NHE1 Cancer Research Results

NHE1, Na+/H+ exchanger isoform 1: Click to Expand ⟱
Source:
Type:
Plays a crucial role in cancer cell proliferation and metastasis.
NHE1 is a ubiquitously expressed acid-extruding membrane transport protein, and upregulation of its expression and/or activity is commonly correlated with tumor malignancy.
EC, Endometrial Cancer: Click to Expand ⟱
Endometrial cancer (EC) is the most common gynecological cancer, and one of the most important causes of cancer-related deaths in women worldwide.
Scientific Papers found: Click to Expand⟱
1612- EA,    Negative Effect of Ellagic Acid on Cytosolic pH Regulation and Glycolytic Flux in Human Endometrial Cancer Cell
- in-vitro, EC, NA
NHE1↓, i-pH↓, ROS↓, GlucoseCon↓, NHE1↓, Glycolysis↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↓, 1,  

Core Metabolism/Glycolysis ⓘ

GlucoseCon↓, 1,   Glycolysis↓, 1,  

Barriers & Transport ⓘ

NHE1↓, 2,  

Cellular Microenvironment ⓘ

i-pH↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: NHE1, Na+/H+ exchanger isoform 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:52  Cells:%  prod#:%  Target#:474  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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