Thymol-Thymus vulgaris / LDL Cancer Research Results
TV, Thymol-Thymus vulgaris: Click to Expand ⟱
LDL, LDL-cholesterol: Click to Expand ⟱
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The relationship between LDL (low-density lipoprotein) cholesterol and cancer is a complex and evolving area of research. LDL cholesterol is often referred to as "bad" cholesterol because high levels are associated with an increased risk of cardiovascular diseases.
Protumorigenic: High levels of LDL cholesterol can promote tumor growth by providing lipids that are essential for cell membrane synthesis and energy production. Additionally, LDL can influence inflammation and angiogenesis, further supporting tumor development.
Antitumorigenic: Some studies suggest that lowering LDL cholesterol through lifestyle changes or medications (like statins) may have a protective effect against certain cancers, although the evidence is not uniform across all cancer types.
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Scientific Papers found: Click to Expand⟱
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Review, |
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Diabetic, |
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Obesity, |
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AD, |
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Arthritis, |
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*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
H2O2↑, 1, lipid-P↑, 1, i-ROS↑, 1,
Metal & Cofactor Biology ⓘ
IronCh↑, 1,
Mitochondria & Bioenergetics ⓘ
AIF↑, 1, MMP↓, 1,
Cell Death ⓘ
APAF1↑, 1, Apoptosis↑, 1, BAX↑, 2, Bcl-2↓, 1, Casp3↑, 1, Casp8↑, 1, Casp9↑, 1, Cyt‑c↑, 1,
DNA Damage & Repair ⓘ
DNAdam↑, 2, cl‑PARP↑, 1,
Cell Cycle & Senescence ⓘ
TumCCA↑, 1,
Proliferation, Differentiation & Cell State ⓘ
ERK↓, 1,
Migration ⓘ
Ca+2↑, 2, MMP2↓, 1, MMP9↓, 1, PKCδ↓, 1, TumCMig↓, 1, TumCP↓, 1,
Angiogenesis & Vasculature ⓘ
angioG↓, 1,
Drug Metabolism & Resistance ⓘ
ChemoSen↑, 1,
Functional Outcomes ⓘ
AntiTum↑, 1, chemoP↑, 1, hepatoP↑, 1, radioP↑, 1, RenoP↑, 1,
Total Targets: 31
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 1, Catalase↑, 1, GPx↑, 2, GSH↑, 1, GSTs↑, 1, H2O2↓, 1, HDL↑, 1, MDA↓, 1, NADH↓, 1, RNS↓, 1, ROS↓, 1, SOD↑, 2,
Core Metabolism/Glycolysis ⓘ
LDL↓, 1,
Transcription & Epigenetics ⓘ
other↓, 1, other↑, 1,
Migration ⓘ
AntiAg↑, 1,
Angiogenesis & Vasculature ⓘ
NO↓, 1,
Barriers & Transport ⓘ
GastroP↑, 1,
Immune & Inflammatory Signaling ⓘ
COX1↓, 1, COX2↓, 1, Imm↑, 1, Inflam↓, 1,
Synaptic & Neurotransmission ⓘ
AChE↓, 1, BChE↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↑, 2, BioAv↝, 1, eff↑, 1, Half-Life↝, 1,
Clinical Biomarkers ⓘ
BP↓, 1, NOS2↓, 1,
Functional Outcomes ⓘ
AntiDiabetic↑, 1, cardioP↑, 1, cognitive↑, 1, Obesity↓, 1,
Infection & Microbiome ⓘ
Bacteria↓, 1,
Total Targets: 35
Scientific Paper Hit Count for: LDL, LDL-cholesterol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:161 Target#:71 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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