eff Cancer Research Results
eff, efficacy: Click to Expand ⟱
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Power to enhance an anti cancer effect
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Park, Parkinson's Disease (PD): Click to Expand ⟱
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, and is due to the degeneration of dopaminergic neurons. It is multifactorial, caused by genetic and environmental factors and currently has no definitive cure.
-CoQ10 deficiency was observed at a higher frequency in Parkinson's disease
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Scientific Papers found: Click to Expand⟱
| - |
Review, |
AD, |
NA |
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Review, |
Var, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
Stroke, |
NA |
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*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2↓, p‑FAK↓,
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Review, |
Var, |
NA |
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- |
Review, |
Stroke, |
NA |
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- |
Review, |
IBD, |
NA |
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- |
Review, |
Arthritis, |
NA |
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- |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
Stroke, |
NA |
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*neuroP↑, *memory↑, *Pain↓, *TRPV1↑, *Aβ↓, *tau↓, *cognitive↑, *Risk↓, *motorD↓, *ROS↓, *TNF-α↓, *IL1β↓, *eff↑, *Risk↓,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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*memory↑, *cognitive↑, *ROS↓, *Inflam↓, *motorD↑, *toxicity↓, *TRPV3↑, *other↓, *antiOx↑, *LDL↓, *COX2↓, *PPARα↑, *NO↓, *AChE↓, *eff↑, *SOD↑, *Catalase↑, *neuroP↑, *BioAv↝, *BBB↑, *BioAv↑,
| - |
Review, |
Var, |
NA |
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- |
Review, |
Diabetic, |
NA |
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- |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
Stroke, |
NA |
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*neuroP↑, *Inflam↓, *antiOx↑, *cardioP↑, *NRF2↑, *AMPK↑, *SOD↑, *Catalase↑, *GSH↑, *GPx↑, *ROS↓, *TNF-α↓, *IL6↓, *NF-kB↓, *COX2↓, *glucose↓, *TRPC1↓, *Ca+2↓, *HO-1↑, *NF-kB↓, *PPARα↝, *Hif1a↓, *JNK↓, *BP↓, *AntiDiabetic↑, *hepatoP↑, *TLR4↓, *NRF2↑, *Casp↓, *neuroP↑, *Aβ↓, *LDH↓, *MDA↓, *memory↑, *AChE↓, *eff↑, EMT↝, N-cadherin↓, E-cadherin↑, TumCCA↑, ROS↑, p‑P53↑, HO-1↑, NRF2↑, ChemoSen↑, mtDam↑, Casp3↑, Casp9↑, PARP↑, Bax:Bcl2↑, TumCG↓, cycD1/CCND1↓, cMyc↓, CDK2↓, mitResp↓, Glycolysis↓, Hif1a↓, PCNA↓, p‑GSK‐3β↓, VEGF↓, PI3K↓, Akt↓, mTOR↓, OS↑,
| - |
Review, |
Var, |
NA |
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- |
Review, |
Stroke, |
NA |
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- |
Review, |
Park, |
NA |
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*antiOx↑, *Inflam↓, *hepatoP↑, *neuroP↑, *BioAv↓, *cardioP↑, *lipidLev↓, *RenoP↑, *TNF-α↓, *IL2↓, *PI3K↓, *Akt↓, *ROS↓, *cognitive↑, eff↑, cycD1/CCND1↓, hTERT/TERT↓, VEGF↓, p‑STAT3↓, TumMeta↓, TumCP↓, eff↑, eff↑, IL1β↓, IL6↓, NF-kB↓, ROS↑, MMP↓, Cyt‑c↑, Apoptosis↑, ER Stress↑, Ca+2↑, TET1↑, Let-7↑, Twist↓, EMT↓, TumCCA↑, Casp3↑, Casp9↑, BAX↑, HK2↓, GlucoseCon↓, lactateProd↓, Glycolysis↓, SHP1↑, N-cadherin↓, E-cadherin↑, UPR↑, PERK↑, ATF4↑, eIF2α↑, RadioS↑, NOTCH1↑, NRF2↓, BioAv↑, eff↑,
