Aβ Cancer Research Results
Aβ, Aβ aggregation: Click to Expand ⟱
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| Type: |
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
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Nor, Normal Healthy: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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Review, |
Nor, |
NA |
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Review, |
Stroke, |
NA |
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Review, |
AD, |
NA |
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*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *eff↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp↓, eff↑, other↝,
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Review, |
Nor, |
NA |
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Review, |
AD, |
NA |
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*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
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Review, |
Nor, |
NA |
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- |
Review, |
Stroke, |
NA |
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Review, |
Park, |
NA |
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*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
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in-vivo, |
AD, |
NA |
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in-vitro, |
Nor, |
PC12 |
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*cognitive↑, *p‑PI3K↓, *p‑Akt↓, *AMPK↑, *VDAC1↓, *neuroP↑, *PARK2↑, *PTEN↑, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p62↓, *Aβ↓, *Apoptosis↓,
Showing Research Papers: 1 to 4 of 4
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSTs↑, 1, HO-1↑, 1, NADH↓, 1, NRF2↑, 1, ROS↑, 1,
Mitochondria & Bioenergetics ⓘ
MMP↓, 1, MPT↑, 1,
Core Metabolism/Glycolysis ⓘ
SIRT1↓, 1,
Cell Death ⓘ
Apoptosis↑, 1, Casp↑, 1, Cyt‑c↑, 1, p38↑, 1,
Transcription & Epigenetics ⓘ
other↝, 1,
Proliferation, Differentiation & Cell State ⓘ
TOP1↓, 1, TOP2↓, 1, TumCG↓, 1,
Migration ⓘ
TRIB3↑, 1, TumCMig↓, 1, β-catenin/ZEB1↓, 1,
Barriers & Transport ⓘ
BBB↑, 1, P-gp↓, 1,
Immune & Inflammatory Signaling ⓘ
IL1β↓, 1, NF-kB↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↝, 1, ChemoSen↑, 1, eff↑, 1,
Clinical Biomarkers ⓘ
TRIB3↑, 1,
Functional Outcomes ⓘ
cognitive↑, 1, Obesity↓, 1, toxicity↓, 1,
Total Targets: 30
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 2, Catalase↑, 1, GSH↑, 1, lipid-P↓, 1, PARK2↑, 1, ROS↓, 2, SOD↑, 2, VDAC1↓, 1,
Core Metabolism/Glycolysis ⓘ
12LOX↓, 1, AMPK↑, 1,
Cell Death ⓘ
p‑Akt↓, 1, Apoptosis↓, 1, TRPV1↑, 1,
Autophagy & Lysosomes ⓘ
LC3‑Ⅱ/LC3‑Ⅰ↑, 1, p62↓, 1,
Proliferation, Differentiation & Cell State ⓘ
p‑PI3K↓, 1, PTEN↑, 1,
Migration ⓘ
Ca+2↑, 1,
Angiogenesis & Vasculature ⓘ
EPR↑, 1, NO↓, 1, NO↑, 1,
Barriers & Transport ⓘ
BBB↓, 1, BBB↑, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, IL6↓, 1, IL6↑, 1, Inflam↓, 3, TNF-α↓, 2,
Synaptic & Neurotransmission ⓘ
BDNF↑, 1,
Protein Aggregation ⓘ
Aβ↓, 4,
Drug Metabolism & Resistance ⓘ
BioAv↓, 1, BioAv↑, 1, BioAv↝, 1, eff↑, 3, Half-Life↓, 1,
Clinical Biomarkers ⓘ
GutMicro↑, 1, IL6↓, 1, IL6↑, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, cardioP↑, 1, cognitive↑, 1, neuroP↑, 4, toxicity↑, 1,
Infection & Microbiome ⓘ
Bacteria↓, 1,
Total Targets: 44
Scientific Paper Hit Count for: Aβ, Aβ aggregation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:49 Cells:% prod#:% Target#:1333 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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