eicosapentaenoic acid / NF-kB Cancer Research Results

EPA, eicosapentaenoic acid: Click to Expand ⟱
Features:
Eicosapentaenoic Acid (EPA)
 – An omega-3 polyunsaturated fatty acid (PUFA) primarily found in marine sources such as fatty fish and algae.
 – EPA is involved in the synthesis of eicosanoids, which are signaling molecules that modulate inflammatory processes.
NF-kB, Nuclear factor kappa B: Click to Expand ⟱
Source: HalifaxProj(inhibit)
Type:
NF-kB signaling
Nuclear factor kappa B (NF-κB) is a transcription factor that plays a crucial role in regulating immune response, inflammation, cell proliferation, and survival.
NF-κB is often found to be constitutively active in many types of cancer cells. This persistent activation can promote tumorigenesis by enhancing cell survival, proliferation, and metastasis.
Scientific Papers found: Click to Expand⟱
1085- DHA,  EPA,    DHA and EPA Down-regulate COX-2 Expression through Suppression of NF-kappaB Activity in LPS-treated Human Umbilical Vein Endothelial Cells
- in-vitro, Nor, HUVECs
*COX2↓, *NF-kB↓, *PGE2↓, *IL6↓, *NF-kB↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IL6↓, 1,   NF-kB↓, 1,   NF-kB↑, 1,   PGE2↓, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  
Total Targets: 6

Scientific Paper Hit Count for: NF-kB, Nuclear factor kappa B
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:259  Target#:214  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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