eff Cancer Research Results
eff, efficacy: Click to Expand ⟱
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| Type: |
Power to enhance an anti cancer effect
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Nor, Normal Healthy: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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in-vitro, |
Nor, |
RAW264.7 |
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*Wound Healing↑, *eff↝, *toxicity↝,
*Half-Life↝, *toxicity↓, *Dose↑, *other↝, *eff↝, *BioAv↓,
*DNAdam↑, *toxicity↝, eff↝,
Inflam↓, IL6↓, MCP1↓, COX2↓, PGE2↓, MMP2↓, MMP9↓, DNAdam↑, eff↝, Telomerase↓, Bcl-2↓, AMPK↑, ROS↑, MMP↓, ATP↓, p‑mTORC1↓, p‑S6K↓, ERK↓, PI3K↓, PTEN↑, Akt↓, Raf↓, MEK↓, Dose↓, Dose↑, selectivity↑, TumCCA↑, eff↑, EGFR↓, Glycolysis↓, Dose?, p27↑, CDK2↓, CDK4↓, cycD1/CCND1↓, cycE/CCNE↓, Bax:Bcl2↑, Casp3↑, Casp9↑, VEGFR2↓, ChemoSen↑, eff↑, eff↑, PGE2↓, JAK2↓, STAT3↓, CXCR4↓, CCR7↓, uPA↓, CSCs↓, EMT↓, Diff↓, CD133↓, Nestin↓, n-MYC↓, NOTCH↓, SOX2↓, Hif1a↓, VEGF↓, RadioS↑,
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in-vitro, |
Nor, |
NA |
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in-vivo, |
Nor, |
NA |
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*BioAv↑, *eff↝, BioEnh↑,
other↑, eff↝, eff↝, other↝, other↝, other↝, other↝, other↝,
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in-vitro, |
Nor, |
C3H10T1/2 |
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*Ca+2↑, *Diff↑, *BMD↑, *Wnt↑, *β-catenin/ZEB1↑, *eff↝,
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in-vitro, |
BC, |
MDA-MB-231 |
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in-vitro, |
BC, |
MCF-7 |
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in-vitro, |
Nor, |
MCF10 |
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TumCP↓, MMP↓, ROS↑, eff↝, selectivity↑,
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in-vitro, |
BC, |
MCF-7 |
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in-vitro, |
BC, |
MDA-MB-231 |
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in-vivo, |
Nor, |
MCF10 |
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Ca+2↑, Apoptosis↑, eff↝, eff↑, selectivity↑, eff↝, eff↝,
*mt-OCR↑, *mt-ROS↑, *ECAR↑, *Dose↝, *Ca+2↑, *ATP↑, *other↑, *eff↓, *eff↝,
*NO↑, *5HT↓, *eff↝, *eff↝, *β-Endo↑, *other↓,
glut↓, NH3↓, eff↝,
*ROS↑, *GSTA1↓, eff↝, *toxicity↓, ROS↑, *Hif1a↓,
*eff↝, *LDH↓,
BioAv↝, Half-Life↝, BioAv↓, eff↝,
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in-vitro, |
Lung, |
A549 |
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in-vitro, |
Nor, |
BEAS-2B |
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chemoP↑, eff↝, ROS↑, MMP↓, Cyt‑c↑, TumCG↓, RadioS↝, other↝,
