Cartilage Cancer Research Results

Cartilage, Cartilage: Click to Expand ⟱
Source:
Type:
Cartilage is a flexible connective tissue found in multiple areas of the body, including joints, the ear and nose, and intervertebral discs.
The most common type of arthritis, osteoarthritis involves wear-and-tear damage to a joint's cartilage.
Chondrosarcoma is a rare type of bone cancer that develops in cartilage cells.
Cartilage Degradation: Cancer can lead to the degradation of cartilage, particularly in joint-related cancers. This degradation can result in pain and loss of function, impacting the patient's quality of life.
Biomarkers: Specific proteins and genes associated with cartilage metabolism (e.g., collagen types, aggrecan, and matrix metalloproteinases) can serve as biomarkers for cancer diagnosis and prognosis. Their expression levels may indicate the presence of malignancy or the aggressiveness of a tumor.


Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy

Scientific Papers found: Click to Expand⟱
5336- TFdiG,    Theaflavin-3,3′-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways
- in-vivo, Nor, NA
*IL6↓, *TNF-α↓, *iNOS↓, *PGE1↓, *ROS↓, *Inflam↓, *PI3K↓, *Akt↓, *NF-kB↓, *MAPK↓, *Cartilage↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

ROS↓, 1,  

Cell Death

Akt↓, 1,   iNOS↓, 1,   MAPK↓, 1,  

Proliferation, Differentiation & Cell State

PI3K↓, 1,  

Migration

Cartilage↑, 1,  

Immune & Inflammatory Signaling

IL6↓, 1,   Inflam↓, 1,   NF-kB↓, 1,   PGE1↓, 1,   TNF-α↓, 1,  

Clinical Biomarkers

IL6↓, 1,  
Total Targets: 12

Scientific Paper Hit Count for: Cartilage, Cartilage
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:539  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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