eff Cancer Research Results

eff, efficacy: Click to Expand ⟱

Source:

Type:

Power to enhance an anti cancer effect

CRC, Colorectal Cancer: Click to Expand ⟱

Colorectal cancer is a broader term that encompasses both colon and rectal cancer.

Scientific Papers found: Click to Expand⟱

5278-

3BP,

effect-of-3-bromopyruvate-on-human-colorectal">The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression

in-vitro,

CRC,

HCT116

in-vitro,

CRC,

Caco-2

in-vitro,

CRC,

SW48

ATP↓, TumCD↑, selectivity↑, toxicity↓, OS↑, HK2?, Cyt‑c↑, eff↑, p‑Akt↑,

5263-

3BP,

CET,

3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis

in-vitro,

CRC,

DLD1

NA,

HCT116

eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1/ATG6↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT/SLC7A11↑, GSH↓, eff↓, MDA↑,

4774-

5-FU,

TQ,

CoQ10,

Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation

in-vitro,

CRC,

AntiCan↑, TumCCA↑, Apoptosis↑, eff↑, Bcl-2↓, survivin↓, P21↑, p27/CDKN1B↑, BAX↑, Cyt‑c↑, Casp3↑, PI3K↓, Akt↓, mTOR↓, Hif1a↓, PTEN↑, AMPKα↑, PDH↑, LDHA↓, antiOx↓, ROS↑, AntiCan↑,

5469-

AF,

Ligand supplementation restores the cancer therapy efficacy of the antirheumatic drug auranofin from serum inactivation

in-vitro,

CRC,

HCT116

eff↑, Half-Life↑,

4403-

AgNPs,

Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment

in-vitro,

GBM,

U251

in-vitro,

GBM,

U87MG

in-vitro,

GBM,

GL26

in-vitro,

Cerv,

HeLa

in-vitro,

CRC,

RKO

AntiCan↑, eff↑, EPR↑, selectivity↑, ROS↑, Casp↑, Apoptosis↑, DNAdam↑, tumCV↓, eff↑,

4412-

AgNPs,

Biosynthesis and characterization of silver nanoparticles from Asplenium dalhousiae and their potential biological properties

in-vitro,

CRC,

HCT116

in-vitro,

Melanoma,

A2780S

Bacteria↓, antiOx↑, AntiCan↑, eff↑,

4362-

AgNPs,

Enhancing Colorectal Cancer Radiation Therapy Efficacy using Silver Nanoprisms Decorated with Graphene as Radiosensitizers

in-vitro,

CRC,

HCT116

18–45 nm.

in-vitro,

CRC,

HT29

in-vivo,

NA,

Male Swiss nu/nu mice aged 5–8 weeks

eff↑, TumCG↓, OS↑, RadioS↑, eff↑, ROS↑, DNAdam↑, eff↝,

4379-

AgNPs,

Exposure to silver nanoparticles induces size- and dose-dependent oxidative stress and cytotoxicity in human colon carcinoma cells

in-vitro,

CRC,

LoVo

eff↑, TumCD↑, ROS↑, Bacteria↓,

4561-

AgNPs,

VitC,

Cellular Effects Nanosilver on Cancer and Non-cancer Cells: Potential Environmental and Human Health Impacts

in-vitro,

CRC,

HCT116

in-vitro,

Nor,

HEK293

NRF2↑, TumCCA↑, ROS↑, selectivity↑, *AntiViral↑, *toxicity↝, ETC↓, MMP↓, DNAdam↑, Apoptosis↑, lipid-P↑, other↝, UPR↑, *GRP78/BiP↑, *p‑PERK↑, *cl‑eIF2α↑, *CHOP/DDIT3↑, *JNK↑, Hif1a↓, AntiCan↑, *toxicity↓, eff↑,