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in-vitro, |
Nor, |
GP-293 |
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in-vitro, |
Kidney, |
ACHN |
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selectivity↑, eff↝,
*Apoptosis∅, *LDH∅, *MDA∅, *SOD↓, eff↝,
TET1↑, eff↝,
eff↑, Dose↝, eff↝, eff↑, eff↑,
Showing Research Papers: 1 to 20 of 20
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 20
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 4,
Mitochondria & Bioenergetics ⓘ
ATP↓, 1, MEK↓, 1, MMP↓, 3, Raf↓, 1,
Core Metabolism/Glycolysis ⓘ
AMPK↑, 1, glut↓, 1, Glycolysis↓, 1, NH3↓, 1, p‑S6K↓, 1,
Cell Death ⓘ
Akt↓, 1, Apoptosis↑, 1, Bax:Bcl2↑, 1, Bcl-2↓, 1, Casp3↑, 1, Casp9↑, 1, Cyt‑c↑, 1, p27↑, 1, Telomerase↓, 1,
Transcription & Epigenetics ⓘ
other↑, 1, other↝, 6,
DNA Damage & Repair ⓘ
DNAdam↑, 1,
Cell Cycle & Senescence ⓘ
CDK2↓, 1, CDK4↓, 1, cycD1/CCND1↓, 1, cycE/CCNE↓, 1, TumCCA↑, 1,
Proliferation, Differentiation & Cell State ⓘ
CD133↓, 1, CSCs↓, 1, Diff↓, 1, EMT↓, 1, ERK↓, 1, p‑mTORC1↓, 1, n-MYC↓, 1, Nestin↓, 1, NOTCH↓, 1, PI3K↓, 1, PTEN↑, 1, SOX2↓, 1, STAT3↓, 1, TumCG↓, 1,
Migration ⓘ
Ca+2↑, 1, MMP2↓, 1, MMP9↓, 1, TET1↑, 1, TumCP↓, 1, uPA↓, 1,
Angiogenesis & Vasculature ⓘ
EGFR↓, 1, Hif1a↓, 1, VEGF↓, 1, VEGFR2↓, 1,
Immune & Inflammatory Signaling ⓘ
CCR7↓, 1, COX2↓, 1, CXCR4↓, 1, IL6↓, 1, Inflam↓, 1, JAK2↓, 1, MCP1↓, 1, PGE2↓, 2,
Drug Metabolism & Resistance ⓘ
BioAv↓, 1, BioAv↝, 1, BioEnh↑, 1, ChemoSen↑, 1, Dose?, 1, Dose↓, 1, Dose↑, 1, Dose↝, 1, eff↑, 7, eff↝, 16, Half-Life↝, 1, RadioS↑, 1, RadioS↝, 1, selectivity↑, 4,
Clinical Biomarkers ⓘ
EGFR↓, 1, IL6↓, 1,
Functional Outcomes ⓘ
chemoP↑, 1,
Total Targets: 76
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
GSTA1↓, 1, MDA∅, 1, ROS↑, 1, mt-ROS↑, 1, SOD↓, 1,
Mitochondria & Bioenergetics ⓘ
ATP↑, 1, mt-OCR↑, 1,
Core Metabolism/Glycolysis ⓘ
ECAR↑, 1, LDH↓, 1, LDH∅, 1,
Cell Death ⓘ
Apoptosis∅, 1,
Transcription & Epigenetics ⓘ
other↓, 1, other↑, 1, other↝, 1,
DNA Damage & Repair ⓘ
DNAdam↑, 1,
Proliferation, Differentiation & Cell State ⓘ
Diff↑, 1, Wnt↑, 1,
Migration ⓘ
Ca+2↑, 2, β-catenin/ZEB1↑, 1, β-Endo↑, 1,
Angiogenesis & Vasculature ⓘ
Hif1a↓, 1, NO↑, 1,
Synaptic & Neurotransmission ⓘ
5HT↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↓, 1, BioAv↑, 1, Dose↑, 1, Dose↝, 1, eff↓, 1, eff↝, 8, Half-Life↝, 1,
Clinical Biomarkers ⓘ
BMD↑, 1, LDH↓, 1, LDH∅, 1,
Functional Outcomes ⓘ
toxicity↓, 2, toxicity↝, 2, Wound Healing↑, 1,
Total Targets: 36
Scientific Paper Hit Count for: eff, efficacy
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:49 Cells:% prod#:% Target#:961 State#:% Dir#:4
wNotes=0 sortOrder:rid,rpid
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