BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.


CRC, Colorectal Cancer: Click to Expand ⟱
Colorectal cancer is a broader term that encompasses both colon and rectal cancer.


Scientific Papers found: Click to Expand⟱
2678- BBR,    Berberine as a Potential Agent for the Treatment of Colorectal Cancer
- Review, CRC, NA
*Inflam↓, *antiOx↑, *cardioP↑, *neuroP↑, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDC2↓, AMPK↝, mTOR↝, Casp8↑, Casp9↑, Cyt‑c↑, TumCMig↓, TumCI↓, EMT↓, MMPs↓, E-cadherin↓, Telomerase↓, *toxicity↓, GRP78/BiP↓, EGFR↓, CDK4↓, COX2/PTGS2↓, PGE2↓, p‑JAK2↓, p‑STAT3↓, MMP2↓, MMP9↓, GutMicro↑, eff↝, *BioAv↓, BioAv↑,
5823- capec,    Capecitabine: a review
- Review, CRC, NA
eff↑, BioAv↑, eff↑,
5981- Chit,    Chitosan-Based Drug Delivery Systems for Targeted Chemotherapy in Colorectal Cancer: A Scoping Review
- Review, CRC, NA
DDS↑, eff↑, BioAv↑, BioEnh↑, eff↑,
7013- Fuc,    Fucoidan-based nanoparticles for colorectal cancer therapy: Mechanisms and preclinical insights
- Review, CRC, NA
*Inflam↓, *antiOx↑, AntiCan↑, BioAv↑, Apoptosis↑, angioG↓, Imm↝, ChemoSen↑, chemoP↑,
7641- Ins,    Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis
- Review, CRC, NA
AntiCan↑, p‑Akt↓, TF-Ag↓, *PI3K↓, *AP-1↓, *DNArepair↑, *BioAv↑, *BBB↑, *other↑, *PGE2↓,
8071- KAE,    Cellular reprogramming and signaling control by kaempferol in colorectal cancer
- Review, CRC, NA
*toxicity↓, Risk↓, MMPs↓, VEGF↓, VEGFR1↓, Wnt↓, β-catenin/ZEB1↑, PI3K↓, Akt↓, mTOR↓, ChemoSen↑, *BioAv↓, TumCCA↑, Apoptosis↑, Hif1a↓, ROS↑, TumCMig↓, TumMeta↓, PKM2↓, Glycolysis↓, DNAdam↑, HO-1↑, Ferroptosis↑, eff↑, Dose↝, BioAv↑,
3138- VitC,    The Hypoxia-inducible Factor Renders Cancer Cells More Sensitive to Vitamin C-induced Toxicity
- in-vitro, RCC, RCC4 - in-vitro, CRC, HCT116 - in-vitro, BC, MDA-MB-435 - in-vitro, Ovarian, SKOV3 - in-vitro, Colon, SW48 - in-vitro, GBM, U251
eff↑, Warburg↓, BioAv↑, ROS↑, DNAdam↑, ATP↓, eff↑, necrosis↑, PARP↑,

Showing Research Papers: 1 to 7 of 7

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

TF-Ag↓, 1,  

Redox & Oxidative Stress(tgid=1)

Ferroptosis↑, 1,   HO-1↑, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics(tgid=3)

ATP↓, 1,   CDC2↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

AMPK↝, 1,   Glycolysis↓, 1,   PKM2↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5)

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↑, 2,   Casp8↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,   Ferroptosis↑, 1,   necrosis↑, 1,   Telomerase↓, 1,  

Protein Folding & ER Stress(tgid=8)

GRP78/BiP↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 2,   PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

EMT↓, 1,   mTOR↓, 1,   mTOR↝, 1,   PI3K↓, 1,   p‑STAT3↓, 1,   Wnt↓, 1,  

Migration(tgid=13)

E-cadherin↓, 1,   MMP2↓, 1,   MMP9↓, 1,   MMPs↓, 2,   TumCI↓, 1,   TumCMig↓, 2,   TumMeta↓, 1,   VEGFR1↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   EGFR↓, 1,   Hif1a↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2/PTGS2↓, 1,   Imm↝, 1,   p‑JAK2↓, 1,   PGE2↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 6,   BioEnh↑, 1,   ChemoSen↑, 2,   DDS↑, 1,   Dose↝, 1,   eff↑, 7,   eff↝, 1,  

Clinical Biomarkers(tgid=22)

EGFR↓, 1,   GutMicro↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   chemoP↑, 1,   Risk↓, 1,  
Total Targets: 61

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 2,  

Transcription & Epigenetics(tgid=7)

other↑, 1,  

DNA Damage & Repair(tgid=10)

DNArepair↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

PI3K↓, 1,  

Migration(tgid=13)

AP-1↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 2,   PGE2↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 2,   BioAv↑, 1,  

Functional Outcomes(tgid=23)

cardioP↑, 1,   neuroP↑, 1,   toxicity↓, 2,  
Total Targets: 13

Scientific Paper Hit Count for: BioAv, bioavailability
1 Berberine
1 capecitabine
1 chitosan
1 Fucoidan
1 Inositol
1 Kaempferol
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:6  Cells:%  prod#:%  Target#:792  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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