Wogonin / TumCP Cancer Research Results

Wog, Wogonin: Click to Expand ⟱
Features:
Wogonin is a naturally occurring flavonoid typically isolated from Scutellaria baicalensis and has been the focus of cancer research due to its potential anticancer properties.

Pathways:
-PI3K/Akt Pathway Inhibition
-NF-κB Pathway Suppression
-MAPK Pathway Modulation (ERK, JNK, and p38)
-STAT3 Signaling Inhibition:
-Reactive Oxygen Species (ROS) Generation
-Decreases in HKII, PDK1, and LDHA expression
-Suppression of lactate generation, and reduced glucose uptake
TumCP, Tumor Cell proliferation: Click to Expand ⟱
Source:
Type:
Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors.
Scientific Papers found: Click to Expand⟱
2621- Wog,    Natural compounds targeting glycolysis as promising therapeutics for gastric cancer: A review
- Review, Var, NA
Hif1a↓, MCT4↓, LDH↓, lactateProd↓, ECAR↓, TumCP↓, Glycolysis↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

ECAR↓, 1,   Glycolysis↓, 1,   lactateProd↓, 1,   LDH↓, 1,   MCT4↓, 1,  

Migration ⓘ

TumCP↓, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 1,  

Clinical Biomarkers ⓘ

LDH↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TumCP, Tumor Cell proliferation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:314  Target#:327  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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