Licorice / TumCMig Cancer Research Results

LE, Licorice: Click to Expand ⟱

Features:

Glycyrrhizic acid (GA) is a significant constituent of licorice root.
Glycyrrhizin, the main active component obtained from licorice roots, has many pharmacological and biological functions such as protecting liver cells, anti-inflammation, anti-virus, immunomodulation, has been widely applied in the treatment of clinically related hepatic diseases (Dastagir & Rizvi, 2016). Glycyrrhizin is a natural inhibitor of HMGB1

TumCMig, Tumor cell migration: Click to Expand ⟱

Source:

Type:

Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.

Scientific Papers found: Click to Expand⟱

1266-

LE,

Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells

in-vitro,

Lung,

A549

in-vitro,

Nor,

BEAS-2B

HMGB1↓, EMT↓, TumCMig↓, p‑SMAD2↓, p‑SMAD3↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,

Migration ⓘ

p‑SMAD2↓, 1, p‑SMAD3↓, 1, TumCMig↓, 1,

Immune & Inflammatory Signaling ⓘ

HMGB1↓, 1,
Total Targets: 5

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: TumCMig, Tumor cell migration

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells