| Source: |
| Type: |
| Drug dosage vs efficacy, and actual dosage number of research papers. |
| Colorectal cancer is a broader term that encompasses both colon and rectal cancer. |
| 5263- | 3BP, | CET, | 3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis |
| - | in-vitro, | CRC, | DLD1 | - | NA, | NA, | HCT116 |
| 5410- | ASA, | Low-Dose Aspirin and the Prevention of Colorectal Cancer in Inflammatory Bowel Disease: A Nationwide Cohort Study |
| - | Study, | CRC, | NA |
| 5404- | ASA, | Low-Dose Aspirin and Prevention of Colorectal Cancer: Evidence From a Nationwide Registry-Based Cohort in Norway |
| - | Study, | CRC, | NA |
| 5406- | ASA, | Adjuvant aspirin therapy and colorectal cancer survival |
| - | Trial, | CRC, | NA |
| 5407- | ASA, | Low-dose aspirin reduces the risk of colorectal cancer recurrence in patients with resected PI3K-altered localised disease, according to the ALASCCA trial. |
| - | Trial, | CRC, | NA |
| 6518- | BCP, | beta-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models |
| - | vitro+vivo, | CRC, | HCT116 |
| 2734- | BetA, | Betulinic Acid Modulates the Expression of HSPA and Activates Apoptosis in Two Cell Lines of Human Colorectal Cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 |
| 5917- | Cats, | Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial |
| - | Trial, | CRC, | NA |
| 6615- | Cen, | Asiaticoside suppresses cell proliferation by inhibiting the NF-κB signaling pathway in colorectal cancer |
| - | vitro+vivo, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | LoVo |
| 5970- | CET, | Cetuximab |
| - | Review, | CRC, | NA | - | Review, | HNSCC, | NA |
| 5967- | CET, | FDA grants accelerated approval to adagrasib with cetuximab for KRAS G12C-mutated colorectal cancer |
| - | Study, | CRC, | NA |
| 7163- | CHA, | The anticancer effects of chaetocin are independent of programmed cell death and hypoxia, and are associated with inhibition of endothelial cell proliferation |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | OS, | U2OS | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HeLa | - | in-vivo, | Ovarian, | SKOV3 |
| 7445- | CYN, | Cynaropicrin Shows Antitumor Progression Potential in Colorectal Cancer Through Mediation of the LIFR/STATs Axis |
| - | vitro+vivo, | CRC, | RKO | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | DLD1 |
| 6745- | DHA, | Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells |
| - | in-vitro, | CRC, | HT29 |
| 6318- | DRE, | Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways |
| - | vitro+vivo, | CRC, | HCT116 | - | NA, | Nor, | NCM460 |
| 6391- | Eug, | BCP, | 5-FU, | Exploring Mechanism of Actions for Eugenol and Beta-Caryophyllene to Combat Colorectal Cancer Chemotherapy Using Network Pharmacology |
| - | in-vitro, | CRC, | HCT116 |
| 6846- | EVO, | Evodiamine Inhibits Colorectal Cancer Growth via RTKs Mediated PI3K/AKT/p53 Signaling Pathway |
| - | in-vitro, | CRC, | HT29 | - | in-vitro, | CRC, | HCT116 |
| 7014- | Fuc, | 5-FU, | Low-Molecular-Weight Fucoidan as Complementary Therapy of Fluoropyrimidine-Based Chemotherapy in Colorectal Cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Colon, | Caco-2 |
| 6567- | Ger, | Geraniin inhibits proliferation and induces apoptosis through inhibition of phosphatidylinositol 3-kinase/Akt pathway in human colorectal cancer in vitro and in vivo |
| - | vitro+vivo, | CRC, | SW480 | - | in-vitro, | CRC, | HT29 |
| 7245- | Gink, | Ginkgetin inhibits the growth of DU-145 prostate cancer cells through inhibition of signal transducer and activator of transcription 3 activity |
| - | vitro+vivo, | Pca, | DU145 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Nor, | MCF10 |
| 7258- | Gink, | Ginkgetin inhibits the growth of DU−145 prostate cancer cells through inhibition of signal transducer and activator of transcription 3 activity |
| - | vitro+vivo, | Pca, | DU145 | - | in-vitro, | CRC, | HCT116 |
| 2505- | H2, | Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis |
| - | Trial, | CRC, | NA |
| 7357- | HibSad, | Hibiscus Anthocyanins Extracts Induce Apoptosis by Activating AMP-Activated Protein Kinase in Human Colorectal Cancer Cells |
| - | in-vitro, | CRC, | LoVo |
| 7461- | HNK, | Honokiol: a potent chemotherapy candidate for human colorectal carcinoma |
| - | vitro+vivo, | CRC, | RKO |
| 7540- | HT, | Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G1/S cell cycle arrest in human colorectal cancer cells via ROS generation |
| - | in-vitro, | CRC, | HCT8 | - | in-vitro, | CRC, | HCT116 |
| 7539- | HT, | Polyphenols Extracts from Oil Production Waste Products (OPWPs) Reduce Cell Viability and Exert Anti-Inflammatory Activity via PPARγ Induction in Colorectal Cancer Cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | LoVo |
| 7721- | IP6, | Ins, | Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma |
| - | in-vitro, | CRC, | HT-29 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | SW-620 |
| 7702- | IP6, | Ins, | capec, | Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model |
| - | in-vivo, | CRC, | NA |
| 8025- | IVM, | Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth |
| - | in-vitro, | CRC, | SW480 | - | in-vivo, | CRC, | HCT116 |
| 8052- | IVM, | rMETase, | Selective Synergy of Ivermectin Combined With Recombinant Methioninase Against Colon-Cancer Cells in Contrast to Normal Fibroblasts |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Nor, | Hs27 |
| 8071- | KAE, | Cellular reprogramming and signaling control by kaempferol in colorectal cancer |
| - | Review, | CRC, | NA |
| 8074- | KAE, | Dose-dependent tuning of HSP70-Beclin-1 by kaempferol governs autophagy and chemosensitivity |
| - | in-vitro, | SCC, | KYSE150 | - | in-vitro, | SCC, | KYSE450 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Liver, | HepG2 | - | in-vitro, | Cerv, | HeLa | - | in-vitro, | Lung, | A549 |
| 8079- | KAE, | Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Kaempferol in Colorectal Cancer Cells |
| - | in-vitro, | CRC, | DLD1 | - | in-vitro, | Lung, | A549 | - | in-vitro, | Liver, | HUH7 | - | in-vitro, | Cerv, | HeLa |
| - | Trial, | CRC, | NA |
| - | Trial, | CRC, | NA |
| 8123- | LF, | Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps in a randomized, placebo-controlled clinical trial |
| - | Trial, | CRC, | NA |
| 8124- | LF, | Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine |
| - | Trial, | CRC, | NA |
| 8129- | LF, | Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy |
| - | Trial, | CRC, | NA |
| 8189- | LGE, | Lemongrass Extract Possesses Potent Anticancer Activity Against Human Colon Cancers, Inhibits Tumorigenesis, Enhances Efficacy of FOLFOX, and Reduces Its Adverse Effects |
| - | vitro+vivo, | CRC, | NA |
| 5599- | NaHCO3, | Acidity generated by the tumor microenvironment drives local invasion |
| - | in-vivo, | BC, | MDA-MB-231 | - | in-vitro, | CRC, | HCT116 |
| 1695- | Se, | Serum Selenium Concentration as a Potential Diagnostic Marker for Early-Stage Colorectal Cancer: A Comparative Study |
| - | Trial, | CRC, | NA |
| 4495- | Se, | Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort |
| - | Study, | CRC, | NA |
| 4734- | SeNPs, | CPT-11, | Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles |
| - | in-vitro, | CRC, | HCT8 | - | in-vivo, | NA, | NA |
| 4470- | SeNPs, | Chit, | Synthesis and cytotoxic activities of selenium nanoparticles incorporated nano-chitosan |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Liver, | HepG2 | - | in-vitro, | BC, | MCF7 |
| 1501- | SFN, | The Inhibitory Effect of Sulforaphane on Bladder Cancer Cell Depends on GSH Depletion-Induced by Nrf2 Translocation |
| - | in-vitro, | CRC, | T24/HTB-9 |
| 2361- | SK, | Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer |
| - | in-vivo, | CRC, | NA |
| 2007- | SK, | Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells |
| - | in-vitro, | lymphoma, | U937 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | SkBr3 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | OS, | U2OS | - | NA, | Nor, | RPE-1 |
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:6 Cells:% prod#:% Target#:1114 State#:% Dir#:4
wNotes=0 sortOrder:rid,rpid