necrosis Cancer Research Results
necrosis, necrosis: Click to Expand ⟱
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| Type: type of cell death |
Necrosis is a type of cell death that occurs when cells are damaged or injured, leading to the loss of cellular homeostasis and the eventual death of the cell. Necrosis is a non-programmed form of cell death, meaning that it is not a deliberate or controlled process, but rather a response to cellular damage or injury.
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Park, Parkinson's Disease (PD): Click to Expand ⟱
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, and is due to the degeneration of dopaminergic neurons. It is multifactorial, caused by genetic and environmental factors and currently has no definitive cure.
-CoQ10 deficiency was observed at a higher frequency in Parkinson's disease
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Scientific Papers found: Click to Expand⟱
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Review, |
Var, |
NA |
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Review, |
Stroke, |
NA |
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Review, |
Diabetic, |
NA |
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Review, |
Park, |
NA |
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*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2↓, *MDA↓,
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Review, |
AD, |
NA |
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Review, |
Park, |
NA |
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Review, |
Stroke, |
NA |
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*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *BBB?, *tau↓, *NF-kB↓, *IL1β↓, *TNF-α↓, *IL4↓, *MAPK↓, *memory↑, *cognitive↑, *Aβ↓, *ROS↓, *lipid-P↓, *GSH↑, *MDA↓, *SOD↑, *Catalase↑, *AChE↓, *BChE↓, *p‑ERK↓, *p‑JNK↓, *p‑p38↓, *GutMicro↑, *COX2↓, *iNOS↓, *TLR4↓, *neuroP↑, *Strength↑, *AMPK↑, *MMP↑, *necrosis↓, *NRF2↑, *HO-1↑,
Showing Research Papers: 1 to 2 of 2
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
Mitochondria & Bioenergetics ⓘ
MMP↓, 1,
Core Metabolism/Glycolysis ⓘ
ALAT↓, 1,
Cell Death ⓘ
Apoptosis↓, 1,
Cell Cycle & Senescence ⓘ
CDK4↓, 1, cycD1/CCND1↓, 1, TumCCA↑, 1,
Proliferation, Differentiation & Cell State ⓘ
ERK↓, 1, NOTCH↓, 1, PI3K↓, 1,
Migration ⓘ
MMP2↓, 1, MMP9↓, 1,
Immune & Inflammatory Signaling ⓘ
IL6↓, 1,
Clinical Biomarkers ⓘ
ALAT↓, 1, IL6↓, 1,
Functional Outcomes ⓘ
chemoP↑, 1,
Total Targets: 16
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 1, Catalase↑, 2, GPx↑, 1, GSH↑, 1, HO-1↑, 1, lipid-P↓, 1, MDA↓, 2, NRF2↑, 1, ROS↓, 3, SOD↑, 2,
Mitochondria & Bioenergetics ⓘ
MMP↑, 1,
Core Metabolism/Glycolysis ⓘ
AMPK↑, 1, LDH↓, 1,
Cell Death ⓘ
Apoptosis↓, 1, iNOS↓, 1, p‑JNK↓, 1, MAPK↓, 1, necrosis↓, 2, p‑p38↓, 1,
Proliferation, Differentiation & Cell State ⓘ
p‑ERK↓, 1, TRPM7↓, 1,
Migration ⓘ
AntiAg↑, 1,
Barriers & Transport ⓘ
BBB?, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 2, IL1β↓, 1, IL4↓, 1, Imm↑, 1, Inflam↓, 1, NF-kB↓, 2, TLR4↓, 1, TNF-α↓, 1,
Synaptic & Neurotransmission ⓘ
AChE↓, 1, BChE↓, 1, tau↓, 1,
Protein Aggregation ⓘ
Aβ↓, 1,
Clinical Biomarkers ⓘ
AST↓, 1, GutMicro↑, 1, LDH↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, AntiDiabetic↑, 1, cardioP↑, 1, cognitive↑, 1, hepatoP↑, 1, memory↑, 1, motorD↑, 1, neuroP↑, 3, Obesity↓, 1, Pain↓, 1, Strength↑, 1,
Infection & Microbiome ⓘ
Bacteria↓, 1,
Total Targets: 50
Scientific Paper Hit Count for: necrosis, necrosis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:75 Cells:% prod#:% Target#:781 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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