecular mechanisms
- Review, Nor, NA
*BioAv↓, *BBB↑, *hepatoP↓, ROS↑, *NA↓, ERK↓, Wnt↓, Apoptosis↑, *NF-kB↓, *NRF2↑, *HO-1↑, *Inflam↓,
7805- IBC,    The enhanced hepatotoxicity of isobavachalcone in depigmented zebrafish due to calcium signaling dysregulation and lipid metabolism disorder
- in-vivo, Nor, NA
*hepatoP↓, *ROS↑, *Ca+2↝,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

OXPHOS↓, 1,   ROS↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,   Wnt↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 1,   compI↓, 1,   GPx↓, 1,   GSH↓, 1,   HO-1↑, 1,   i-Iron↑, 1,   MDA↑, 1,   NRF2↑, 1,   ROS↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   compIII↓, 1,   ETC↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↑, 2,  

Migration(tgid=13) ⓘ

Ca+2↝, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   Dose↝, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↑, 2,   AST↑, 2,  

Functional Outcomes(tgid=23) ⓘ

hepatoP↓, 5,  
Total Targets: 24

Scientific Paper Hit Count for: hepatoP, L,hepatoprotective
3 Isobavachalcone
1 Diclofenac
1 EGCG (Epigallocatechin Gallate)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:1179  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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