diet Ketogenic / cachexia Cancer Research Results

dietKeto, diet Ketogenic: Click to Expand ⟱
Features:
The ketogenic diet is a high-fat, moderate-protein, and very low-carbohydrate diet. The drastic reduction in carbohydrate intake aims to shift the body’s metabolism from relying primarily on glucose (sugar) for energy to using ketone bodies produced from fat metabolism.
Many cancer cells predominantly rely on glucose for energy—a phenomenon known as the Warburg effect. By reducing carbohydrate intake, the KD lowers blood glucose levels, which theoretically could "starve" cancer cells of their preferred energy source.
-Lowering carbohydrate intake reduces insulin levels, which may indirectly decrease insulin-like growth factor (IGF) signaling—a pathway that can promote tumor growth in some cancers.
- MCT oil is rapidly metabolized in the liver to produce ketone bodies, making it a common component of ketogenic diets.
cachexia, cachexia: Click to Expand ⟱
Source:
Type:
Cachexia is a complex metabolic syndrome characterized by severe body weight, muscle, and fat loss that cannot be fully reversed by conventional nutritional support.
It is commonly associated with advanced cancers, including pancreatic, lung, gastrointestinal, and head and neck cancers.

Cachexia can lead to significant fatigue, decreased muscle strength, and overall physical debilitation, severely affecting a patient’s quality of life and functional status.
Scientific Papers found: Click to Expand⟱
1810- dietKeto,  Oxy,    The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
- in-vivo, Var, NA
BG↓, TumCG↓, OS↑, eff↑, Dose∅, KeyT↑, eff↑, cachexia↓, ChemoSen↑, *ROS↓, ROS↑, lipid-P↑, selectivity↑, toxicity∅,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

lipid-P↑, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis ⓘ

KeyT↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,   Dose∅, 1,   eff↑, 2,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

BG↓, 1,  

Functional Outcomes ⓘ

cachexia↓, 1,   OS↑, 1,   toxicity∅, 1,  
Total Targets: 12

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

ROS↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: cachexia, cachexia
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:283  Target#:1016  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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