ATP Cancer Research Results

ATP, Adenosine triphosphate: Click to Expand ⟱
Source:
Type:
Adenosine triphosphate (ATP) is the source of energy for use and storage at the cellular level.
Cellular ATP levels are critical for cell survival, and several reports have shown that reductions in cellular ATP levels can lead to apoptosis and other types of cell death in cancer cells, depending on the level of depletion.
Adenosine triphosphate (ATP) is one of the main biochemical components of the tumor microenvironment (TME), where it can promote tumor progression or tumor suppression depending on its concentration and on the specific ecto-nucleotidases and receptors expressed by immune and cancer cells.

Cancer cells, unlike normal cells, derive as much as 60% of their ATP from glycolysis via the “Warburg effect”, and the remaining 40% is derived from mitochondrial oxidative phosphorylation.


asthmatic, Asthmatic: Click to Expand ⟱
Asthmatic


Scientific Papers found: Click to Expand⟱
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,
2512- H2,    Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch
- in-vivo, asthmatic, NA
selectivity↑, lactateProd↓, ATP↑, HK2↓, PFK↓, Hif1a↓, PGC-1α↑, Glycolysis↓, OXPHOS↑, Dose↝,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

OXPHOS↑, 1,  

Mitochondria & Bioenergetics

ATP↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis

Glycolysis↓, 1,   HK2↓, 1,   lactateProd↓, 1,   PFK↓, 1,  

Angiogenesis & Vasculature

Hif1a↓, 1,  

Immune & Inflammatory Signaling

PGE2↓, 1,  

Drug Metabolism & Resistance

Dose↝, 1,   selectivity↑, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   NRF2↑, 1,  

Mitochondria & Bioenergetics

ATP↑, 1,  

Kinase & Signal Transduction

TRPV3↑, 1,  

Transcription & Epigenetics

other↝, 1,  

Migration

5LO↓, 1,   AntiAg↑, 1,   Ca+2↑, 1,  

Barriers & Transport

GastroP↑, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   CRP↓, 1,   Inflam↓, 1,  

Synaptic & Neurotransmission

AChE↓, 1,   BChE↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 1,   eff↑, 1,  

Clinical Biomarkers

CRP↓, 1,  

Functional Outcomes

cardioP↑, 1,   chemoPv↑, 1,   cognitive↑, 1,   hepatoP↑, 1,   neuroP↑, 1,   Pain↓, 1,   toxicity↓, 1,  

Infection & Microbiome

Diar↓, 1,  
Total Targets: 25

Scientific Paper Hit Count for: ATP, Adenosine triphosphate
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:80  Cells:%  prod#:%  Target#:21  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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