chemoP Cancer Research Results
chemoP, ChemoProtective: Click to Expand ⟱
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Protects normal cells against the effect of Chemo.
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Park, Parkinson's Disease (PD): Click to Expand ⟱
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, and is due to the degeneration of dopaminergic neurons. It is multifactorial, caused by genetic and environmental factors and currently has no definitive cure.
-CoQ10 deficiency was observed at a higher frequency in Parkinson's disease
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Scientific Papers found: Click to Expand⟱
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Review, |
AD, |
NA |
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Var, |
NA |
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Review, |
Park, |
NA |
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Review, |
Stroke, |
NA |
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*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2↓, p‑FAK↓,
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Review, |
Var, |
NA |
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Review, |
Stroke, |
NA |
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Diabetic, |
NA |
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Park, |
NA |
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*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2↓, *MDA↓,
Showing Research Papers: 1 to 2 of 2
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSH↓, 1, ROS↑, 2,
Mitochondria & Bioenergetics ⓘ
MMP↓, 1,
Core Metabolism/Glycolysis ⓘ
ALAT↓, 1,
Cell Death ⓘ
Apoptosis↓, 1, Bcl-2↓, 1, Casp12↑, 1, Casp3↑, 1, Casp8↑, 1, Casp9↑, 1, Cyt‑c↑, 1, Fas↑, 1, p38↑, 1,
DNA Damage & Repair ⓘ
CHK1↓, 1, P53↑, 1,
Cell Cycle & Senescence ⓘ
CDK4↓, 1, CycB/CCNB1↓, 1, cycD1/CCND1↓, 1, P21↑, 1, TumCCA↑, 2,
Proliferation, Differentiation & Cell State ⓘ
ERK↓, 1, NOTCH↓, 1, PI3K↓, 1, STAT3↓, 1,
Migration ⓘ
p‑FAK↓, 1, MMP2↓, 1, MMP9↓, 1, TumCMig↓, 1,
Angiogenesis & Vasculature ⓘ
Hif1a↓, 1, VEGF↓, 1, VEGFR2↓, 1,
Immune & Inflammatory Signaling ⓘ
IL6↓, 1, IL8↓, 1,
Clinical Biomarkers ⓘ
ALAT↓, 1, IL6↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, chemoP↑, 2,
Total Targets: 37
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 3, Catalase↑, 1, GPx↑, 1, GSH↑, 1, GSTs↑, 1, Keap1↓, 1, lipid-P↓, 1, MDA↓, 2, MPO↓, 1, NRF2↑, 1, ROS↓, 3, SOD↑, 2, TBARS↓, 1,
Core Metabolism/Glycolysis ⓘ
ALAT↓, 1, H2S↑, 1, LDH↓, 3,
Cell Death ⓘ
Akt↓, 1, iNOS↓, 1, necrosis↓, 1,
Transcription & Epigenetics ⓘ
other↑, 1,
Proliferation, Differentiation & Cell State ⓘ
PI3K↓, 1, TRPM7↓, 1,
Migration ⓘ
AntiAg↑, 1,
Angiogenesis & Vasculature ⓘ
NO↓, 1,
Barriers & Transport ⓘ
BBB↑, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 2, IL6↓, 1, Imm↑, 1, Inflam↓, 1, NF-kB↓, 2, PGE2↓, 1, TNF-α↓, 1,
Drug Metabolism & Resistance ⓘ
eff↑, 1, Half-Life↝, 1,
Clinical Biomarkers ⓘ
ALAT↓, 1, AST↓, 2, BP↓, 1, creat↓, 1, GutMicro↑, 1, IL6↓, 1, LDH↓, 3,
Functional Outcomes ⓘ
AntiCan↑, 1, AntiDiabetic↑, 1, cardioP↑, 2, cognitive↑, 1, hepatoP↑, 2, memory↑, 1, motorD↑, 1, neuroP↑, 3, Obesity↓, 1, Pain↓, 1,
Infection & Microbiome ⓘ
Bacteria↓, 1,
Total Targets: 52
Scientific Paper Hit Count for: chemoP, ChemoProtective
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:75 Cells:% prod#:% Target#:1171 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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