OS Cancer Research Results

OS, overall survival: Click to Expand ⟱
Source:
Type:
Overall survival
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
2326- 2DG,    Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury via Suppressing Nuclear Pyruvate Kinase M2–Signal Transducer and Activator of Transcription 3 Pathway
- in-vivo, Nor, NA
PKM2↓, Inflam↓, TNF-α↓, IL6↓, OS↑,
4402- AgNPs,    Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors
- in-vitro, BC, BT549 - in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCD↑, selectivity↑, *toxicity↝, Dose↝, OS↑,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2↓, *Dose↝,
2393- Cela,    Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect
- in-vivo, Sepsis, NA - in-vitro, Nor, RAW264.7
OS↑, PKM2↓, Glycolysis↓, Warburg↓, Inflam↓, HMGB1↓, ALAT↓, AST↓, TNF-α↓, IL1β↓, IL6↓,
6030- CGA,    Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway
- vitro+vivo, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-453 - in-vitro, Nor, MCF10
NF-kB↓, AntiTum↑, tumCV↓, TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, EMT↓, TumCG↓, OS↑, TumMeta↓, CD4+↑, CD8+↑, Imm↑,
6091- CHOC,    Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative
- Study, Nor, NA
*Risk↓, *cardioP↑, *OS↑,
5783- CUR,  EGCG,    The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice
- in-vivo, Nor, NA
*OS↑,
1894- dietMet,    Long term methionine restriction: Influence on gut microbiome and metabolic characteristics
- in-vivo, Nor, NA
*GutMicro↓, *OS↑, Weight↓, BG↓,
2272- dietMet,    Methionine restriction - Association with redox homeostasis and implications on aging and diseases
- Review, Nor, NA
*OS↑, *mt-ROS↓, *H2S↑, *FGF21↑, *cognitive↑, *GutMicro↑, *IGF-1↓, *mTOR↓, *GSH↑, *SOD↑, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *GLUT4↑, *Glycolysis↑, *HK2↑, *PFK↑, *PKM2↑, *GlucoseCon↑, *ATF4↑, *PPARα↑, GSH↓, GSTs↑, ROS↑, *neuroP↑,
5784- EGCG,    Dietary Epicatechin Promotes Survival of Obese Diabetic Mice and Drosophila melanogaster
- in-vivo, Nor, NA
*OS↑, *Inflam↓, *LDL↓, *AntiAge↑, *GSH↑, *SOD↑, *AMPKα↑, *Weight∅,
3152- H2,  VitC,  Rad,    Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
- in-vitro, Nor, HUVECs - in-vivo, NA, NA
AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, eff↑,
1415- HCA,    Hydroxycitrate delays early mortality in mice and promotes muscle regeneration while inducing a rich hepatic energetic status
- in-vivo, Nor, NA
*OS↑, *toxicity↓, *AST∅, *ALAT∅, *Strength↑, *memory∅, *other↑, *other↑, *other↑,
5119- JG,    Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice
- in-vivo, Nor, NA
*antiOx↑, *OS↑, *IL6↓, *IL12↓, *IL23↓, *TNF-α↓, *Inflam↓, *NF-kB↓, *NFE2L2↓, *ROS↓,
5534- MF,    Targeted Osmotic Lysis of Highly Invasive Breast Carcinomas Using Pulsed Magnetic Field Stimulation of Voltage-Gated Sodium Channels and Pharmacological Blockade of Sodium Pumps
- vitro+vivo, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumVol↓, VGSC↑, OS↑, selectivity↑, eff↑,
3499- MFrot,  MF,    Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans
- in-vitro, Nor, HUVECs
*AntiAge↑, *AMPK↑, *mPGES-1↓, *Ca+2↑, *ER Stress↑, *OS↑, *ROS↓,
2258- MFrot,  MF,    EXTH-68. ONCOMAGNETIC TREATMENT SELECTIVELY KILLS GLIOMA CANCER CELLS BY INDUCING OXIDATIVE STRESS AND DNA DAMAGE
- in-vitro, GBM, GBM - in-vitro, Nor, SVGp12
TumVol↓, OS↑, γH2AX↑, DNAdam↑, selectivity↑, ROS↑, TumCD↑, eff↑, eff↓,
5245- MFrot,  Rad,    The hemoprotective effects of a rotary magnetic field in mice exposed to γ irradiation
- in-vivo, Nor, NA
*OS↑, *radioP↑,
5787- NAD,    Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
- in-vitro, Nor, NA
*CRM↑, *OS↑,
2933- NAD,    Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns
- Review, Nor, NA - NA, AD, NA - NA, Diabetic, NA - NA, Stroke, NA - NA, LiverDam, NA - NA, Park, NA
*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,
2935- NAD,    Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner
- in-vitro, Nor, NA
*GutMicro↑, *OS↑,
2131- TQ,    Therapeutic impact of thymoquninone to alleviate ischemic brain injury via Nrf2/HO-1 pathway
- in-vitro, Stroke, NA - in-vivo, Nor, NA
*eff↑, *OS↑, *Inflam↓, *ROS↓, *NRF2↑, *HO-1↑,
3420- TQ,    Thymoquinone alleviates the accumulation of ROS and pyroptosis and promotes perforator skin flap survival through SIRT1/NF-κB pathway
- in-vitro, Nor, HUVECs - in-vitro, NA, NA
*NF-kB↓, *NLRP3↓, *angioG↑, *MMP9↑, *VEGF↑, *OS↑, *Pyro?, *ROS↓, *Apoptosis↓, *SIRT1↑, *SOD1↑, *HO-1↑, *eNOS↑, *ASC?, *Casp1↓, *IL1β↓, *IL18↓,
3147- VitC,    Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo−/− mice
- in-vivo, Nor, NA
*OS↑, *ER Stress↓, *GRP78/BiP↓,

