mPGES-1 Cancer Research Results

mPGES-1, Microsomal prostaglandin E synthase-1: Click to Expand ⟱
Source:
Type:
Microsomal prostaglandin E synthase-1 (mPGES-1) is an enzyme involved in the production of prostaglandin E2 (PGE2), a pro-inflammatory mediator that plays a role in various physiological and pathological processes, including cancer.
Expression is high in cancers and associated with poor prognosis and lower OS.
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
3499- MFrot,  MF,    Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans
- in-vitro, Nor, HUVECs
*AntiAge↑, *AMPK↑, *mPGES-1↓, *Ca+2↑, *ER Stress↑, *OS↑, *ROS↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

ROS↓, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↑, 1,  

Migration ⓘ

Ca+2↑, 1,  

Immune & Inflammatory Signaling ⓘ

mPGES-1↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 1,   OS↑, 1,  
Total Targets: 7

Scientific Paper Hit Count for: mPGES-1, Microsomal prostaglandin E synthase-1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:899  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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