Physalin F & B / GLI2 Cancer Research Results

PFB, Physalin F & B: Click to Expand ⟱

Features: Anti-inflammatory, immunomodulatory

From Physalis minima

GLI2, GLI2: Click to Expand ⟱

Source:

Type:

GLI1, GLI2, and GLI3 are key downstream effectors of the Hh signaling pathway, acting as nuclear transcription factors that bind to promoters to regulate target gene expression. Highly expressed genes in human gliomas.

Scientific Papers found: Click to Expand⟱

34-

PFB,

Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription

in-vitro,

PC,

PANC1

HH↓, Gli1↓, GLI2↓, PTCH1↓, Bcl-2↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

Bcl-2↓, 1,

Proliferation, Differentiation & Cell State ⓘ

Gli1↓, 1, HH↓, 1, PTCH1↓, 1,

Migration ⓘ

GLI2↓, 1,
Total Targets: 5

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: GLI2, GLI2

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells