Database Query Results : , ,

fibroS, Fibrosarcoma: Click to Expand ⟱
Fibrosarcoma is a malignant tumor that arises from fibroblasts, the connective tissue cells responsible for producing collagen and other components of the extracellular matrix.
Scientific Papers found: Click to Expand⟱
2204- erastin,    Regulation of ferroptotic cancer cell death by GPX4
- in-vitro, fibroS, HT1080
GSH↓, Ferroptosis↑, ROS↑, GPx↓, GPx4↓, lipid-P↑, eff↓, eff↑,
4363- SNP,    Immunomodulatory properties of silver nanoparticles contribute to anticancer strategy for murine fibrosarcoma
- in-vivo, fibroS, NA
TumVol↓, TNF-α↓, IL6↓, IL1β↓, *toxicity↝, TumCG↓, selectivity↑, selectivity↑, Weight↑, ROS↑, NO↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx↓, 1,   GPx4↓, 1,   GSH↓, 1,   lipid-P↑, 1,   ROS↑, 2,  

Cell Death ⓘ

Ferroptosis↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  

Angiogenesis & Vasculature ⓘ

NO↑, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 1,   IL6↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↓, 1,   eff↑, 1,   selectivity↑, 2,  

Clinical Biomarkers ⓘ

IL6↓, 1,  

Functional Outcomes ⓘ

TumVol↓, 1,   Weight↑, 1,  
Total Targets: 18

Pathway results for Effect on Normal Cells:


Functional Outcomes ⓘ

toxicity↝, 1,  
Total Targets: 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:78  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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