antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
4541- AgNPs,  RosA,    Eco-friendly synthesis of silver nanoparticles: multifaceted antioxidant, antidiabetic, anticancer, and antimicrobial activities
- in-vitro, Nor, WI38 - in-vitro, BC, MDA-MB-231 - in-vitro, PC, PANC1
*antiOx↑, TumCD↓, selectivity↑,
2206- AgNPs,  RES,    ENHANCED EFFICACY OF RESVERATROL-LOADED SILVER NANOPARTICLE IN ATTENUATING SEPSIS-INDUCED ACUTE LIVER INJURY: MODULATION OF INFLAMMATION, OXIDATIVE STRESS, AND SIRT1 ACTIVATION
- in-vivo, Nor, NA
*hepatoP↑, *Inflam↓, *NF-kB↓, *VEGF↓, *SIRT1↑, *ROS↓, *Dose↝, *Catalase↑, *MDA↓, *MPO↓, *NO↓, *ALAT↓, *AST↓, *antiOx↑,
2205- AgNPs,    Potential protective efficacy of biogenic silver nanoparticles synthesised from earthworm extract in a septic mice model
- in-vivo, Nor, NA
*Dose↝, *eff↑, *RenoP↑, *antiOx↑, *MDA↓, *NO↓, *hepatoP↑, *toxicity↝, *GSH↑, *SOD↑, *GSTs↑, *Catalase↑,
5344- Ajoene,    Ajoene, a Stable Garlic By-Product, Has an Antioxidant Effect through Nrf2-Mediated Glutamate-Cysteine Ligase Induction in HepG2 Cells and Primary Hepatocytes
- in-vitro, Nor, HepG2
*Nrf1↑, *PKCδ↑, *GSH↑, *antiOx↑,
2770- AL,    Allicin protects against renal ischemia–reperfusion injury by attenuating oxidative stress and apoptosis
- in-vivo, Nor, NA - in-vitro, Nor, NRK52E
*antiOx↑, *RenoP↑, *MDA↓, *SOD↑,
3283- ALA,    Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells
- in-vitro, Nor, NA
*TNF-α↓, *NF-kB↓, *antiOx↑, *IronCh↑, *GSSG↓, *VCAM-1↓, *E-sel↓, *ICAM-1↓, *MCP1↓, *NF-kB↓, IKKα↓,
1999- Api,  doxoR,    Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation
- in-vitro, Nor, NRK52E - in-vitro, Nor, MPC5 - in-vitro, BC, 4T1 - in-vivo, NA, NA
neuroP↑, ChemoSen∅, RenoP↑, selectivity↑, chemoP↑, ROS↑, *ROS∅, *antiOx↑, *toxicity↓,
4818- ASTX,  MEL,    Effect of astaxanthin and melatonin on cell viability and DNA damage in human breast cancer cell lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, T47D - in-vitro, Nor, MCF10
TumCD↑, DNAdam↑, *antiOx↑, *AntiTum↑, Inflam↓, tumCV↓, Bcl-2↓, Apoptosis↓, selectivity↑, eff↑, Dose↓,
4810- ASTX,    Effects of Astaxanthin on the Proliferation and Migration of Breast Cancer Cells In Vitro
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCP↓, TumCMig↓, selectivity↑, *BDNF↑, *ROS↓, *TNF-α↓, *IL6↓, *IFN-γ↓, *NF-kB↓, BAX⇅, Bcl-2↓, *antiOx↑, radioP↑, ChemoSen↑,
5417- ASTX,    Comparative Pharmacokinetic Study of Standard Astaxanthin and its Micellar Formulation in Healthy Male Volunteers
- Study, Nor, NA
*antiOx↑, *BioAv↓, *Dose↝, *BioAv↑,
5419- ASTX,    Astaxanthin and other Nutrients from Haematococcus pluvialis—Multifunctional Applications
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↓, AntiCan↑, *lipid-P↓, TumCP↓, Apoptosis↑, TumCCA↑, *SOD↑, *PGE2↓, *NO↓, *IL8↓, *IFN-γ↓, *cardioP↑, *NF-kB↓, *TNF-α↓, *BioAv↑,
5422- ASTX,    Improved intestinal absorption and oral bioavailability of astaxanthin using poly (ethylene glycol)-graft-chitosan nanoparticles: preparation, in vitro evaluation, and pharmacokinetics in rats
- in-vivo, Nor, NA
*antiOx↑, *AntiDiabetic↑, *toxicity∅, *BioAv↓, *BioAv↑,
5423- ASTX,    Pharmacokinetic Profile of Astaxanthin Nanoemulsion Using HPLC (High-Performance Liquid Chromatography) With Oral Routes
- in-vivo, Nor, NA
*BioAv↓, *antiOx↑, *BioAv↑, *Half-Life↝,
5365- AV,    Aloe Vera Polysaccharides as Therapeutic Agents: Benefits Versus Side Effects in Biomedical Applications
- Review, Nor, NA - Review, IBD, NA - Review, Diabetic, NA
*Wound Healing↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *AntiCan↑, *Inflam↓, *NF-kB↓, *COX2↓, *5LO↓, *IL1β↓, *IL6↓, *TNF-α↓, *IL10↑, *other↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *DNAdam↓, *GutMicro↑, *ZO-1↑, AntiTum↑, Casp3↑, Casp9↑, angioG↓, MMPs↓, VEGF↓, NK cell↑,
1535- Ba,    Baicalein May Act as a Caloric Restriction Mimetic Candidate to Improve the Antioxidant Profile in a Natural Rodent Model of Aging
- in-vivo, Nor, NA
*antiOx↑, *ROS∅, *CRM↑,
1527- Ba,    Baicalein Alleviates Arsenic-induced Oxidative Stress through Activation of the Keap1/Nrf2 Signalling Pathway in Normal Human Liver Cells
- in-vitro, Nor, MIHA
*p‑NRF2↑, *ROS↓, *MDA↓, *antiOx↑,
2607- Ba,  SIL,    Baicalein Enhances the Oral Bioavailability and Hepatoprotective Effects of Silybin Through the Inhibition of Efflux Transporters BCRP and MRP2
- in-vivo, Nor, NA
*BioEnh↑, *hepatoP↑, *antiOx↑, *Inflam↓,
2613- Ba,    Hepatoprotective Effect of Baicalein Against Acetaminophen-Induced Acute Liver Injury in Mice
- in-vivo, Nor, NA
*hepatoP↑, *MDA↓, *SOD↑, *Catalase↑, *GSH↑, *MAPK↓, *p‑JAK2↓, *p‑STAT3↓, *ALAT↓, *AST↓, *ROS↓, *antiOx↑,
2758- BetA,    Betulinic Acid Attenuates Oxidative Stress in the Thymus Induced by Acute Exposure to T-2 Toxin via Regulation of the MAPK/Nrf2 Signaling Pathway
- in-vivo, Nor, NA
*ROS↓, *MDA↓, *SOD↑, *GSH↑, *p‑p38↓, *p‑JNK↓, *p‑ERK↓, *NRF2↑, *HO-1↑, *MAPK↓, *heparanase↑, *antiOx↑,
5557- betaCar,    The Effect of Beta-Carotene on Cognitive Function: A Systematic Review
- Review, Nor, NA
*antiOx↑, *cognitive↑, *Dose↝, *eff↑,
5482- BM,    Bacopa monnieri protects SH-SY5Y cells against tert-Butyl hydroperoxide-induced cell death via the ERK and PI3K pathways
- in-vitro, Nor, NA
*neuroP↑, *ERK↑, *Akt↑, *MAPK↑, *PI3K↑, *Inflam↓, antiOx↑,
3517- Bor,  Se,    The protective effects of selenium and boron on cyclophosphamide-induced hepatic oxidative stress, inflammation, and apoptosis in rats
- in-vivo, Nor, NA
*hepatoP↑, *ALAT↓, *AST↓, *ALP↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL10↑, *SOD↑, *Catalase↑, *MDA↓, *GSH↑, *GPx↑, *antiOx↑, *NRF2↑, *Keap1↓,
3510- Bor,    Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks
- in-vivo, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *Apoptosis↓, *NRF2↑, *HO-1↑, *MDA↓, *lipid-P↓, *GPx↓, *Catalase↑, *SOD↑, *ALAT↓, *AST↓, *ALP↓,
5711- Brut,    Citrus bergamia powder: Antioxidant, antimicrobial and anti-inflammatory properties
- in-vitro, Nor, HMEC
*antiOx↑, *Bacteria↓, *GutMicro↑,
5834- CAP,    Capsaicin and TRPV1: A Novel Therapeutic Approach to Mitigate Vascular Aging
- Study, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *TRPV1↑, *AMPK↑, *SIRT1↑, *NADPH↓, *ROS↓, *MAPK↓, *eNOS↑, *Wnt/(β-catenin)↓, RenoP↑,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
5766- CAPE,    A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model
- in-vivo, Nor, NA
*MDA↓, *NF-kB↓, *p65↓, *TNF-α↓, *cl‑Casp3↓, *GSR↑, *GSH↑, *NRF2↑, *HO-1↑, *Bax:Bcl2↓, *antiOx↑, *Inflam↓,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2↓, *Dose↝,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,
6022- CGA,    Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *BP↓, *Dose↝, *ROS↓, *Fas↓, *HMG-CoA↓, *GutMicro↑,
6008- CGA,    Risk Assessment of Chlorogenic and Isochlorogenic Acids in Coffee By-Products
- Review, Nor, NA
*toxicity↓, *antiOx↑, *Bacteria↓, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *cardioP↑, *BP↓, *other↓, eff↓,
6010- CGA,    The Biological Activity Mechanism of Chlorogenic Acid and Its Applications in Food Industry: A Review
- Review, Nor, NA
*antiOx↑, *hepatoP↑, *RenoP↑, AntiTum↑, *glucose↝, *Inflam↓, *neuroP↑, *ROS↓, *Keap1↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *MDA↓, *p‑ERK↑, *GRP78/BiP↑, *CHOP↑, *GRP94↑, *Casp3↓, *Casp9↓, *HGF/c-Met↑, *TNF-α↓, *TLR4↓, *MAPK↓, *IL1β↓, *iNOS↓, TCA↓, Glycolysis↓, Bcl-2↓, BAX↑, MAPK↑, JNK↑, CSCs↓, Nanog↓, SOX2↓, CD44↓, OCT4↓, P53↑, P21↑, *SOD1↑, *AGEs↓, *GLUT2↑, *HDL↑, *Fas↓, *HMG-CoA↓, *NF-kB↓, *HO-1↓, *COX2↓, *TLR4↓, *BioAv↑, *BioAv↝, TumCP↓, TumCMig↓, TumCI↓,
6011- CGA,    Chlorogenic Acid’s Role in Metabolic Health: Mechanisms and Therapeutic Potential
- Review, Nor, NA
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,
6081- CHL,    Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review
- Review, Nor, NA
*antiOx↑, *toxicity↓, *BioAv↓, *BioAv↑, *neuroP↑, *Obesity↓, *AntiCan↑, *TumCP↓, *PhotoS↑, *neuroP↑,
6084- CHOC,    Cocoa Polyphenols and Their Potential Benefits for Human Health
- Review, Nor, NA - Review, Stroke, NA - Review, IBD, NA
*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2↓, *Obesity↓, *cognitive↑,
3700- Chol,    Eggs and Health Special Issue
- Review, Nor, NA
*other↑, *other↑, *Inflam↓, *ROS↓, *antiOx↑, *Iron↑, *cardioP∅,
2807- CHr,    Evidence-based mechanistic role of chrysin towards protection of cardiac hypertrophy and fibrosis in rats
- in-vivo, Nor, NA
*antiOx↑, Inflam↓, *cardioP↑, *GSH↑, *SOD↑, *Catalase↑, *GAPDH↑, *BAX↓, *Bcl-2↑, *PARP↓, *Cyt‑c↓, *Casp3↓, *NOX4↓, *NRF2↑, *HO-1↑, *HSP70/HSPA5↑,
2466- CUR,    Regulatory Effects of Curcumin on Platelets: An Update and Future Directions
- Review, Nor, NA
*AntiAg↑, *antiOx↑, *Inflam↓, *12LOX↑, COX1↓, COX2↓, MMP9↓, NF-kB↓,
3221- EGCG,    EGCG upregulates phase-2 detoxifying and antioxidant enzymes via the Nrf2 signaling pathway in human breast epithelial cells
- in-vitro, Nor, MCF10
*antiOx↑, *GSTA1↑, *NRF2↑,
3210- EGCG,    Protective effect of epigallocatechin-3-gallate (EGCG) via Nrf2 pathway against oxalate-induced epithelial mesenchymal transition (EMT) of renal tubular cells
- in-vitro, Nor, NA
*ROS↓, *NRF2↑, *Catalase↑, *antiOx↑,
1974- EGCG,    Protective Effect of Epigallocatechin-3-Gallate in Hydrogen Peroxide-Induced Oxidative Damage in Chicken Lymphocytes
- in-vitro, Nor, NA
*ROS↓, *NO↓, *MMP↑, *i-Ca+2↓, *HO-1↑, *Catalase↑, *NRF2↑, *Trx1↑, *antiOx↑, *SOD↑, *Apoptosis↓,
2861- FIS,    The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
- Review, Nor, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
5392- FIS,  AsP,    Fisetin topical delivery via ascorbyl palmitate/hyaluronan-enhanced limosomes: a novel paradigm for preventing UVB-induced skin photoaging
- in-vivo, Nor, NA
eff↑, *antiOx↑, *MMP9↓, *TNF-α↓, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAge↑, *Inflam↓, *JNK↓,
2464- GI,    The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review
- Review, Nor, NA
*Inflam↓, *antiOx↑, *LDL↓, *AntiAg↑, *AntiAg∅,
1638- HCAs,    Anticancer potential of hydroxycinnamic acids: mechanisms, bioavailability, and therapeutic applications
- Review, Nor, NA
*BioAv↓, Inflam↓, COX2↓, TumCCA↑, ChemoSen↑, RadioS↑, selectivity↑, ROS↑, DNAdam↑, antiOx↑, SOD↑, Catalase↑, GPx↑, GSH↑, NRF2↑, NF-kB↓, Cyc↓, CDK1↑, P21↑, p27↑, P53↑, VEGF↓, MAPK↓,
2071- HNK,    Identification of senescence rejuvenation mechanism of Magnolia officinalis extract including honokiol as a core ingredient
- Review, Nor, HaCaT
*ROS↓, *antiOx↑, *AntiAge↑, *MMP↑, *ECAR↓, *Glycolysis↓, *PAR-2↓, *CXCL12↑, *BMAL1↑, *mt-ROS↓, *OXPHOS↓,
2873- HNK,    Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2
- in-vitro, Nor, PC12
*neuroP↑, *GSH↑, *HO-1↑, *NADPH↑, *Trx1↑, *TrxR1↑, *NRF2↑, *ROS↓, *antiOx↑, *BBB↑, Dose↓,
2867- HNK,    Honokiol ameliorates oxidative stress-induced DNA damage and apoptosis of c2c12 myoblasts by ROS generation and mitochondrial pathway
- in-vitro, Nor, C2C12
*antiOx↑, *ROS↓, *Bcl-2↑, *BAX↓, Casp9∅, Casp3∅, cl‑PARP∅, Cyt‑c?,
5119- JG,    Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice
- in-vivo, Nor, NA
*antiOx↑, *OS↑, *IL6↓, *IL12↓, *IL23↓, *TNF-α↓, *Inflam↓, *NF-kB↓, *NFE2L2↓, *ROS↓,
1791- LEC,    Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention
- Review, Nor, NA
*BioEnh↑, *antiOx↑, *BioEnh↑, *LDL↓, *HDL∅, *Obesity↓, eff↑, GutMicro↝,

