methylseleninic acid / NF-kB Cancer Research Results
MeSA, methylseleninic acid: Click to Expand ⟱
| Features: |
Methylseleninic acid, a widespread selenium-containing compound of organic nature.
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NF-kB, Nuclear factor kappa B: Click to Expand ⟱
| Source: HalifaxProj(inhibit) |
| Type: |
NF-kB signaling
Nuclear factor kappa B (NF-κB) is a transcription factor that plays a crucial role in regulating immune response, inflammation, cell proliferation, and survival.
NF-κB is often found to be constitutively active in many types of cancer cells. This persistent activation can promote tumorigenesis by enhancing cell survival, proliferation, and metastasis.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
BC, |
MDA-MB-231 |
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in-vitro, |
Pca, |
DU145 |
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Mcl-1↑, Mcl-1↓, MPT↑, AIF↑, chemoPv↑, Apoptosis↑, ROS↑, FAK↓, STAT3↓, NF-kB↓,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
Mitochondria & Bioenergetics ⓘ
AIF↑, 1, MPT↑, 1,
Cell Death ⓘ
Apoptosis↑, 1, Mcl-1↓, 1, Mcl-1↑, 1,
Proliferation, Differentiation & Cell State ⓘ
STAT3↓, 1,
Migration ⓘ
FAK↓, 1,
Immune & Inflammatory Signaling ⓘ
NF-kB↓, 1,
Functional Outcomes ⓘ
chemoPv↑, 1,
Total Targets: 10
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: NF-kB, Nuclear factor kappa B
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:190 Target#:214 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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