| Antiallergic Activity - Suppression of Allergic Responses
Type: Therapeutic effect / immune phenotype / functional outcome
Function: Antiallergic activity refers to suppression of allergic sensitization, mast-cell or basophil activation, IgE-mediated signaling, eosinophilic inflammation, histamine and leukotriene release, airway inflammation, or other manifestations of hypersensitivity.
Asthma: ↓ Allergic response is favorable. Increased antiallergic activity corresponds to reduced IgE/FcεRI signaling, mast-cell degranulation, eosinophil recruitment, type-2 cytokine signaling, mucus production, bronchoconstriction, and airway hyperresponsiveness.
Favorable Direction: ↑ Antiallergic activity = beneficial.
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