STAT4 Cancer Research Results

STAT4, Signal transducer and activator of transcription 4: Click to Expand ⟱

Source:

Type:

STAT4 (Signal Transducer and Activator of Transcription 4) is a transcription factor that plays a significant role in the immune response and has been implicated in various biological processes, including inflammation and cell proliferation.
High STAT4 expression has been associated with improved prognosis and reduced metastasis.

Diabetic, Diabetic: Click to Expand ⟱

Diabetic

Scientific Papers found: Click to Expand⟱

2690-

BBR,

Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice

in-vivo,

Diabetic,

berberine (Sigma, 200 mg/kg body weight), by gavage, daily for 2 weeks

11-week-old female NOD mice

*Inflam↓, *Th17↓, *Th1 response↓, *ERK↑, *p38↓, *JNK↓, *STAT1↓, *STAT4↓, *MAPK↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Cell Death ⓘ

JNK↓, 1, MAPK↓, 1, p38↓, 1,

Proliferation, Differentiation & Cell State ⓘ

ERK↑, 1, STAT1↓, 1, STAT4↓, 1,

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1, Th1 response↓, 1, Th17↓, 1,
Total Targets: 9

Scientific Paper Hit Count for: STAT4, Signal transducer and activator of transcription 4

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells