ATG3 Cancer Research Results

ATG3, Autophagy-related 3: Click to Expand ⟱

Source:

Type: protein

ATG3 (Autophagy-related 3) is a protein that plays a crucial role in the process of autophagy, a cellular mechanism that involves the degradation and recycling of damaged or dysfunctional cellular components. ATG3 is involved in the regulation of autophagy.
Increased expression in: breast, lung, GBM, ovarian, prostate, panreatic, hepatocellar.
Decreased expression in: colon (associated with improved prognosis).

Nor, Normal Healthy: Click to Expand ⟱

Normal Healthy

Scientific Papers found: Click to Expand⟱

4735-

SeNPs,

Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum

in-vivo,

Nor,

rabbits + Cd.

*MDA↓, *H2O2↓, *Catalase↑, *SOD↑, *GSTs↑, *GSH↑, *NRF2↓, *ATG3↓, *AMPK↓, *ROS↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

Catalase↑, 1, GSH↑, 1, GSTs↑, 1, H2O2↓, 1, MDA↓, 1, NRF2↓, 1, ROS↓, 1, SOD↑, 1,

Core Metabolism/Glycolysis ⓘ

AMPK↓, 1,

Autophagy & Lysosomes ⓘ

ATG3↓, 1,
Total Targets: 10

Scientific Paper Hit Count for: ATG3, Autophagy-related 3

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells