Xylitol / Ki-67 Cancer Research Results

Xyl, Xylitol: Click to Expand ⟱
Features:
Xylitol is a naturally occurring sugar alcohol commonly found in many fruits and vegetables and is often used as a low-calorie sweetener. While xylitol is best known for its dental health benefits and as a sugar substitute, there is emerging interest in its potential roles in cancer-related research.

-Xylitol may exert antioxidant effects that help reduce oxidative stress.
-Xylitol is well known for its effects on oral bacteria. Since the microbiome can play a role in modulating systemic inflammation and even cancer risk, xylitol’s ability to alter microbial composition might have indirect implications for cancer risk or progression.
Ki-67, Ki-67 protein: Click to Expand ⟱
Source:
Type: proliferation marker
A high Ki-67 proliferation index means many cells are dividing quickly and that the cancer is likely to grow and spread.
Markers of proliferation index (Ki-67)

• Ki-67 serves primarily as a proliferation marker: higher levels are generally indicative of aggressive disease and poorer outcomes across many cancer types.
• While Ki-67 itself is not considered a driver of tumorigenesis, its expression mirrors the high proliferative activity associated with protumoral behavior.
• It is widely used in clinical practice to aid in tumor grading, prognostication, and treatment planning.
Scientific Papers found: Click to Expand⟱
1913- Xyl,    Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer
- in-vivo, Oral, NA
TumVol↓, OS↑, PFK↓, toxicity↓, Dose∅, Ki-67↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

PFK↓, 1,  

Migration ⓘ

Ki-67↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose∅, 1,  

Clinical Biomarkers ⓘ

Ki-67↓, 1,  

Functional Outcomes ⓘ

OS↑, 1,   toxicity↓, 1,   TumVol↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Ki-67, Ki-67 protein
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:298  Target#:425  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page