5142-

AgNPs,

Biosynthesized Protein-Capped Silver Nanoparticles Induce ROS-Dependent Proapoptotic Signals and Prosurvival Autophagy in Cancer Cells

in-vitro,

CRC,

HUH7

220 and 249 nm

ROS↑, Apoptosis↑, eff↑, ChemoSen↑, EPR↑, Casp↑, MAPK↑,

1351-

And,

MEL,

Impact of Andrographolide and Melatonin Combinatorial Drug Therapy on Metastatic Colon Cancer Cells and Organoids

in-vitro,

CRC,

T84

in-vitro,

CRC,

COLO205

in-vitro,

CRC,

HT-29

in-vitro,

CRC,

DLD1

eff↑, Ki-67↓, Casp3↑, ER Stress↑, ROS↑, BAX↑, XBP-1↑, CHOP/DDIT3↑, eff↑,

5381-

ART/DHA,

Artemisitene triggers calcium-dependent ferroptosis by disrupting the LSH-EWSR1 interaction in colorectal cancer

in-vitro,

CRC,

HCT116

in-vitro,

Nor,

NCM460

in-vitro,

CRC,

HT29

in-vitro,

CRC,

HCT8

Ferroptosis↑, CYP24A1↓, Ca+2↑, SCD1↓, FAO↑, lipid-P↑, eff↑, selectivity↑, other?,

5376-

ART/DHA,

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis

in-vitro,

CRC,

HCT116

in-vitro,

CRC,

HT29

in-vitro,

CRC,

SW48

in-vitro,

BC,

MDA-MB-453

Ferroptosis↑, Ferritin↓, Iron↑, eff↑, TumAuto↑, LC3II↑, ROS↑,

2573-

ART/DHA,

effects_of_halofuginone_and_artemisinin_in_colorectal_cancer_cells">Cell death mechanisms induced by synergistic effects of halofuginone and artemisinin in colorectal cancer cells

in-vitro,

CRC,

HCT116

eff↑,

2582-

ART/DHA,

5-ALA,

Mechanistic Investigation of the Specific Anticancer Property of Artemisinin and Its Combination with Aminolevulinic Acid for Enhanced Anticolorectal Cancer Activity

in-vivo,

CRC,

HCT116

mouse xenograft CRC model

in-vitro,

CRC,

HCT116

eff↑, ROS↑, selectivity↑, TumCG↓, toxicity↓,

1360-

Ash,

immuno,

Withaferin A Increases the Effectiveness of Immune Checkpoint Blocker for the Treatment of Non-Small Cell Lung Cancer

in-vitro,

Lung,

H1650

in-vitro,

Lung,

A549

in-vitro,

CRC,

HCT116

in-vitro,

BC,

MDA-MB-231

in-vivo,

NA,

mice

PD-L1↑, eff↓, ROS↑, ER Stress↑, Apoptosis↑, BAX↑, Bak↑, BAD↑, Bcl-2↓, XIAP↓, survivin↓, cl‑PARP↑, CHOP/DDIT3↑, p‑eIF2α↑, ICD↑, eff↑,

1451-

Bos,

Phytochemical Analysis and Anti-cancer Investigation of Boswellia serrata Bioactive Constituents In Vitro

in-vitro,

CRC,

HepG2

1.58 and 5.82 μg/mL at 48 h

HepG2 cell line, extracts 1 and 2

in-vitro,

CRC,

HCT116

eff↑,

5866-

CA,

Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells

in-vitro,

CRC,

HCT116

in-vitro,

Colon,

SW480

in-vitro,

Colon,

HT29

tumCV↓, Apoptosis↑, P53↑, BAX↑, MDM2↓, Bcl-2↓, Bcl-xL↓, Casp9↑, Casp3↑, cl‑PARP↑, STAT3↓, survivin↓, cycD1/CCND1↓, CycD3↓, ROS↑, eff↓, eff↑,

1518-

CAP,

Capsaicin-mediated tNOX (ENOX2) up-regulation enhances cell proliferation and migration in vitro and in vivo

in-vitro,

CRC,

HCT116

ENOX2↑, TumCP↑, TumCMig↑, Dose?, eff↑,

5823-

capec,

Capecitabine: a review

Review,

CRC,

eff↑, BioAv↑, eff↑,

5968-

CET,

Cetuximab as a Key Partner in Personalized Targeted Therapy for Metastatic Colorectal Cancer

in-vitro,

CRC,

eff↑, Half-Life↑, Half-Life↑, EGFR↓, OS↑, QoL↑, eff↑, KRAS↓,

5967-

CET,

FDA grants accelerated approval to adagrasib with cetuximab for KRAS G12C-mutated colorectal cancer

Study,

CRC,

eff↑, Dose↝,

5981-

Chit,

Chitosan-Based Drug Delivery Systems for Targeted Chemotherapy in Colorectal Cancer: A Scoping Review

Review,

CRC,

DDS↑, eff↑, BioAv↑, BioEnh↑, eff↑,

7414-

CS,

Pro-Apoptotic Activity of Artichoke Leaf Extracts in Human HT-29 and RKO Colon Cancer Cells

in-vitro,

Colon,

HT29

in-vitro,

CRC,

RKO

*antiOx↑, *Inflam↓, tumCV↓, TumCCA↑, Apoptosis↑, eff↑,

3578-

CUR,

SIL,

Curcumin, but not its degradation products, in combination with silibinin is primarily responsible for the inhibition of colon cancer cell proliferation

in-vitro,

CRC,

DLD1

eff↑, BioAv↓, TumCG↓,

1878-

DCA,

5-FU,

Synergistic Antitumor Effect of Dichloroacetate in Combination with 5-Fluorouracil in Colorectal Cancer

in-vitro,

CRC,

LS174T

57mM

in-vitro,

CRC,

LoVo

29mM

in-vitro,

CRC,

SW-620

38mM

in-vitro,

CRC,

HT-29

47mM

tumCV↓, eff↑, PDKs↓, lactateProd↓, Glycolysis↓, mitResp↑, TumCCA↑, Bcl-2↓, BAX↑, Casp3↑,

1884-

DCA,

Sal,

Dichloroacetate and Salinomycin Exert a Synergistic Cytotoxic Effect in Colorectal Cancer Cell Lines

in-vitro,

CRC,

DLD1

in-vitro,

CRC,

HCT116

eff↑, pH↓, PDKs↓, Warburg↓,

1885-

DCA,

Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate

in-vitro,

CRC,

HCT116

These three cell lines do not express SLC5A8

in-vitro,

CRC,

SW-620

in-vitro,

CRC,

HT-29

SMCT1∅, eff↓, eff↑, eff↑, PDKs↓, MMP↓, Glycolysis↓, mitResp↑, ROS↑, eff↑,

6745-

DHA,

Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells

in-vitro,

CRC,

HT29

tumCV↓, selectivity↑, Ferroptosis↑, lipid-P↑, mt-ROS↑, ChemoSen↑, *toxicity↓, TumCG↓, eff↑, eff↑, Dose↝, mtDam↑, *Inflam↓, *chemoP↑, Dose↑,

1850-

dietFMD,

Fasting-mimicking diet remodels gut microbiota and suppresses colorectal cancer progression

in-vivo,

CRC,

mice

TumCP↑, angioG↓, CD8+↑, GutMicro↑, eff↑,

1896-

dietMet,

Dietary methionine links nutrition and metabolism to the efficacy of cancer therapies

in-vivo,

CRC,

mice

TumCG↓, *GSH↓, RadioS↑, eff↑,

6730-

Dipy,

ASA,

Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner

vitro+vivo,

CRC,

CRC mouse models, i.e. an orthotopic xenograft mouse model,

*AntiThr↑, eff↑, ER Stress↑, UPR↑, *AntiAg↑, *COX1↓, Risk↓, TumCG↓, Apoptosis↑, HMG-CoA↓, *Inflam↓, *antiOx↓,

6607-

Ech,

Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines

in-vitro,

PC,

MIA PaCa-2

in-vitro,

CRC,

Colo320

tumCV↓, eff↑, Apoptosis↑, Casp3↑, Casp7↑, DNAdam↑, Imm↑, NK cell↑, PGE2↓, COX1↓, COX2/PTGS2↓, 5LO↓,

