other Cancer Research Results

other, other: Click to Expand ⟱
Source:
Type:
custom


Park, Parkinson's Disease (PD): Click to Expand ⟱
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, and is due to the degeneration of dopaminergic neurons. It is multifactorial, caused by genetic and environmental factors and currently has no definitive cure.
-CoQ10 deficiency was observed at a higher frequency in Parkinson's disease


Scientific Papers found: Click to Expand⟱
5297- 5-HTP,    Targeting 5-HT Is a Potential Therapeutic Strategy for Neurodegenerative Diseases
- in-vivo, AD, NA - in-vivo, Park, NA
*other↝, *cognitive↑, *memory↑, *Ach↑,
5768- CAPE,    Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*antiOx↑, *Inflam↑, *AntiCan↑, *NRF2↑, *GSK‐3β↑, *Akt↑, *PI3K↑, *ROS↓, *SOD↑, *GSH↑, *MDA↓, *tau↓, *neuroP↑, *memory↑, *AChE↓, *other↝, *lipid-P↓,
5943- Cela,    Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases
- Review, Arthritis, NA - Review, IBD, NA - Review, AD, NA - Review, Park, NA
*other↝, *other↝, *CRP↓, *eff↝, *other↑, *CXCR4↓, *IL1β↓, *IL6↓, *IL17↓, *IL18↓, *TNF-α↓, *MMP9↓, *PGE2↓, *COX1↓, *COX2↓, *PI3K↓, *Akt↓, *other↑, TumCCA↑, Apoptosis↑, ROS↑, JNK↑, TumAuto↑, Hif1a↓, BNIP3↝, HSP90↓, Fas↑, FasL↑, ETC↓, VEGF↓, angioG↓, RadioS↑, *neuroP↑, *HSP70/HSPA5↑, *ROS↓, *MMP↑, *Cyt‑c↓, *Casp3↓, *Casp9↓, *MAPK↓, *Dose⇅, *HSPs↑, BioAv↓, Dose↝,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *eff↑, *LDL↓, *HDL↑, *eff↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
4332- Cyste,    Cystamine metabolism and brain transport properties: clinical implications for neurodegenerative diseases
- in-vivo, Park, NA - in-vivo, HD, NA
*neuroP↑, *other↝, *other↝,
4324- VitB5,    Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson’s Disease Dementia
- Study, AD, NA - Study, Park, NA
*Risk↓, *other↝, *other↝, *Ach↑, *Aβ↑, *other?,
4325- VitB5,    Localized Pantothenic Acid (Vitamin B5) Reductions Present Throughout the Dementia with Lewy Bodies Brain
- Study, AD, NA - Study, Park, NA
*Risk↑, *Dose↝, *Dose↓, *other↝,

Showing Research Papers: 1 to 7 of 7

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

ROS↑, 1,  

Mitochondria & Bioenergetics

ETC↓, 1,  

Cell Death

Apoptosis↑, 1,   Fas↑, 1,   FasL↑, 1,   JNK↑, 1,  

Protein Folding & ER Stress

HSP90↓, 1,  

Autophagy & Lysosomes

BNIP3↝, 1,   TumAuto↑, 1,  

Cell Cycle & Senescence

TumCCA↑, 1,  

Angiogenesis & Vasculature

angioG↓, 1,   Hif1a↓, 1,   VEGF↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   Dose↝, 1,   RadioS↑, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 2,   GSH↑, 1,   HDL↑, 1,   lipid-P↓, 2,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 3,   SOD↑, 1,  

Mitochondria & Bioenergetics

MMP↑, 1,  

Core Metabolism/Glycolysis

LDL↓, 1,  

Cell Death

Akt↓, 1,   Akt↑, 1,   Casp3↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   MAPK↓, 1,  

Transcription & Epigenetics

Ach↑, 2,   other?, 1,   other↑, 3,   other↝, 10,   other∅, 1,  

Protein Folding & ER Stress

HSP70/HSPA5↑, 1,   HSPs↑, 1,  

Proliferation, Differentiation & Cell State

GSK‐3β↑, 1,   IGF-1↑, 1,   IGFBP1↑, 1,   PI3K↓, 1,   PI3K↑, 1,  

Migration

MMP9↓, 1,  

Immune & Inflammatory Signaling

COX1↓, 1,   COX2↓, 1,   CRP↓, 1,   CXCR4↓, 1,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 1,   IL6↓, 2,   Inflam↓, 1,   Inflam↑, 1,   PGE2↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission

AChE↓, 1,   tau↓, 1,  

Protein Aggregation

Aβ↑, 1,  

Drug Metabolism & Resistance

Dose↓, 1,   Dose⇅, 1,   Dose↝, 2,   eff↑, 2,   eff↝, 1,  

Clinical Biomarkers

BP↓, 1,   CRP↓, 1,   IL6↓, 2,  

Functional Outcomes

AntiAge↑, 1,   AntiCan↑, 1,   cardioP↑, 1,   cognitive↑, 1,   memory↑, 2,   neuroP↑, 4,   QoL↑, 1,   RenoP↑, 1,   Risk↓, 1,   Risk↑, 1,  
Total Targets: 62

Scientific Paper Hit Count for: other, other
2 Vitamin B5,Pantothenic Acid
1 5-Hydroxytryptophan
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Celastrol
1 Coenzyme Q10
1 Selenium
1 Cysteamine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:75  Cells:%  prod#:%  Target#:767  State#:%  Dir#:4
wNotes=0 sortOrder:rid,rpid

 

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