Showing Research Papers: 1 to 50 of 106
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 106

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   Catalase↑, 1,   CYP1A1↓, 1,   GPx↑, 1,   GSH↑, 1,   GSTs↑, 1,   HO-1↑, 1,   NADH↓, 1,   NRF2↑, 2,   ROS↑, 4,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 2,   MPT↑, 1,  

Core Metabolism/Glycolysis ⓘ

Glycolysis↓, 1,   SIRT1↓, 1,   TCA↓, 1,  

Cell Death ⓘ

Apoptosis↓, 1,   Apoptosis↑, 2,   BAX↑, 1,   BAX⇅, 1,   Bcl-2↓, 3,   Casp↑, 1,   Casp3↑, 1,   Casp3∅, 1,   Casp9↑, 1,   Casp9∅, 1,   Cyt‑c↑, 1,   Cyt‑c?, 1,   JNK↑, 1,   MAPK↓, 1,   MAPK↑, 1,   p27↑, 1,   p38↑, 1,   TumCD↓, 1,   TumCD↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   P53↑, 2,   cl‑PARP∅, 1,  

Cell Cycle & Senescence ⓘ

CDK1↑, 1,   Cyc↓, 1,   P21↑, 2,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State ⓘ

CD44↓, 1,   CSCs↓, 1,   Nanog↓, 1,   OCT4↓, 1,   SOX2↓, 1,   TOP1↓, 1,   TOP2↓, 1,   TumCG↓, 1,  

Migration ⓘ

MMP9↓, 1,   MMPs↓, 1,   TRIB3↑, 1,   TumCI↓, 1,   TumCMig↓, 3,   TumCP↓, 3,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   VEGF↓, 2,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 1,   COX2↓, 3,   IKKα↓, 1,   IL1β↓, 1,   Inflam↓, 3,   NF-kB↓, 3,   NK cell↑, 1,   PGE2↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↝, 3,   ChemoSen↑, 2,   ChemoSen∅, 1,   Dose↓, 2,   eff↓, 1,   eff↑, 3,   RadioS↑, 1,   selectivity↑, 5,  

Clinical Biomarkers ⓘ

GutMicro↝, 1,   TRIB3↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiTum↑, 2,   chemoP↑, 1,   cognitive↑, 1,   neuroP↑, 1,   Obesity↓, 1,   radioP↑, 1,   RenoP↑, 2,  
Total Targets: 86

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 48,   Catalase↑, 13,   GPx↓, 1,   GPx↑, 4,   GSH↑, 10,   GSR↑, 2,   GSSG↓, 1,   GSTA1↑, 1,   GSTs↑, 1,   HDL↑, 1,   HDL∅, 1,   HO-1↓, 1,   HO-1↑, 6,   Iron↑, 1,   Keap1↓, 2,   lipid-P↓, 6,   MDA↓, 11,   MPO↓, 1,   NFE2L2↓, 1,   NOX4↓, 1,   Nrf1↑, 1,   NRF2↑, 12,   p‑NRF2↑, 1,   OXPHOS↓, 1,   ROS↓, 21,   ROS∅, 2,   mt-ROS↓, 1,   SOD↑, 14,   SOD1↑, 1,   Trx1↑, 2,   TrxR1↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↑, 1,   MMP↑, 2,  

Core Metabolism/Glycolysis ⓘ

12LOX↓, 1,   12LOX↑, 1,   ALAT↓, 4,   AMPK↑, 1,   BMAL1↑, 1,   CRM↑, 1,   ECAR↓, 1,   GAPDH↑, 1,   glucose↝, 1,   GLUT2↑, 1,   Glycolysis↓, 1,   HMG-CoA↓, 2,   LDL↓, 2,   NADPH↓, 1,   NADPH↑, 1,   SIRT1↑, 2,  

Cell Death ⓘ

Akt↑, 1,   Apoptosis↓, 2,   BAX↓, 2,   Bax:Bcl2↓, 1,   Bcl-2↑, 2,   Casp3↓, 2,   cl‑Casp3↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   Fas↓, 2,   HGF/c-Met↑, 1,   iNOS↓, 1,   JNK↓, 1,   p‑JNK↓, 1,   MAPK↓, 4,   MAPK↑, 1,   p‑p38↓, 1,   TRPV1↑, 2,  

Kinase & Signal Transduction ⓘ

TRPV3↑, 1,  

Transcription & Epigenetics ⓘ

other↓, 3,   other↑, 3,   other↝, 1,   PhotoS↑, 1,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   GRP78/BiP↑, 1,   GRP94↑, 1,   HSP70/HSPA5↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,   PARP↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↑, 1,   p‑ERK↓, 1,   p‑ERK↑, 1,   PI3K↑, 1,   p‑STAT3↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration ⓘ

5LO↓, 3,   AntiAg↑, 6,   AntiAg∅, 1,   Ca+2↑, 2,   i-Ca+2↓, 1,   CXCL12↑, 1,   E-sel↓, 1,   heparanase↑, 1,   MMP9↓, 1,   PKCδ↑, 1,   TumCP↓, 1,   VCAM-1↓, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature ⓘ

eNOS↑, 1,   NO↓, 4,   NO↑, 1,   VEGF↓, 2,  

Barriers & Transport ⓘ

BBB↓, 1,   BBB↑, 2,   GastroP↑, 1,   OCLN↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 5,   CRP↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 2,   IL10↑, 2,   IL12↓, 1,   IL1β↓, 3,   IL23↓, 1,   IL6↓, 4,   IL6↑, 1,   IL8↓, 1,   Imm↑, 2,   Inflam↓, 21,   p‑JAK2↓, 1,   MCP1↓, 1,   NF-kB↓, 13,   p65↓, 1,   PAR-2↓, 1,   PGE2↓, 1,   TLR4↓, 2,   TNF-α↓, 10,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,   BChE↓, 1,   BDNF↑, 2,  

Protein Aggregation ⓘ

AGEs↓, 1,   Aβ↓, 2,   NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 8,   BioAv↑, 8,   BioAv⇅, 1,   BioAv↝, 2,   BioEnh↑, 3,   Dose↝, 6,   eff↑, 4,   Half-Life↓, 1,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 4,   ALP↓, 2,   AST↓, 4,   BP↓, 3,   CRP↓, 1,   GutMicro↑, 5,   IL6↓, 4,   IL6↑, 1,  

Functional Outcomes ⓘ

AntiAge↑, 2,   AntiCan↑, 4,   AntiDiabetic↓, 1,   AntiDiabetic↑, 6,   AntiTum↑, 1,   cardioP↑, 9,   cardioP∅, 1,   chemoPv↑, 2,   cognitive↑, 3,   hepatoP↑, 9,   neuroP↑, 11,   Obesity↓, 6,   OS↑, 2,   Pain↓, 2,   RenoP↑, 5,   Risk↓, 1,   toxicity↓, 5,   toxicity↑, 1,   toxicity↝, 1,   toxicity∅, 1,   Wound Healing↑, 2,  

Infection & Microbiome ⓘ

Bacteria↓, 4,   Diar↓, 1,  
Total Targets: 173

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
8 Thymoquinone
6 Resveratrol
6 Astaxanthin
6 Lycopene
6 Propolis -bee glue
5 Silymarin (Milk Thistle) silibinin
4 Baicalein
4 Chlorogenic acid
4 EGCG (Epigallocatechin Gallate)
4 Honokiol
4 Selenium NanoParticles
3 Silver-NanoParticles
3 Rosmarinic acid
3 Luteolin
3 Magnetic Fields
3 Quercetin
3 Shikonin
3 Vitamin C (Ascorbic Acid)
2 doxorubicin
2 Boron
2 Selenium
2 Capsaicin
2 Carvacrol
2 Curcumin
2 Fisetin
2 Magnolol
2 Phenylbutyrate
2 Radiotherapy/Radiation
1 Ajoene (compound of Garlic)
1 Allicin (mainly Garlic)
1 Alpha-Lipoic-Acid
1 Apigenin (mainly Parsley)
1 Melatonin
1 Aloe anthraquinones
1 Betulinic acid
1 beta-carotene(VitA)
1 Bacopa monnieri
1 Bruteridin(bergamot juice)
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Chlorophyllin
1 Chocolate
1 Choline
1 Chrysin
1 Ascorbyl Palmitate
1 Ginger/6-Shogaol/Gingerol
1 Hydroxycinnamic-acid
1 Juglone
1 Lecithin
1 nicotinamide adenine dinucleotide
1 Caffeic acid
1 chitosan
1 Aflavin-3,3′-digallate
1 Cisplatin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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