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Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *eff↑, *LDL↓, *HDL↑, *eff↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
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Review, |
Nor, |
NA |
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- |
Review, |
Stroke, |
NA |
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- |
Review, |
Park, |
NA |
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*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
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in-vivo, |
ALS, |
NA |
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NA, |
Stroke, |
NA |
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- |
NA, |
AD, |
NA |
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- |
NA, |
Park, |
NA |
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*eff↑, *ROS↓, *GSH↑, *NRF2↑, *motorD↑, *OS↑, *neuroP↑, *BBB↑, *cognitive↑, *eff↑, *antiOx↑, *Cyt‑c↑, *PGC-1α↑,
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Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
MS, |
NA |
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- |
Review, |
Stroke, |
NA |
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*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↝, *BBB↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL33↓, *NF-kB↓, *BACE↓, *ROS↓, *SOD↑, *HO-1↑, *NRF2↑, *Casp3↓, *Casp9↑, *Bax:Bcl2↓, *UPR↑, *GRP78/BiP↑, *Aβ↓, *GSK‐3β↓, *tau↓, *CREB↑, *ATP↑, *cognitive↑, *BloodF↑, *BDNF↑, *TrkB↑, *memory↑, *PPARγ↑, *eff↑,
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in-vitro, |
Park, |
SK-N-SH |
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- |
in-vitro, |
AD, |
NA |
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*ROS↓, *neuroP↑, *MMP↑, *Catalase↑, *GSH↑, selectivity↑, *eff↑, *Cyt‑c↓,
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in-vitro, |
Stroke, |
1321N1 |
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- |
in-vitro, |
Park, |
NA |
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*VEGF↑, *eff↑, *neuroP↑, *other↑, *eff↑, *Inflam↓, *Hif1a∅,
| - |
Review, |
Stroke, |
NA |
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- |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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*eff↑, *BBB↑, *Dose↝, *neuroP↑, *cognitive↑, *toxicity∅,
| - |
Review, |
Stroke, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
AD, |
NA |
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*eff↑, *cognitive↑,
| - |
Review, |
Nor, |
NA |
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- |
NA, |
AD, |
NA |
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- |
NA, |
Diabetic, |
NA |
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- |
NA, |
Stroke, |
NA |
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- |
NA, |
LiverDam, |
NA |
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- |
NA, |
Park, |
NA |
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*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,
| - |
Review, |
Park, |
NA |
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- |
Review, |
AD, |
NA |
