creat Cancer Research Results
creat, creatinine: Click to Expand ⟱
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Creatinine is fundamentally a metabolic waste product derived from creatine phosphate in muscle. Its blood levels are routinely used as a clinical biomarker to assess kidney function rather than a direct regulator of oncogenic processes.
Creatinine is a primary marker used to estimate the glomerular filtration rate (GFR).
-Elevated creatinine can be a sign of compromised kidney vascular function.
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Park, Parkinson's Disease (PD): Click to Expand ⟱
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, and is due to the degeneration of dopaminergic neurons. It is multifactorial, caused by genetic and environmental factors and currently has no definitive cure.
-CoQ10 deficiency was observed at a higher frequency in Parkinson's disease
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Scientific Papers found: Click to Expand⟱
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Review, |
AD, |
NA |
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Review, |
Var, |
NA |
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Review, |
Park, |
NA |
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Review, |
Stroke, |
NA |
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*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2↓, p‑FAK↓,
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Review, |
Nor, |
NA |
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NA, |
AD, |
NA |
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NA, |
Diabetic, |
NA |
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NA, |
Stroke, |
NA |
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NA, |
LiverDam, |
NA |
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NA, |
Park, |
NA |
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*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,
Showing Research Papers: 1 to 2 of 2
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSH↓, 1, ROS↑, 1,
Cell Death ⓘ
Bcl-2↓, 1, Casp12↑, 1, Casp3↑, 1, Casp8↑, 1, Casp9↑, 1, Cyt‑c↑, 1, Fas↑, 1, p38↑, 1,
DNA Damage & Repair ⓘ
CHK1↓, 1, P53↑, 1,
Cell Cycle & Senescence ⓘ
CycB/CCNB1↓, 1, P21↑, 1, TumCCA↑, 1,
Proliferation, Differentiation & Cell State ⓘ
STAT3↓, 1,
Migration ⓘ
p‑FAK↓, 1, TumCMig↓, 1,
Angiogenesis & Vasculature ⓘ
Hif1a↓, 1, VEGF↓, 1, VEGFR2↓, 1,
Immune & Inflammatory Signaling ⓘ
IL8↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, chemoP↑, 1,
Total Targets: 24
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 2, GSH↑, 1, GSTs↑, 1, Keap1↓, 1, lipid-P↓, 1, MDA↓, 1, MPO↓, 1, NRF2↑, 1, ROS↓, 3, SOD↑, 1, TBARS↓, 1,
Mitochondria & Bioenergetics ⓘ
mtDam↓, 1,
Core Metabolism/Glycolysis ⓘ
ALAT↓, 1, H2S↑, 1, LDH↓, 2, SIRT1↑, 1,
Cell Death ⓘ
Akt↓, 1, iNOS↓, 1,
Transcription & Epigenetics ⓘ
other↑, 1,
DNA Damage & Repair ⓘ
DNAdam↓, 1,
Proliferation, Differentiation & Cell State ⓘ
PI3K↓, 1,
Angiogenesis & Vasculature ⓘ
NO↓, 1,
Barriers & Transport ⓘ
BBB↑, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, IL6↓, 1, Inflam↓, 1, NF-kB↓, 1, PGE2↓, 1, TNF-α↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↑, 2, BioAv↝, 1, Dose↝, 1, eff↑, 4, Half-Life↝, 1,
Clinical Biomarkers ⓘ
ALAT↓, 1, AST↓, 1, BG↓, 1, BP↓, 1, creat↓, 2, GutMicro↑, 1, IL6↓, 1, LDH↓, 2,
Functional Outcomes ⓘ
cardioP↑, 2, cognitive↑, 2, hepatoP↑, 2, memory↑, 1, neuroP↑, 2, OS↑, 1,
Total Targets: 48
Scientific Paper Hit Count for: creat, creatinine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:75 Cells:% prod#:% Target#:1251 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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