Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.


Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy

Scientific Papers found: Click to Expand⟱
6477- 1,8-Cin,    Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling
- in-vivo, Nor, NA
*MDA↓, *GSH↑, *GPx↑, *Inflam↓, *TLR4↓, *MyD88↓, *NF-kB↓, *AST↓, *ALAT↓, *hepatoP↑, *ROS↓,
6474- 1,8-Cin,    Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation
- in-vitro, Nor, HT29 - in-vivo, Nor, NA - in-vivo, IBD, NA
*Inflam↓, *NRF2↑, *antiOx↑, *PPARγ↑, eff↑,
6472- 1,8-Cin,    Protective Effects of 1,8-Cineole Microcapsules Against Inflammation and Gut Microbiota Imbalance Associated Weight Loss Induced by Heat Stress in Broiler Chicken
- in-vivo, Nor, NA
*Inflam↓, *GutMicro↑,
2326- 2DG,    Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury via Suppressing Nuclear Pyruvate Kinase M2–Signal Transducer and Activator of Transcription 3 Pathway
- in-vivo, Nor, NA
PKM2↓, Inflam↓, TNF-α↓, IL6↓, OS↑,
7980- AAS/EEAA,    Protective Effects of Annona Atemoya Extracts on Inflammation, Oxidative Stress, and Renal Function in Cadmium-Induced Nephrotoxicity in Wistar Rats
- in-vivo, Nor, NA
*creat↓, *SOD↑, *Catalase↑, *GPx↑, *TNF-α↓, *IL6↓, *RenoP↑, *Inflam↓, *ROS↓,
4360- AgNPs,    Silver Nanoparticles as Real Topical Bullets for Wound Healing
- Study, Nor, NA
*other↝, *toxicity↓, *eff↑, *eff↑, *Inflam↓, *IL6↓, *TGF-β↑, *MMP9↓, *eff↑,
4434- AgNPs,  SSE,    Sodium Selenite Ameliorates Silver Nanoparticles Induced Vascular Endothelial Cytotoxic Injury by Antioxidative Properties and Suppressing Inflammation Through Activating the Nrf2 Signaling Pathway
- vitro+vivo, Nor, NA
*ROS↓, *Inflam↓, *NLRP3↓, *NF-kB↓, *NRF2↑, *HO-1↑, *toxicity↓,
4447- AgNPs,    Anti-inflammatory action of silver nanoparticles in vivo: systematic review and meta-analysis
- Review, Nor, NA
*Inflam↓, *COX2/PTGS2↓, *ROS↓, *Dose↝, *eff↑, *toxicity↓, *IL4↑, *IL5↑, *IL10↑, *IL1↓, *IL6↓, *TNF-α↓, *NF-kB↓, *MDA↓, *GSH↑,
2206- AgNPs,  RES,    ENHANCED EFFICACY OF RESVERATROL-LOADED SILVER NANOPARTICLE IN ATTENUATING SEPSIS-INDUCED ACUTE LIVER INJURY: MODULATION OF INFLAMMATION, OXIDATIVE STRESS, AND SIRT1 ACTIVATION
- in-vivo, Nor, NA
*hepatoP↑, *Inflam↓, *NF-kB↓, *VEGF↓, *SIRT1↑, *ROS↓, *Dose↝, *Catalase↑, *MDA↓, *MPO↓, *NO↓, *ALAT↓, *AST↓, *antiOx↑,
6763- AL,    Revealing the Therapeutic Uses of Garlic (Allium sativum) and Its Potential for Drug Discovery
- Review, Nor, NA
*Inflam↓, *AntiBio↑, *AntiDiabetic↑, *hepatoP↑, *antiOx↑, *AntiFungal↑, *Wound Healing↑, *other↑, *BP↓, *LDL↓, *AntiAg↑, *cognitive↑, *memory↑, Risk↑, *COX1↓, *TXA2↓,
7407- Amla,    Functional and Nutraceutical Significance of Amla (Phyllanthus emblica L.): A Review
- Review, Nor, NA
*Inflam↓, *antiOx↑, *GSH↑, *GPx↑, *SOD↑, *Catalase↑, *lipid-P↓, *ROS↓, *cardioP↑, *AntiDiabetic↑, *neuroP↑, *GastroP↑, *COX2/PTGS2↓, *MDA↓, *BAX↓, *TG/TAG↓, *HDL↑, *LDL↓, *HMG-CoA↓, *Dose↝, *CRP↓, DNAdam↑, Casp3↑, Casp7↑, Casp8↑, Fas↑, TumCI↓, selectivity↑,
6402- ANE,  FEO,    trans-Anethole of Fennel Oil is a Selective and Nonelectrophilic Agonist of the TRPA1 Ion Channel
- in-vitro, Nor, HEK293
*TRPA1↑, *Dose↝, *Bacteria↓, *Inflam↓,
2318- Api,    Apigenin as a multifaceted antifibrotic agent: Therapeutic potential across organ systems
- Review, Nor, NA
*ROS↓, *PKM2↓, *Hif1a↓, *TGF-β↓, *AMPK↑, *Inflam↓, *PI3K↓, *Akt↑, *NRF2↑, *NF-kB↓,
3392- ART/DHA,    Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways
- in-vitro, Nor, Hep3B - in-vivo, NA, NA
*Inflam↓, *NF-kB↓, *ROS↓, *p‑p38↓, *p‑ERK↓,
5400- ASA,    Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention
- Review, Nor, NA
Risk↓, *Inflam↓, *COX1↓, *AntiAg↑, *Half-Life↓, *BioAv↑,
3165- Ash,    Inhibitory effect of withaferin A on Helicobacter pylori‑induced IL‑8 production and NF‑κB activation in gastric epithelial cells
- in-vitro, Nor, NA
*IL8↓, *Inflam↓,
5174- Ash,    Withaferin A is a potent inhibitor of angiogenesis
- in-vitro, Nor, HUVECs
Inflam↓, *TumCP↓, cycD1/CCND1↓, NF-kB↓, angioG↓,
4824- ASTX,  Rad,    Astaxanthin protects the radiation-induced lung injury in C57BL/6 female mice
- in-vivo, Nor, NA
*radioP↑, Inflam↓,
4818- ASTX,  MEL,    Effect of astaxanthin and melatonin on cell viability and DNA damage in human breast cancer cell lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, T47D - in-vitro, Nor, MCF10
TumCD↑, DNAdam↑, *antiOx↑, *AntiTum↑, Inflam↓, tumCV↓, Bcl-2↓, Apoptosis↓, selectivity↑, eff↑, Dose↓,
5418- ASTX,    Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials
- Review, Nor, NA
*MDA↓, *SOD↑, *IL6↓, *ROS↓, *Inflam↓,
5419- ASTX,    Astaxanthin and other Nutrients from Haematococcus pluvialis—Multifunctional Applications
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↓, AntiCan↑, *lipid-P↓, TumCP↓, Apoptosis↑, TumCCA↑, *SOD↑, *PGE2↓, *NO↓, *IL8↓, *IFN-γ↓, *cardioP↑, *NF-kB↓, *TNF-α↓, *BioAv↑,
5365- AV,    Aloe Vera Polysaccharides as Therapeutic Agents: Benefits Versus Side Effects in Biomedical Applications
- Review, Nor, NA - Review, IBD, NA - Review, Diabetic, NA
*Wound Healing↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *AntiCan↑, *Inflam↓, *NF-kB↓, *COX2/PTGS2↓, *5LO↓, *IL1β↓, *IL6↓, *TNF-α↓, *IL10↑, *other↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *DNAdam↓, *GutMicro↑, *ZO-1↑, AntiTum↑, Casp3↑, Casp9↑, angioG↓, MMPs↓, VEGF↓, NK cell↑,
5506- Ba,    Improved Bioavailability and Hepatoprotective Activity of Baicalein Via a Self-assembled Solutol HS15 Micelles System
- in-vivo, Nor, NA
*AST↓, *ALAT↓, *GSH↓, *SOD↓, *MDA↓, *hepatoP↑, *Inflam↓, BioAv↑,
2607- Ba,  SIL,    Baicalein Enhances the Oral Bioavailability and Hepatoprotective Effects of Silybin Through the Inhibition of Efflux Transporters BCRP and MRP2
- in-vivo, Nor, NA
*BioEnh↑, *hepatoP↑, *antiOx↑, *Inflam↓,
2293- Ba,    Baicalein suppresses inflammation and attenuates acute lung injury by inhibiting glycolysis via HIF‑1α signaling
- in-vitro, Nor, MH-S - in-vivo, NA, NA
*Hif1a↓, *Glycolysis↓, *Inflam↓, *HK2↓, *PFK1↓, *PKM2↓,
2686- BBR,    Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
- Review, Nor, NA
Inflam↓, IL6↓, MCP1/CCL2↓, COX2/PTGS2↓, PGE2↓, MMP2↓, MMP9↓, DNAdam↑, eff↝, Telomerase↓, Bcl-2↓, AMPK↑, ROS↑, MMP↓, ATP↓, p‑mTORC1↓, p‑S6K↓, ERK↓, PI3K↓, PTEN↑, Akt↓, Raf↓, MEK↓, Dose↓, Dose↑, selectivity↑, TumCCA↑, eff↑, EGFR↓, Glycolysis↓, Dose?, p27/CDKN1B↑, CDK2↓, CDK4↓, cycD1/CCND1↓, cycE/CCNE↓, Bax:Bcl2↑, Casp3↑, Casp9↑, VEGFR2/KDR/Flk1↓, ChemoSen↑, eff↑, eff↑, PGE2↓, JAK2↓, STAT3↓, CXCR4↓, CCR7↓, uPA↓, CSCs↓, EMT↓, Diff↓, CD133↓, Nestin↓, n-MYC↓, NOTCH↓, SOX2↓, Hif1a↓, VEGF↓, RadioS↑,
6519- BCP,    beta-Caryophyllene: A Sesquiterpene with Countless Biological Properties
- Review, Nor, NA
*CB2 / CNR2↑, *Inflam↓, *iNOS↓, *IL1β↓, *IL6↓, *TNF-α↓, *NF-kB↓, *COX1↓, *COX2/PTGS2↓, *PPARα↑, *PPARγ↑, *BioEnh↑,
6517- BCP,    β-Caryophyllene Ameliorates Cyclophosphamide Induced Cardiac Injury: The Association of TLR4/NFκB and Nrf2/HO1/NQO1 Pathways
- in-vivo, Nor, NA
*cardioP↑, *lipid-P↓, *antiOx↑, *NRF2↑, *HO-1↑, *NQO1↑, *TLR4↓, *NF-kB↓, *Inflam↓, *Apoptosis↓,
6516- BCP,    β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain
- in-vivo, Nor, NA
*NP/CIPN↓, *Inflam↓, *CB2 / CNR2↑,
6510- BCP,  CBD,    Cannabidiol and Beta-Caryophyllene Combination Attenuates Diabetic Neuropathy by Inhibiting NLRP3 Inflammasome/NFκB through the AMPK/sirT3/Nrf2 Axis
- in-vivo, Nor, NA
*MMP↓, *ROS↑, *BloodF↑, *Pain↓, *antiOx↑, *Inflam↓, *AMPK↑, *SIRT3↑, *NRF2↑, *PINK1↑, *PARK2↑, *LC3B↑, *Beclin-1/ATG6↑, *TFAM↑, *NLRP3↓, *NF-kB↓, *COX2/PTGS2↓, *p62↓, *NP/CIPN↓,
6496- BCP,    β-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models
- vitro+vivo, CRC, HCT116 - in-vitro, Nor, HUVECs
angioG↓, VEGF↓, TumVol↓, Apoptosis↑, HSP60/HSPD1↓, HTRA↓, survivin↓, XIAP↓, P21↑, *toxicity↓, *neuroP↑, *ROS↓, *COX2/PTGS2↓, *Inflam↓, *cardioP↑, AntiCan↑, ChemoSen↑, ROS↑, MMP↑, Bax:Bcl2↑, TumCG↓,
6506- BCP,    Multi-Target Protective Effects of β-Caryophyllene (BCP) at the Intersection of Neuroinflammation and Neurodegeneration
- vitro+vivo, Nor, HMC3
*neuroP↑, *NF-kB↓, *SIRT1↑, *PGC-1α↓, *BDNF↓, *TNF-α↓, *IL6↓, *IL10↑, *Inflam↓,
2724- BetA,    Down-regulation of NOX4 by betulinic acid protects against cerebral ischemia-reperfusion in mice
- in-vivo, Nor, NA - in-vivo, Stroke, NA
AntiTum↑, *Inflam↓, *ROS↓, *NOX4↓, *Apoptosis↓, neuroP↑,
2749- BetA,    Anti-Inflammatory Activities of Betulinic Acid: A Review
- Review, Nor, NA
Inflam↓, *NO↓, *IL10↑, *ICAM-1↓, *VCAM-1↓, *E-sel↓, *NF-kB↓, *IKKα↓, *COX2/PTGS2↓, *PGE2↓, *IL1β↓, *IL6↓, *IL8↓, *IL12↓, *TNF-α↑, *HO-1↑, *IL10↑, *IL2↓, *IL17↓, *IFN-γ↓, *SOD↑, *GPx↑, *GSR↑, *MDA↓, *MAPK↓,
5482- BM,    Bacopa monnieri protects SH-SY5Y cells against tert-Butyl hydroperoxide-induced cell death via the ERK and PI3K pathways
- in-vitro, Nor, NA
*neuroP↑, *ERK↑, *Akt↑, *MAPK↑, *PI3K↑, *Inflam↓, antiOx↑,
5656- BNL,    Role of borneol as enhancer in drug formulation: A review
- Review, Nor, NA - Review, Stroke, NA - Review, AD, NA
*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *eff↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp/ABCB1↓, eff↑, other↝,
5669- BNL,    Comparison of pharmacological activity and safety of different stereochemical configurations of borneol: L-borneol, D-borneol, and synthetic borneol
- Review, Nor, NA - Review, AD, NA - Review, Stroke, NA
*eff↑, *eff↑, *toxicity↝, *Inflam↓, *Bacteria↓, *neuroP↑, *Half-Life↝, *BBB↑, *BioEnh↑, *P-gp/ABCB1↓, *CYP3A4↓, *ROS↓, *neuroP↑,
6549- BSB,    (-)-α-bisabolol prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice
- in-vivo, Nor, NA
*antiOx↑, Inflam↓, *Dose↝, *neuroP↑, *motorD↑, *memory↑, *MPO↓, *TNF-α↓, *iNOS↓,
6553- BSB,    Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms
- Review, Nor, NA
*ROS↓, *Inflam↓, *Inf↓, *neuroP↑, *RNS↓, *MDA↓, *GSH↑, *MPO↓, *SOD↑, *Catalase↑, *Bcl-2↑, *BAX↓, *P53↓, *APAF1↓, *Casp3↓, *Casp9↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2/PTGS2↓, *ERK↓, *JNK↓, *NF-kB↓, *p38↓, *cognitive↑, *BChE↓,
6556- BSB,    A Comprehensive Study of Therapeutic Applications of Chamomile
- Review, Nor, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiBio↑, *hepatoP↑, *AntiCan↑, *other↝, *toxicity↓, *Wound Healing↓, *Dose↝, *Dose↝, *eff↝, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *AST↓, *ALAT↓,
6557- BSB,    Alpha-bisabolol protects against neonatal asthma by suppressing airway inflammatory signaling
- in-vivo, Nor, NA
*ROS↓, *Inflam↓, *IL1β↓, *IL6↓, *IL8↓, *IL17↓, *CXCR4↓, *COX2/PTGS2↓, *TLR4↓, *NO↓, *MDA↓, *XO↓,
6560- BSB,  doxoR,    Α-Bisabolol, a Component of German Chamomile Tea Attenuates NLRP3 Inflammasome Mediated Pyroptosis, NF-ΚB/MAPK Signaling Activation and Apoptosis by Invoking NRF2 Mediated Antioxidant Defense Systems in Doxorubicin-Induced Liver Injury in Rats
- in-vivo, Nor, NA
*lipid-P↓, *antiOx↑, *Apoptosis↓, *Inflam↓,
8182- BSO,  LEC,    The Protecting Role of Black Seed Oil and Its Nano-Formulation in LPS-Induced Acute Kidney Injury in Mice: Evaluation of Oxidative Stress, Biochemical & Molecular Parameters
- in-vivo, Nor, NA
*Inflam↓, *ROS↓, *RenoP↑, *Dose↝,
7953- BuckWS,  RT,    Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
- Review, Nor, NA
*GastroP↑, *hepatoP↑, *AntiDiabetic↑, *Inflam↓, *BioAv↓, *LDL↓, *Fenton↓, *AGEs↓, *GSH↑, *Dose↝,
5735- Buty,    Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease
- Study, Nor, NA
*Inflam↓, GutMicro↑, Imm↑,
5755- CA,    Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture
- Review, Nor, NA
*Imm↑, *Inflam↓, *Bacteria↓, *eff↑, *ROS↓, *MDA↓, *Catalase↑, *GSH↑, *TAC↑, *NF-kB↓, *NLRP3↓, *eff↑, *AST↓, *ALAT↓, *SOD↑, *GSTA1↑,
5872- CA,    Nrf2/ARE-Mediated Antioxidant Actions of Pro-Electrophilic Drugs
- Review, Nor, NA
*NRF2↑, *GSH↑, *neuroP↑, *Inflam↓, *cardioP↑, *Obesity↓, *angioG↓, chemoP↑, *NF-kB↓,
5834- CAP,    Capsaicin and TRPV1: A Novel Therapeutic Approach to Mitigate Vascular Aging
- Study, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *TRPV1↑, *AMPK↑, *SIRT1↑, *NADPH↓, *ROS↓, *MAPK↓, *eNOS↑, *Wnt/(β-catenin)↓, RenoP↑,
5830- CAP,    Inhibition of pyroptosis and apoptosis by capsaicin protects against LPS-induced acute kidney injury through TRPV1/UCP2 axis in vitro
- in-vitro, Nor, HK-2
*IL1β↓, *IL18↓, *TRPV1↑, *ROS↓, *MMP↑, *Apoptosis↓, *RenoP↑, *Inflam↓, *UCPs↑,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,

Showing Research Papers: 1 to 50 of 267
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 267

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

HSP60/HSPD1↓, 1,   HTRA↓, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   NADH↓, 1,   ROS↑, 3,  

Mitochondria & Bioenergetics(tgid=3)

ATP↓, 1,   MEK↓, 1,   MMP↓, 2,   MMP↑, 1,   MPT↑, 1,   Raf↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

AMPK↑, 1,   Glycolysis↓, 1,   PKM2↓, 1,   p‑S6K↓, 1,   SIRT1↓, 1,  

Cell Death(tgid=5)

Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 3,   Bax:Bcl2↑, 2,   Bcl-2↓, 2,   Casp↑, 1,   Casp3↑, 3,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 2,   Cyt‑c↑, 1,   Fas↑, 1,   p27/CDKN1B↑, 1,   p38↑, 1,   survivin↓, 1,   Telomerase↓, 1,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7)

other↝, 1,   tumCV↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 3,  

Cell Cycle & Senescence(tgid=11)

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

CD133↓, 1,   CSCs↓, 1,   Diff↓, 1,   EMT↓, 1,   ERK↓, 1,   p‑mTORC1↓, 1,   n-MYC↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   PI3K↓, 1,   PTEN↑, 1,   SOX2↓, 1,   STAT3↓, 1,   TOP1↓, 1,   TOP2↓, 1,   TumCG↓, 2,  

Migration(tgid=13)

MMP2↓, 1,   MMP9↓, 1,   MMPs↓, 1,   TRIB3↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,   uPA↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 3,   EGFR↓, 1,   Hif1a↓, 1,   VEGF↓, 3,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

CCR7↓, 1,   COX2/PTGS2↓, 1,   CXCR4↓, 1,   IL6↓, 2,   Imm↑, 1,   Inflam↓, 7,   JAK2↓, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 1,   NK cell↑, 1,   PGE2↓, 2,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   ChemoSen↑, 3,   Dose?, 1,   Dose↓, 2,   Dose↑, 1,   eff↑, 6,   eff↝, 1,   RadioS↑, 1,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22)

