IL1α Cancer Research Results

IL1α, interleukin-1 alpha: Click to Expand ⟱
Source:
Type:
The term "IL-1" is often used as an umbrella term for the interleukin-1 family, which includes multiple cytokines. The two best-known members are IL-1α and IL-1β.
L-1α: Often expressed as a precursor that is biologically active even before processing; it can be active in its intracellular form and when expressed on the cell surface.
IL-1α is typically associated with cell damage and tends to act more locally.

High IL-1α levels have been detected in a number of tumor cells and have been associated with enhanced tumor invasion and metastasis in several settings.
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
4598- AgNPs,    In vivo human time-exposure study of orally dosed commercial silver nanoparticles
- in-vivo, Nor, NA
*toxicity∅, *Dose↝, *Dose↝, *BioAv↝, *BioAv↝, *H2O2∅, *IL8∅, *IL1α∅, *IL1β∅, *MCP1∅, *NQO1∅, *BioAv↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

H2O2∅, 1,   NQO1∅, 1,  

Immune & Inflammatory Signaling ⓘ

IL1α∅, 1,   IL1β∅, 1,   IL8∅, 1,   MCP1∅, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↝, 2,   Dose↝, 2,  

Functional Outcomes ⓘ

toxicity∅, 1,  
Total Targets: 10

Scientific Paper Hit Count for: IL1α, interleukin-1 alpha
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:977  State#:%  Dir#:6
  wNotes=0  sortOrder:rid,rpid

 

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