Methyl Jasmonate / eff Cancer Research Results

MeJa, Methyl Jasmonate: Click to Expand ⟱

Features:

Methyl jasmonate (MeJa) is a well-known plant stress hormone.
Pathways:
-Causes mitochondrial dysfunction by inducing the release of cytochrome c, which leads to caspase activation.
- ↓ glycolysis via hexokinase-VDAC disruption
- ↑ ROS in cancer cells
-MJ can lead to cell cycle arrest, thereby inhibiting the proliferation of cancer cells

eff, efficacy: Click to Expand ⟱

Source:

Type:

Power to enhance an anti cancer effect

Scientific Papers found: Click to Expand⟱

1899-

MeJa,

Methyl jasmonate induces production of reactive oxygen species and alterations in mitochondrial dynamics that precede photosynthetic dysfunction and subsequent cell death

in-vitro,

NA,

100 mM

Plants

ROS↑, MMP↓, eff↓, H2O2?,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

H2O2?, 1, ROS↑, 1,

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,

Drug Metabolism & Resistance ⓘ

eff↓, 1,
Total Targets: 4

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: eff, efficacy

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells