TumCP Cancer Research Results

TumCP, Tumor Cell proliferation: Click to Expand ⟱
Source:
Type:
Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors.


MM, Malignant Mesothelioma: Click to Expand ⟱
Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs. The area most commonly affected is the lining of the lungs and chest wall.


Scientific Papers found: Click to Expand⟱
3167- Ash,    Withaferin A Inhibits the Proteasome Activity in Mesothelioma In Vitro and In Vivo
- in-vitro, MM, H226
TumCP↓, cMyc↓, cFos↓, cJun↓, TIMP2↑, Vim↓, ROS↑, BAX↑, IKKα↑, Casp3↑, cl‑PARP↑,
5750- CA,    Exploration of the anticancer properties of Caffeic Acid in malignant mesothelioma cells
- in-vitro, MM, NA
eff↑, selectivity↑, Ki-67↓, PCNA↓, TumCP↓, p‑ERK↓, Akt↓, p27↑, P21↑, TumCCA↑, Bax:Bcl2↑, cl‑Casp3↑, mt-Apoptosis↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

ROS↑, 1,  

Core Metabolism/Glycolysis

cMyc↓, 1,  

Cell Death

Akt↓, 1,   mt-Apoptosis↑, 1,   BAX↑, 1,   Bax:Bcl2↑, 1,   Casp3↑, 1,   cl‑Casp3↑, 1,   p27↑, 1,  

Transcription & Epigenetics

cJun↓, 1,  

DNA Damage & Repair

cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence

P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

cFos↓, 1,   p‑ERK↓, 1,  

Migration

Ki-67↓, 1,   TIMP2↑, 1,   TumCP↓, 2,   Vim↓, 1,  

Immune & Inflammatory Signaling

IKKα↑, 1,  

Drug Metabolism & Resistance

eff↑, 1,   selectivity↑, 1,  

Clinical Biomarkers

Ki-67↓, 1,  
Total Targets: 24

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TumCP, Tumor Cell proliferation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:70  Cells:%  prod#:%  Target#:327  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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