3241-

EGCG,

Epigallocatechin gallate triggers apoptosis by suppressing de novo lipogenesis in colorectal carcinoma cells

in-vitro,

CRC,

HCT116

0.5 ± 0.05 mm

in-vitro,

CRC,

HT29

0.8 ± 0.06 mm

in-vitro,

Liver,

HepG2

 > 1 mm

in-vitro,

Liver,

HUH7

 > 1 mm

tumCV↓, mtDam↑, Apoptosis↑, ATP↓, lipoGen↓, eff↑,

684-

EGCG,

effect_of_EGCG_in_colorectal_cancer_cells_by_blocking_EGCG-induced_YAP_activation">Improving the anti-tumor effect of EGCG in colorectal cancer cells by blocking EGCG-induced YAP activation

in-vitro,

CRC,

eff↑, Akt↓, VEGFR2/KDR/Flk1↓, STAT3↓, P53↓, Hippo↓, YAP/TEAD↑,

6391-

Eug,

BCP,

5-FU,

Exploring Mechanism of Actions for Eugenol and Beta-Caryophyllene to Combat Colorectal Cancer Chemotherapy Using Network Pharmacology

in-vitro,

CRC,

HCT116

eff↑, ChemoSen↑, HSP90↓, Dose↝, TumAuto↑, Apoptosis↑, PI3K↓, Akt↓, mTOR↓, JNK↓, p38↓, EMT↓,

6960-

FA,

VitA,RetA,

VitC,

VitD3,

VitE

Dietary supplement use and colorectal cancer risk: a systematic review and meta-analyses of prospective cohort studies

Review,

CRC,

Risk∅, eff↑,

6918-

FIS,

Geld,

Radic,

HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells

in-vitro,

CRC,

COLO205

eff↑, cl‑Casp3↑, PARP↑, MMPs↓, cl‑Casp9↑, other↝,

7001-

Fuc,

Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer

Trial,

CRC,

 20 patients with unresectable advanced or recurrent colorectal cancer

fatigue↓, eff↑, OS↑,

4523-

HNK,

MAG,

BA,

Honokiol-Magnolol-Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti-PD-1 Immunotherapy in Colorectal Cancer by Triggering GSDME-Dependent Pyroptosis

in-vitro,

CRC,

HCT116

in-vitro,

CRC,

LoVo

in-vivo,

CRC,

HCT116

mice

AntiCan↑, eff↑, TumCP↓, TumCCA↓, cycD1/CCND1↓, Pyro↑, Apoptosis↑, cl‑GSDME↑, Bcl-2↓, Cyt‑c↑, Casp9↑, TumCG↓,

8033-

IVM,

dietMet,

rMETase,

Direct comparison of efficacy of combining ivermectin versus five first-line chemotherapy drugs with recombinant methioninase against colon-cancer cells

in-vitro,

CRC,

HCT116

eff↑, ChemoSen↑, eff↑, selectivity↑, eff↑, TumCCA↑,

8002-

JG,

Identification and Biological Evaluation of Juglone-Derived STAT3 Inhibitors against Colorectal Cancer

in-vitro,

PC,

in-vitro,

CRC,

eff↑, STAT3↓, TumCP↓, selectivity↑,

2390-

KAE,

Kaempferol Can Reverse the 5-Fu Resistance of Colorectal Cancer Cells by Inhibiting PKM2-Mediated Glycolysis

in-vitro,

CRC,

HCT8

eff↑, GlucoseCon↓, lactateProd↓, PKM2↓, Glycolysis↓, glucose↑,

8071-

KAE,

Cellular reprogramming and signaling control by kaempferol in colorectal cancer

Review,

CRC,

*toxicity↓, Risk↓, MMPs↓, VEGF↓, VEGFR1↓, Wnt↓, β-catenin/ZEB1↑, PI3K↓, Akt↓, mTOR↓, ChemoSen↑, *BioAv↓, TumCCA↑, Apoptosis↑, Hif1a↓, ROS↑, TumCMig↓, TumMeta↓, PKM2↓, Glycolysis↓, DNAdam↑, HO-1↑, Ferroptosis↑, eff↑, Dose↝, BioAv↑,

8072-

KAE,

Natural defense against colorectal cancer: the effects of kaempferol on epigenetics, apoptosis, inflammation, oxidative stress, and cell proliferation

Review,

CRC,

AntiCan↑, TumCP↓, TumCI↓, Inflam↓, angioG↓, ROS↑, Apoptosis↑, ChemoSen↑, Risk↓, *antiOx↑, *Inflam↓, *AntiBio↑, *cardioP↑, *neuroP↑, selectivity↑, PUMA↑, Cyt‑c↑, cl‑Casp3↑, cl‑PARP↑, Apoptosis↑, NF-kB↓, COX2/PTGS2↓, CC(CDKs/cyclins)↓, TumCCA↑, BioAv↓, eff↑, DR4↑, DR5↑, Casp3↑, Casp9↑, Casp7↑, TumCP↓, TumCI↓, TumAuto↑, mtDam↑, P53↑, MAPK↑, *lipid-P↓, *TAC↑, *Catalase↑, *SOD↑, *GPx↑, *NRF2↑,

8122-

LA,

ProBio,

Probiotics in colorectal cancer: mechanisms, biomarkers, and adjunct strategies

Review,

CRC,

GutMicro↑, IBI↑, TumCG↓, Inflam↓, Imm↝, eff↑,

8189-

LGE,

Lemongrass Extract Possesses Potent Anticancer Activity Against Human Colon Cancers, Inhibits Tumorigenesis, Enhances Efficacy of FOLFOX, and Reduces Its Adverse Effects

vitro+vivo,

CRC,

Apoptosis↑, Dose↝, selectivity↑, eff↑,

595-

MFrot,

VitC,

MF,

The Effect of Alternating Magnetic Field Exposure and Vitamin C on Cancer Cells

in-vitro,

PC,

MIA PaCa-2

4mT, 1000rpm

51% reduction

reduces IC50 value of cells treated with Vit C and magnetic field

in-vitro,

CRC,

SW-620

23% reduction

in-vitro,

NA,

HT1080

37% reduction

in-vitro,

Pca,

PC3

40% reduction

in-vitro,

OS,

U2OS

46% reduction

in-vitro,

BC,

MCF7

33% reduction

in-vitro,

Nor,

CCD-18Co

-7% reduction

health normal colon cells *****

TumCD↑, eff↑, *TumCG∅,

2070-

PB,

Phenylbutyrate-induced apoptosis is associated with inactivation of NF-kappaB IN HT-29 colon cancer cells

in-vitro,

CRC,

HT-29

TumCG↓, Apoptosis↑, MMP↓, Casp3↑, PARP↓, NF-kB↓, eff↑,

1678-

PBG,

5-FU,

sericin,

In vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/AKT/mTOR pathway

in-vitro,

CRC,

Caco-2

in-vivo,

NA,

105 in bred- albino mice

PI3K↓, Akt↓, mTOR↓, TumCP↓, Bcl-2↓, BAX↑, Casp3↑, Casp9↑, ROS↓, FOXO1↑, *toxicity∅, eff↑,

Showing Research Papers: 1 to 50 of 63
Page 1 of 2 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 63

Pathway results for Effect on Cancer / Diseased Cells:

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 2, CD8+↑, 1,
Total Targets: 166

Pathway results for Effect on Normal Cells:

NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1, antiOx↑, 2, Catalase↑, 1, GPx↑, 1, GSH↓, 1, lipid-P↓, 1, NRF2↑, 1, SOD↑, 1, TAC↑, 1,

Cell Death(tgid=5) ⓘ

JNK↑, 1,

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1, cl‑eIF2α↑, 1, GRP78/BiP↑, 1, p‑PERK↑, 1,