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*hepatoP↑, *Inflam↓, *neuroP↑, *antiOx↑, *angioG↑, *cardioP↑, *BioAv↑, *P450↓, *eff↑, *BioAv↑, E-cadherin↓, ER(estro)↓, MMP2↓, MMP9↓, VEGF↓, cMyc↓, BAX↑, P53↑, TumCG↓, OS↑, *cognitive↑, *GSK‐3β↓, *GSH↑, *Casp3↓, *Casp9↓, *Cyt‑c↓, *lipid-P↓, *motorD↑, *AChE↓, *memory↑, *cardioP↑, *ROS↓, *PPARγ↑, *ALAT↓, *AST↓, *ALP↓, *AMPK↑, *5HT↑, *SIRT1↑, *eff↑,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
Stroke, |
NA |
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*Inflam↓, *neuroP↑, *cognitive↑, *Choline↑, *IL1β↓, *IL6↓, *TNF-α↓, *Ach↑, *eff↑, *eff↑, *BioEnh↑, other↑,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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*neuroP↑, *NRF2↑, *PONs↑, *antiOx↑, *Inflam↓, *SIRT1↑, *eff↑, *ROS↓, *cognitive↑, *eff↑, *lipid-P↓, *GSH↑, *GPx↑, *SOD↑, *NRF2↑,
| - |
Review, |
Var, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
AD, |
NA |
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JAK↓, STAT↓, Inflam↓, NO↓, COX2↓, CRP↓, selectivity↑, *neuroP↑, STAT3↓, cycD1/CCND1↓, MMP2↓, STAT4↓, JAK2↓, TumCP↓, Diff↓, *eff↑, *IL6↓, *TNF-α↓, *IL1β↓, *Aβ↓,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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*OS↑, *memory↑, *cognitive↑, *memory↑, *Aβ↓, *eff↑, *HSF1↑, *HSP70/HSPA5↑,
*eff↑, *PKM2↓, *motorD↑, *lactateProd↓,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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*neuroP↑, *hepatoP↑, *cardioP↑, *Inflam↓, *antiOx↑, ChemoSen↑, eff↑, eff↑, TumCP↓, TumCCA↑, angioG↓, cycA1/CCNA1↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
Stroke, |
NA |
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*MitoP↑, *Inflam↓, *antiOx↑, *Risk↓, *Aβ↓, *p‑tau↓, *p62↓, *PARK2↑, *MMP↑, *ROS↓, *Strength↑, *CRP↓, *IL1β↓, *IL6↓, *TNF-α↓, *AMPK↑, *NF-kB↓, *MAPK↓, *p62↑, *NRF2↑, *SOD↑, *Catalase↑, *HO-1↑, *Ferroptosis↓, *lipid-P↓, *Cartilage↑, *PI3K↓, *Akt↓, *mTOR↓, *Apoptosis↓, *neuroP↑, *Bcl-2↓, *BAX↑, *Casp3↑, *ATP↑, *eff↑, *motorD↑, *NLRP3↓, *radioP↑, *BBB↑,
| - |
Review, |
Park, |
NA |
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- |
Review, |
AD, |
NA |
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*Inflam↓, *antiOx↓, *neuroP↑, *p‑tau↓, *Aβ↓, *eff↑, *BioAv↓, *BioAv↑, *GSH↑, *SOD↑, *lipid-P↓, *Catalase↑, *GSR↑, *GPx↑, *ROS↓, *NRF2↑, *GutMicro↑, *Risk↓, *BBB↓, *NLRP3↓, *MAOA↓,
Showing Research Papers: 1 to 24 of 24
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 24
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSH↓, 1, GSTs↑, 1, HO-1↑, 2, NRF2↓, 1, NRF2↑, 2, ROS↑, 3,
Mitochondria & Bioenergetics ⓘ
mitResp↓, 1, MMP↓, 1, mtDam↑, 1,
Core Metabolism/Glycolysis ⓘ
cMyc↓, 2, GlucoseCon↓, 1, Glycolysis↓, 2, HK2↓, 1, lactateProd↓, 1,
Cell Death ⓘ
Akt↓, 1, Apoptosis↑, 1, BAX↑, 2, Bax:Bcl2↑, 1, Bcl-2↓, 1, Casp12↑, 1, Casp3↑, 3, Casp8↑, 1, Casp9↑, 3, Cyt‑c↑, 2, Fas↑, 1, hTERT/TERT↓, 1, p38↑, 1,
Transcription & Epigenetics ⓘ
other↑, 1,
Protein Folding & ER Stress ⓘ
eIF2α↑, 1, ER Stress↑, 1, PERK↑, 1, UPR↑, 1,
DNA Damage & Repair ⓘ
CHK1↓, 1, P53↑, 2, p‑P53↑, 1, PARP↑, 1, PCNA↓, 1,
Cell Cycle & Senescence ⓘ
CDK2↓, 2, cycA1/CCNA1↓, 1, CycB/CCNB1↓, 1, cycD1/CCND1↓, 4, cycE/CCNE↓, 1, P21↑, 1, TumCCA↑, 4,
Proliferation, Differentiation & Cell State ⓘ
Diff↓, 1, EMT↓, 1, EMT↝, 1, p‑GSK‐3β↓, 1, Let-7↑, 1, mTOR↓, 1, NOTCH1↑, 1, PI3K↓, 1, SHP1↑, 1, STAT↓, 1, STAT3↓, 2, p‑STAT3↓, 1, STAT4↓, 1, TumCG↓, 2,
Migration ⓘ
Ca+2↑, 1, E-cadherin↓, 1, E-cadherin↑, 2, p‑FAK↓, 1, MMP2↓, 2, MMP9↓, 1, N-cadherin↓, 2, TET1↑, 1, TumCMig↓, 1, TumCP↓, 3, TumMeta↓, 1, Twist↓, 1,
Angiogenesis & Vasculature ⓘ
angioG↓, 1, ATF4↑, 1, Hif1a↓, 2, NO↓, 1, VEGF↓, 4, VEGFR2↓, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, CRP↓, 1, IL1β↓, 2, IL6↓, 1, IL8↓, 1, Inflam↓, 2, JAK↓, 1, JAK2↓, 1, NF-kB↓, 2,
Hormonal & Nuclear Receptors ⓘ
ER(estro)↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↑, 1, BioAv↝, 1, ChemoSen↑, 3, eff↑, 6, RadioS↑, 1, selectivity↑, 2,
Clinical Biomarkers ⓘ
CRP↓, 1, hTERT/TERT↓, 1, IL6↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, cardioP↑, 1, chemoP↑, 1, cognitive↑, 2, OS↑, 2,
Total Targets: 100
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↓, 1, antiOx↑, 13, Catalase↑, 6, Ferroptosis↓, 1, GPx↑, 3, GSH↑, 9, GSR↑, 1, GSTs↑, 1, HDL↑, 1, HO-1↑, 3, Keap1↓, 1, lipid-P↓, 7, MDA↓, 2, MPO↓, 2, NRF2↑, 9, PARK2↑, 1, ROS?, 1, ROS↓, 17, SOD↑, 9, TBARS↓, 1,
Mitochondria & Bioenergetics ⓘ
ATP↑, 2, MMP↑, 3, mtDam↓, 1, PGC-1α↑, 1,
Core Metabolism/Glycolysis ⓘ
12LOX↓, 1, ALAT↓, 2, AMPK↑, 3, CREB↑, 1, glucose↓, 1, H2S↑, 1, lactateProd↓, 1, LDH↓, 3, LDL↓, 2, lipidLev↓, 1, PKM2↓, 1, PONs↑, 1, PPARα↑, 1, PPARα↝, 1, PPARγ↑, 2, SIRT1↑, 3,
Cell Death ⓘ
Akt↓, 3, Apoptosis↓, 1, BAX↑, 1, Bax:Bcl2↓, 1, Bcl-2↓, 1, Casp↓, 1, Casp3↓, 2, Casp3↑, 1, Casp9↓, 1, Casp9↑, 1, Cyt‑c↓, 2, Cyt‑c↑, 1, Ferroptosis↓, 1, iNOS↓, 1, JNK↓, 1, MAPK↓, 1, TRPV1↑, 1,
Kinase & Signal Transduction ⓘ
TRPV3↑, 1,
Transcription & Epigenetics ⓘ
Ach↑, 1, other↓, 1, other↑, 3, other↝, 1, other∅, 1,
Protein Folding & ER Stress ⓘ
GRP78/BiP↑, 1, HSF1↑, 1, HSP70/HSPA5↑, 1, UPR↑, 1,
Autophagy & Lysosomes ⓘ
MitoP↑, 1, p62↓, 1, p62↑, 1,
DNA Damage & Repair ⓘ
DNAdam↓, 1,
Proliferation, Differentiation & Cell State ⓘ
Choline↑, 1, GSK‐3β↓, 2, IGF-1↑, 1, IGFBP1↑, 1, mTOR↓, 1, PI3K↓, 3, STAT3↓, 1,
Migration ⓘ
Ca+2↓, 1, Cartilage↑, 1, MMP2↓, 1, MMP9↓, 1, TRPC1↓, 1,
Angiogenesis & Vasculature ⓘ
angioG↑, 1, Hif1a↓, 1, Hif1a∅, 1, NO↓, 2, NO↑, 1, VEGF↑, 1,
Barriers & Transport ⓘ
BBB↓, 1, BBB↑, 8,
Immune & Inflammatory Signaling ⓘ
COX2↓, 5, CRP↓, 1, IL10↑, 1, IL1β↓, 6, IL2↓, 1, IL33↓, 1, IL6↓, 8, IL6↑, 1, IL8↓, 1, Inflam↓, 14, NF-kB↓, 6, PGE2↓, 2, TLR4↓, 1, TNF-α↓, 11,
Synaptic & Neurotransmission ⓘ
5HT↑, 1, AChE↓, 3, BDNF↑, 3, MAOA↓, 1, tau↓, 2, p‑tau↓, 2, TrkB↑, 1,
Protein Aggregation ⓘ
Aβ↓, 8, BACE↓, 1, NLRP3↓, 2, β-Amyloid↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↓, 2, BioAv↑, 6, BioAv↝, 5, BioEnh↑, 1, Dose↝, 4, eff↑, 30, Half-Life↝, 1, P450↓, 1,
Clinical Biomarkers ⓘ
ALAT↓, 2, ALP↓, 1, AST↓, 2, BG↓, 1, BloodF↑, 1, BP↓, 3, creat↓, 2, CRP↓, 1, GutMicro↑, 3, IL6↓, 8, IL6↑, 1, LDH↓, 3,
Functional Outcomes ⓘ
AntiAge↑, 1, AntiDiabetic↑, 1, cardioP↑, 8, cognitive↑, 13, hepatoP↑, 7, memory↑, 8, motorD↓, 1, motorD↑, 5, neuroP↑, 22, OS↑, 3, Pain↓, 1, QoL↑, 1, radioP↑, 1, RenoP↑, 2, Risk↓, 4, Strength↑, 1, toxicity↓, 1, toxicity↑, 1, toxicity∅, 1,
Total Targets: 155
Scientific Paper Hit Count for: eff, efficacy
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:75 Cells:% prod#:% Target#:961 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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