Database Query Results : , ,

BPH, Benign Prostatic Hyperplasia: Click to Expand ⟱
Benign Prostatic Hyperplasia (BPH) is a noncancerous enlargement of the prostate gland that commonly occurs in older men.
- Increased DHT levels in prostatic tissue are associated with hyperplasia.
- An imbalance in IGF signaling might contribute to abnormal growth.
- Targeted therapies (such as 5α-reductase inhibitors and α-blockers).
Scientific Papers found: Click to Expand⟱
4622- Bor,    Boron Level in the Prostate of the Normal Human: A Systematic Review
- Review, BPH, NA
Dose↝,
4621- Bor,    Boron
- Review, BPH, NA
*other↝, Risk↑, *Dose↑,
761- Bor,    Prevalence of Prostate Cancer in High Boron-Exposed Population: A Community-Based Study
- Study, BPH, NA
other↓,
3473- MF,    Therapeutic use of pulsed electromagnetic field therapy reduces prostate volume and lower urinary tract symptoms in benign prostatic hyperplasia
- Human, BPH, NA
*Inflam↓, *Dose↝, *other?,
3328- SIL,    Modulatory effect of silymarin on inflammatory mediators in experimentally induced benign prostatic hyperplasia: emphasis on PTEN, HIF-1α, and NF-κB
- in-vivo, BPH, NA
*NF-kB↓, *Hif1a↓, *PTEN↑, *Weight↓, *NO↓, *IL6↓, *IL8↓, *COX2↓, *iNOS↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics ⓘ

other↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 1,  

Functional Outcomes ⓘ

Risk↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Cell Death ⓘ

iNOS↓, 1,  

Transcription & Epigenetics ⓘ

other?, 1,   other↝, 1,  

Proliferation, Differentiation & Cell State ⓘ

PTEN↑, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 1,   NO↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IL6↓, 1,   IL8↓, 1,   Inflam↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↑, 1,   Dose↝, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  

Functional Outcomes ⓘ

Weight↓, 1,  
Total Targets: 15

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:86  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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