Jun Cancer Research Results

Jun, Jun: Click to Expand ⟱
Source:
Type:
The JUN proto-oncogene is a gene that encodes a protein called c-Jun, which is a component of the AP-1 (Activator Protein 1) transcription factor complex.
Jun is a key component of the AP-1 (Activator Protein 1) transcription factor complex, which plays a significant role in regulating gene expression in response to various stimuli, including growth factors, stress, and cytokines. The Jun family includes several proteins, such as c-Jun, JunB, and JunD, which can have distinct roles in cancer biology.

In many cancers, Jun, particularly c-Jun, is activated and promotes cell proliferation, survival, and invasion. This activation is typically associated with poor prognosis and aggressive tumor behavior.
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
232- AL,    A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans
- Human, Nor, NA
*AhR↑, *ARNT↑, *Hif1a↑, *Jun↑, *NFAT↑, *NFAM1↑, *REL↑, *OSM↑, *NFAT↑, *CXCc↑, *IL2↑, *IL6↑, *LIF↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Cell Death ⓘ

AhR↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

Jun↑, 1,  

Migration ⓘ

NFAM1↑, 1,   NFAT↑, 2,  

Angiogenesis & Vasculature ⓘ

Hif1a↑, 1,   REL↑, 1,  

Immune & Inflammatory Signaling ⓘ

CXCc↑, 1,   IL2↑, 1,   IL6↑, 1,   LIF↑, 1,   OSM↑, 1,  

Hormonal & Nuclear Receptors ⓘ

ARNT↑, 1,  

Clinical Biomarkers ⓘ

IL6↑, 1,  
Total Targets: 13

Scientific Paper Hit Count for: Jun, Jun
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:169  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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