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG∅, 1,

Migration(tgid=13) ⓘ

AntiAg↑, 1,

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1, Inflam↓, 4,

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,

Functional Outcomes(tgid=23) ⓘ

cardioP↑, 1, chemoP↑, 1, neuroP↑, 1, toxicity↓, 3, toxicity↝, 1, toxicity∅, 1,

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,
Total Targets: 28

Scientific Paper Hit Count for: eff, efficacy

6 Silver-NanoParticles
5 5-fluorouracil
5 Vitamin C (Ascorbic Acid)
4 cetuximab
4 Artemisinin
3 Dichloroacetate
3 Kaempferol
2 3-bromopyruvate
2 chitosan
2 diet Methionine-Restricted Diet
2 EGCG (Epigallocatechin Gallate)
2 Vitamin D3
2 Piperlongumine
2 Sulforaphane (mainly Broccoli)
1 Thymoquinone
1 Coenzyme Q10
1 Auranofin
1 Andrographis
1 Melatonin
1 5-Aminolevulinic acid
1 Ashwagandha(Withaferin A)
1 immunotherapy
1 Boswellia (frankincense)
1 Carnosic acid
1 Capsaicin
1 capecitabine
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 Curcumin
1 Silymarin (Milk Thistle) silibinin
1 salinomycin
1 Docosahexaenoic Acid
1 diet FMD Fasting Mimicking Diet
1 Dipyridamole
1 Aspirin
1 Echinacea
1 Eugenol
1 Beta-Caryophyllene
1 Folic Acid, Vit B9
1 Vitamin A, Retinoic Acid
1 Vitamin E
1 Fisetin
1 Geldanamycin
1 Radicicol/monorden
1 Fucoidan
1 Honokiol
1 Magnolol
1 Baicalin
1 Ivermectin
1 Recombinant Methioninase
1 Juglone
1 Lactobacillus
1 probiotics
1 Lemongrass Extract/Citral
1 Magnetic Field Rotating
1 Magnetic Fields
1 Phenylbutyrate
1 Propolis -bee glue
1 sericin
1 Phenethyl isothiocyanate
1 Parthenolide
1 Sulfasalazine
1 Cisplatin
1 Selenium NanoParticles
1 Shikonin
1 Terpinen-4-ol / Tea Tree Oil
1 Aflavin-3,3′-digallate

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:6  Cells:%  prod#:%  Target#:961  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

eff Cancer Research Results

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress(tgid=1) ⓘ

Metal & Cofactor Biology(tgid=2) ⓘ

Mitochondria & Bioenergetics(tgid=3) ⓘ

Core Metabolism/Glycolysis(tgid=4) ⓘ

Cell Death(tgid=5) ⓘ

Kinase & Signal Transduction(tgid=6) ⓘ

Transcription & Epigenetics(tgid=7) ⓘ

Protein Folding & ER Stress(tgid=8) ⓘ

Autophagy & Lysosomes(tgid=9) ⓘ

DNA Damage & Repair(tgid=10) ⓘ

Cell Cycle & Senescence(tgid=11) ⓘ

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Migration(tgid=13) ⓘ

Angiogenesis & Vasculature(tgid=14) ⓘ

Barriers & Transport(tgid=15) ⓘ

Immune & Inflammatory Signaling(tgid=16) ⓘ

Cellular Microenvironment(tgid=17) ⓘ

Hormonal & Nuclear Receptors(tgid=20) ⓘ

Drug Metabolism & Resistance(tgid=21) ⓘ

Clinical Biomarkers(tgid=22) ⓘ

Functional Outcomes(tgid=23) ⓘ

Infection & Microbiome(tgid=24) ⓘ

Pathway results for Effect on Normal Cells:

NA, unassigned(tgid=0) ⓘ

Redox & Oxidative Stress(tgid=1) ⓘ

Cell Death(tgid=5) ⓘ

Transcription & Epigenetics(tgid=7) ⓘ

Protein Folding & ER Stress(tgid=8) ⓘ

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Migration(tgid=13) ⓘ

Immune & Inflammatory Signaling(tgid=16) ⓘ

Drug Metabolism & Resistance(tgid=21) ⓘ

Functional Outcomes(tgid=23) ⓘ

Infection & Microbiome(tgid=24) ⓘ

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