Database Query Results : , ,

TLS, Tumor Lysis Syndrome: Click to Expand ⟱
Tumor lysis syndrome occurs when large numbers of cancer cells die rapidly, releasing their contents—including potassium, phosphate, and nucleic acids—into the bloodstream. This sudden release can overwhelm the body’s ability to metabolize and excrete these substances, leading to potentially life-threatening electrolyte imbalances and metabolic disturbances.
Key features of TLS include:
• Hyperkalemia: Elevated potassium levels, which can affect heart function.
• Hyperphosphatemia: Increased phosphate levels, potentially leading to hypocalcemia.
• Hypocalcemia: Low calcium levels, which can cause neuromuscular irritability and cardiac issues.
• Hyperuricemia: Elevated uric acid levels from the breakdown of nucleic acids, which may lead to kidney problems.

TLS is managed proactively in high-risk patients with hydration, medications like allopurinol or rasburicase to reduce uric acid levels, and close monitoring of electrolyte levels.

Some studies have suggested that cherries might help lower uric acid levels in gout patients.
Alkaline diets: There is some discussion about diets that promote urinary alkalinization helping excrete uric acid.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:68  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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