EGFR↓, 1,   GutMicro↑, 1,   IL6↓, 2,   TRIB3↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   AntiTum↑, 2,   chemoP↑, 1,   neuroP↑, 1,   Obesity↓, 1,   OS↑, 1,   RenoP↑, 1,   Risk↓, 1,   Risk↑, 1,   toxicity↓, 1,   TumVol↓, 1,  
Total Targets: 111

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiBio↑, 2,   TRPA1↑, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 15,   Catalase↑, 6,   Fenton↓, 1,   GPx↑, 5,   GSH↓, 1,   GSH↑, 7,   GSR↑, 1,   GSTA1↑, 1,   HDL↑, 1,   HO-1↑, 3,   lipid-P↓, 5,   MDA↓, 10,   MPO↓, 3,   NOX4↓, 1,   NQO1↑, 1,   NRF2↑, 6,   PARK2↑, 1,   RNS↓, 1,   ROS↓, 21,   ROS↑, 1,   SIRT3↑, 1,   SOD↓, 1,   SOD↑, 9,   TAC↑, 1,   UCPs↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↓, 1,   MMP↑, 1,   PGC-1α↓, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ALAT↓, 5,   AMPK↑, 3,   CYP3A4↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   HMG-CoA↓, 1,   LDL↓, 3,   NADPH↓, 1,   PFK1↓, 1,   PKM2↓, 2,   PPARα↑, 1,   PPARγ↑, 2,   SIRT1↑, 3,  

Cell Death(tgid=5)

Akt↑, 2,   APAF1↓, 1,   Apoptosis↓, 4,   BAX↓, 2,   Bcl-2↑, 1,   Casp3↓, 1,   Casp9↓, 1,   iNOS↓, 3,   JNK↓, 1,   MAPK↓, 2,   MAPK↑, 1,   p38↓, 1,   p‑p38↓, 1,   TRPV1↑, 3,  

Transcription & Epigenetics(tgid=7)

other↓, 1,   other↑, 1,   other↝, 3,   TFAM↑, 1,  

Autophagy & Lysosomes(tgid=9)

Beclin-1/ATG6↑, 1,   LC3B↑, 1,   p62↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 1,   P53↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

ERK↓, 1,   ERK↑, 1,   p‑ERK↓, 1,   PI3K↓, 1,   PI3K↑, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13)

5LO↓, 1,   AntiAg↑, 2,   Ca+2↑, 1,   E-sel↓, 1,   MMP9↓, 1,   TGF-β↓, 1,   TGF-β↑, 1,   TumCP↓, 1,   VCAM-1↓, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   eNOS↑, 1,   EPR↑, 1,   Hif1a↓, 2,   NO↓, 5,   TXA2↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15)

BBB↓, 1,   BBB↑, 1,   GastroP↑, 2,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

CB2 / CNR2↑, 2,   COX1↓, 3,   COX2/PTGS2↓, 9,   CRP↓, 1,   CXCR4↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 2,   IKKα↓, 1,   IL1↓, 1,   IL10↑, 5,   IL12↓, 1,   IL17↓, 2,   IL18↓, 1,   IL1β↓, 6,   IL2↓, 1,   IL4↑, 1,   IL5↑, 1,   IL6↓, 12,   IL8↓, 4,   Imm↑, 2,   Inflam↓, 43,   MyD88↓, 1,   NF-kB↓, 16,   PGE2↓, 2,   TLR4↓, 3,   TNF-α↓, 10,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18)

BChE↓, 1,   BDNF↓, 1,  

Protein Aggregation(tgid=19)

AGEs↓, 1,   Aβ↓, 2,   NLRP3↓, 3,   XO↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 2,   BioAv↑, 3,   BioAv↝, 1,   BioEnh↑, 3,   Dose↝, 9,   eff↑, 10,   eff↝, 1,   Half-Life↓, 2,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22)

ALAT↓, 5,   AST↓, 5,   BloodF↑, 1,   BP↓, 1,   creat↓, 1,   CRP↓, 1,   GutMicro↑, 3,   IL6↓, 12,   TG/TAG↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 4,   AntiDiabetic↓, 1,   AntiDiabetic↑, 4,   AntiTum↑, 1,   cardioP↑, 6,   cognitive↑, 2,   hepatoP↑, 7,   memory↑, 2,   motorD↑, 1,   neuroP↑, 11,   NP/CIPN↓, 2,   Obesity↓, 1,   Pain↓, 1,   radioP↑, 1,   RenoP↑, 3,   toxicity↓, 5,   toxicity↝, 1,   Wound Healing↓, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24)

AntiFungal↑, 1,   Bacteria↓, 4,   Inf↓, 1,  
Total Targets: 167

Scientific Paper Hit Count for: Inflam, inflammation
9 Magnetic Fields
9 Quercetin
7 Thymoquinone
6 Beta-Caryophyllene
6 Capsaicin
6 EGCG (Epigallocatechin Gallate)
6 Fisetin
6 Ginger/6-Shogaol/Gingerol
6 Vitamin C (Ascorbic Acid)
5 Silver-NanoParticles
5 Resveratrol
5 Silymarin (Milk Thistle) silibinin
5 α-Bisabolol / Chamomile oil
5 Chlorogenic acid
5 Kaempferol
5 Licochalcone A
5 Lycopene
5 Propolis -bee glue
5 Sulforaphane (mainly Broccoli)
4 Astaxanthin
4 Radiotherapy/Radiation
4 Carvacrol
4 Emodin
4 Eugenol
4 Ferulic acid
4 Honokiol
4 isoorientin
4 Isovitexin
4 Selenium NanoParticles
3 1,8-Cineole
3 Baicalein
3 doxorubicin
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Carvone
3 diet Fermented Foods
3 Gallic acid
3 Hydrogen Gas
3 Magnetic Field Rotating
3 Piperlongumine
3 Shikonin
2 Ashwagandha(Withaferin A)
2 Betulinic acid
2 borneol
2 Rutin
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Chrysin
2 methotrexate
2 Crocetin
2 Curcumin
2 Diclofenac
2 Date Fruit Extract
2 D-limonene
2 Dandelion Root
2 Cisplatin
2 eicosapentaenoic acid
2 flavonoids
2 Formononetin
2 HydroxyCitric Acid
2 Hydroxycinnamic-acid
2 isoquercitrin
2 Lemongrass Extract/Citral
2 Rosmarinic acid
2 Turmerones
1 2-DeoxyGlucose
1 Annona atemoya Seed Extract
1 Selenite (Sodium)
1 Allicin (mainly Garlic)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Apigenin (mainly Parsley)
1 Artemisinin
1 Aspirin
1 Melatonin
1 Aloe anthraquinones
1 Berberine
1 Cannabidiol
1 Bacopa monnieri
1 Black Seed Oil/Nigella sativa
1 Lecithin
1 buckwheat sprouts
1 Butyrate
1 Caffeic acid
1 Carnosic acid
1 Thymol-Thymus vulgaris
1 Cat’s Claw
1 Celastrol
1 Centella asiatica / Gotu kola → asiaticoside
1 Chlorophyllin
1 Choline
1 Chyawanprash
1 Cinnamon
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 Cynaropicrin
1 Dihydrocaffeic Acid
1 Dipyridamole
1 Docosahexaenoic Acid
1 Eurycomanone
1 Evodiamine
1 Ascorbyl Palmitate
1 Fucoidan
1 Gamma-aminobutyric acid
1 Garcinol
1 Ginkgolic acids
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Genistein (soy isoflavone)
1 Germacranolide sesquiterpene lactone
1 Siegesbeckia glabrescens
1 Hops (Humulus lupulus)
1 Hyperoside
1 Indole-3-carbinol
1 Isobavachalcone
1 Inulin Prebiotic
1 Isoliquiritigenin
1 Juglone
1 Linalool
1 Luteolin
1 Magnolol
1 Methyl salicylate / Sweet Birch oil
1 Metformin
1 nicotinamide adenine dinucleotide
1 Neem
1 Nimbolide
1 Oregano
1 Pterostilbene
1 Sulfasalazine
1 Gold NanoParticles
1 Terpinen-4-ol / Tea Tree Oil
1 Terminalia bellirica
1 Aflavin-3,3′-digallate
1 Thyme
1 Urolithin
1 Vitamin K2
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:953  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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