Showing Research Papers: 1 to 23 of 23

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 23

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

GSH↓, 1,   GSTs↑, 1,   ROS↑, 3,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   Glycolysis↓, 1,   PKM2↓, 2,   Warburg↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   TumCD↑, 2,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   γH2AX↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   TumCG↓, 1,   VGSC↑, 1,  

Migration ⓘ

TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,   TumMeta↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↑, 1,   HMGB1↓, 1,   IL1β↓, 1,   IL6↓, 2,   Imm↑, 1,   Inflam↓, 2,   NF-kB↓, 1,   TNF-α↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↝, 1,   Dose↑, 1,   Dose↝, 2,   eff↓, 1,   eff↑, 3,   selectivity↑, 3,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AST↓, 1,   BG↓, 1,   IL6↓, 2,  

Functional Outcomes ⓘ

AntiTum↑, 2,   OS↑, 7,   QoL↑, 1,   radioP↑, 1,   TumVol↓, 3,   Weight↓, 1,  

Infection & Microbiome ⓘ

CD8+↑, 1,  
Total Targets: 45

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 2,   GSR↑, 1,   HO-1↑, 3,   lipid-P↓, 1,   MDA↓, 2,   NFE2L2↓, 1,   NQO1↑, 1,   NRF2↑, 2,   ROS↓, 5,   mt-ROS↓, 1,   SOD↑, 3,   SOD1↑, 1,  

Mitochondria & Bioenergetics ⓘ

mtDam↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT∅, 1,   AMPK↑, 1,   CRM↑, 1,   FGF21↑, 1,   GlucoseCon↑, 1,   Glycolysis↑, 1,   H2S↑, 1,   HK2↑, 1,   LDL↓, 1,   PFK↑, 1,   PKM2↑, 1,   PPARα↑, 1,   SIRT1↑, 2,  

Cell Death ⓘ

Apoptosis↓, 1,   Casp1↓, 1,   Pyro?, 1,  

Kinase & Signal Transduction ⓘ

AMPKα↑, 1,  

Transcription & Epigenetics ⓘ

other↑, 4,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   ER Stress↑, 1,   GRP78/BiP↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1↓, 1,   mTOR↓, 1,  

Migration ⓘ

AntiAg↑, 1,   Ca+2↑, 1,   MMP9↑, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 1,   ATF4↑, 1,   eNOS↑, 1,   VEGF↑, 1,  

Barriers & Transport ⓘ

GLUT4↑, 1,  

Immune & Inflammatory Signaling ⓘ

ASC?, 1,   COX2↓, 1,   IL12↓, 1,   IL18↓, 1,   IL1β↓, 1,   IL23↓, 1,   IL6↓, 1,   Inflam↓, 4,   mPGES-1↓, 1,   NF-kB↓, 2,   TNF-α↓, 1,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 2,   BioAv↝, 1,   Dose↝, 2,   eff↑, 4,  

Clinical Biomarkers ⓘ

ALAT∅, 1,   AST∅, 1,   BG↓, 1,   creat↓, 1,   GutMicro↓, 1,   GutMicro↑, 2,   IL6↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 2,   AntiDiabetic↑, 1,   cardioP↑, 3,   cognitive↑, 2,   hepatoP↑, 2,   memory∅, 1,   neuroP↑, 2,   Obesity↓, 1,   OS↑, 16,   Pain↓, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 1,   Strength↑, 1,   toxicity↓, 2,   toxicity↝, 1,   Weight∅, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 90

Scientific Paper Hit Count for: OS, overall survival
3 Magnetic Fields
3 Magnetic Field Rotating
3 nicotinamide adenine dinucleotide
2 EGCG (Epigallocatechin Gallate)
2 diet Methionine-Restricted Diet
2 Vitamin C (Ascorbic Acid)
2 Radiotherapy/Radiation
2 Thymoquinone
1 2-DeoxyGlucose
1 Silver-NanoParticles
1 Carvacrol
1 Celastrol
1 Chlorogenic acid
1 Chocolate
1 Curcumin
1 Hydrogen Gas
1 HydroxyCitric Acid
1 Juglone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:229  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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