Radiotherapy/Radiation / tumCV Cancer Research Results

Rad, Radiotherapy/Radiation: Click to Expand ⟱
Features:
Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.

Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.
tumCV, Cell Viability: Click to Expand ⟱
Source:
Type:
Cell Viability
Scientific Papers found: Click to Expand⟱
4822- ASTX,  Rad,    Astaxanthin Synergizes with Ionizing Radiation (IR) in Oral Squamous Cell Carcinoma (OSCC)
tumCV↓, selectivity↑, RadioS↑, GPx4↓, Ferroptosis↑,
2715- BBR,  Rad,    Berberine Can Amplify Cytotoxic Effect of Radiotherapy by Targeting Cancer Stem Cells
- in-vitro, BC, MCF-7
tumCV↓, OCT4↓, SOX2↓, RadioS↑, CSCs↓,
5754- CAPE,  Rad,    The radiosensitizing effect of Caffeic Acid Phenethyl Ester in breast cancer is dependent on p53 status
- in-vivo, BC, MDA-MB-231
tumCV↓, eff⇅, RadioS↑, OS↑,
1311- NarG,  Rad,    Naringenin sensitizes lung cancer NCI-H23 cells to radiation by downregulation of akt expression and metastasis while promoting apoptosis
- in-vitro, Lung, H23
tumCV↓, ROS↑, Casp3↑, p‑Akt↓, Akt↓, MMP2↓, P21↓,
4887- ZER,  Rad,  Cisplatin,    Zerumbone acts as a radiosensitizer in head and neck squamous cell carcinoma
- in-vitro, HNSCC, CAL27
Apoptosis↑, ChemoSen↑, RadioS↑, tumCV↓,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx4↓, 1,   ROS↑, 1,  

Cell Death ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↑, 1,   Casp3↑, 1,   Ferroptosis↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 5,  

Cell Cycle & Senescence ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,   OCT4↓, 1,   SOX2↓, 1,  

Migration ⓘ

MMP2↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,   eff⇅, 1,   RadioS↑, 4,   selectivity↑, 1,  

Functional Outcomes ⓘ

OS↑, 1,  
Total Targets: 19

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: tumCV, Cell Viability
5 Radiotherapy/Radiation
1 Astaxanthin
1 Berberine
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Naringin
1 Zerumbone
1 Cisplatin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:201  Target#:897  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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