IL2 Cancer Research Results

IL2, Interleukin-2: Click to Expand ⟱
Source:
Type:
The cytokine interleukin-2 (IL-2) can stimulate both effector immune cells and regulatory T (Treg) cells.

IL-2 is often expressed in various cancers, including melanoma, renal cell carcinoma, and certain hematological malignancies. Its expression can vary depending on the tumor type and the immune context.
Tumor-infiltrating lymphocytes (TILs), particularly activated T cells, are significant sources of IL-2 in the tumor microenvironment.

IL-2 is primarily known for its role in promoting anti-tumor immunity. It stimulates the proliferation and activation of T cells, enhancing their ability to recognize and kill tumor cells.
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
232- AL,    A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans
- Human, Nor, NA
*AhR↑, *ARNT↑, *Hif1a↑, *Jun↑, *NFAT↑, *NFAM1↑, *REL↑, *OSM↑, *NFAT↑, *CXCc↑, *IL2↑, *IL6↑, *LIF↑,
3110- VitC,    Vitamin C Attenuates Oxidative Stress, Inflammation, and Apoptosis Induced by Acute Hypoxia through the Nrf2/Keap1 Signaling Pathway in Gibel Carp (Carassius gibelio)
- in-vivo, Nor, NA
*IL2↑, *IL6↑, *IL12↑, *NRF2↑, *Catalase↑, *SOD↑, *GPx↑, *GRP78/BiP↓, *ER Stress↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 1,   GPx↑, 1,   NRF2↑, 1,   SOD↑, 1,  

Cell Death ⓘ

AhR↑, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   GRP78/BiP↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

Jun↑, 1,  

Migration ⓘ

NFAM1↑, 1,   NFAT↑, 2,  

Angiogenesis & Vasculature ⓘ

Hif1a↑, 1,   REL↑, 1,  

Immune & Inflammatory Signaling ⓘ

CXCc↑, 1,   IL12↑, 1,   IL2↑, 2,   IL6↑, 2,   LIF↑, 1,   OSM↑, 1,  

Hormonal & Nuclear Receptors ⓘ

ARNT↑, 1,  

Clinical Biomarkers ⓘ

IL6↑, 2,  
Total Targets: 20

Scientific Paper Hit Count for: IL2, Interleukin-2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:366  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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