adiP Cancer Research Results

adiP, adiponectin: Click to Expand ⟱
Source:
Type:
Adiponectin is an adipokine with anti-inflammatory and insulin-sensitizing properties, and its effects on tumor biology are thought to be mediated through influences on cell proliferation, apoptosis, and metabolic regulation.

Adiponectin is a key metabolic hormone whose levels have been associated with cancer risk and prognosis across multiple tumor types. Generally, lower adiponectin levels tend to correlate with more aggressive tumor phenotypes and poorer outcomes, while higher levels may offer a degree of protection.


Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy

Scientific Papers found: Click to Expand⟱
2269- dietMet,    Mechanisms of Increased In Vivo Insulin Sensitivity by Dietary Methionine Restriction in Mice
- in-vivo, Nor, NA
*adiP↑, *FGF↑, *Insulin↓, *glucose↓, *Akt↑, *GSH↓, *PTEN↓, *FGF21↑, *PIP3↑,
2265- dietMet,    Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase
- in-vivo, Nor, NA
*SCD1↓, *Weight↓, *Insulin↓, *IGF-1↓, *adiP↑, *eff↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

GSH↓, 1,  

Mitochondria & Bioenergetics

Insulin↓, 2,  

Core Metabolism/Glycolysis

adiP↑, 2,   FGF21↑, 1,   glucose↓, 1,   PIP3↑, 1,   SCD1↓, 1,  

Cell Death

Akt↑, 1,  

Proliferation, Differentiation & Cell State

FGF↑, 1,   IGF-1↓, 1,   PTEN↓, 1,  

Drug Metabolism & Resistance

eff↓, 1,  

Functional Outcomes

Weight↓, 1,  
Total Targets: 13

Scientific Paper Hit Count for: adiP, adiponectin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:1191  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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